An Observational Study to Assess Ubrogepant Tablets and Atogepant Tablets to Treat Migraine in Adult Participants

NCT ID: NCT05827887

Last Updated: 2025-12-26

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

200 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-06-25

Study Completion Date

2026-02-28

Brief Summary

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Migraine is a neurological disease characterized by moderate or severe headache, associated with nausea, vomiting, and/or sensitivity to light and sound. This study will evaluate how effective the use of ubrogepant and atogepant is in treating adult participants with migraine.

Urogepant (Ubrelvy) and Atogepant (Qulipta) are approved drugs for treatment of migraine in adults in the US. Approximately 200 adult participants who are prescribed Ubrogepant or atogepant by their doctors will be enrolled in this study in Israel.

Participants will receive ubrogepant oral tablets or atogepant oral tablets as prescribed by their physician. Participants will be followed for 90 days.

There is expected to be no additional burden for participants in this trial. Participants will attend regular visits during the study at a hospital or clinic according to their routine clinical practice.

Detailed Description

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Conditions

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Migraine

Keywords

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Migraine Ubrogepant Ubrelvy Atogepant Qulipta

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Ubrogepant

Participants will receive ubrogepant as prescribed by their physician in routine clinical practice.

No interventions assigned to this group

Atogepant

Participants will receive atogepant as prescribed by their physician in routine clinical practice.

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Confirmed diagnosis of migraine according to the ICHD-3 upon judgement of the treating physician
* The patients should be naive to the designated treatment
* Ability to fill an e-diary app

Exclusion Criteria

* Patients who cannot be treated with UBRO or ATO according to the applicable approved label
* Patients participating in a concurrent clinical interventional study or within the last 30 days
* Patients who were previously treated with rimegepant will be excluded from the study
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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AbbVie

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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ABBVIE INC.

Role: STUDY_DIRECTOR

AbbVie

Locations

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Edith Wolfson Medical Center /ID# 269740

Holon, Central District, Israel

Site Status COMPLETED

Maccabi Healthcare Services /ID# 254171

Kfar Saba, Central District, Israel

Site Status RECRUITING

Meir Medical Center /ID# 254170

Kfar Saba, Central District, Israel

Site Status RECRUITING

Shaare Zedek Medical Center /ID# 254169

Jerusalem, Jerusalem, Israel

Site Status RECRUITING

Hadassah Medical Center-Hebrew University /ID# 257352

Jerusalem, Jerusalem, Israel

Site Status RECRUITING

ZIV Medical Center /ID# 257360

Safed, Northern District, Israel

Site Status RECRUITING

Assuta Ashdod Medical Center /ID# 260020

Ashdod, Southern District, Israel

Site Status RECRUITING

Soroka University Medical Center /ID# 254551

Beersheba, Southern District, Israel

Site Status COMPLETED

The Chaim Sheba Medical Center /ID# 254550

Ramat Gan, Tel Aviv, Israel

Site Status RECRUITING

Tel Aviv Sourasky Medical Center /ID# 263089

Tel Aviv, Tel Aviv, Israel

Site Status RECRUITING

Clalit HMO /ID# 257364

Gani Tikva, , Israel

Site Status RECRUITING

Countries

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Israel

Central Contacts

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Tal Nevo

Role: CONTACT

Phone: +972(0)97909600

Email: [email protected]

Related Links

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Other Identifiers

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P24-078

Identifier Type: -

Identifier Source: org_study_id