The Ohio State University (OSU) SCREEN Community Program

NCT ID: NCT06666192

Last Updated: 2025-12-24

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

2067 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-03-12

Study Completion Date

2029-12-31

Brief Summary

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This clinical trial develops and tests how well a multi-level intervention (MLI), The Ohio State University (OSU) SCREEN Community Program, works to increase screening and follow-up for breast, cervical and colorectal (CRC) cancer among low-income and un/underinsured female residents in three counties in Central Ohio. In Ohio, incidence and mortality rates for breast, cervical and CRC are higher than or similar to the national average; in addition, underserved populations - minority, rural and low-income women - have higher rates of these cancers. Screening can detect precancerous colorectal and cervical lesions and other early-stage cancers when treatment is less intensive and more successful and is known to reduce mortality rates for breast, cervical, and CRC, however many of these women lack access to health care and screenings. This MLI includes clinic-based components, such as patient education, as well as community-based strategies, such as media programs and training health workers, that can increase rates of guideline-recommended breast, cervical and CRC screening and follow-ups in underserved populations. The OSU SCREEN Community Program may be an effective way to improve breast, cervical and CRC screenings among underserved women in Ohio.

Detailed Description

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PRIMARY OBJECTIVES:

I. Understand local factors and context relevant to breast, cervical and CRC screening and follow-up (including referral-to-care) and develop an MLI planning and implementation pathway for use by partner health centers and communities (Year 1).

II. Pilot test and further refine the MLI planning and implementation process in one clinic (Years 1 \& 2).

III. Test the final MLI planning and implementation process in a group randomized, delayed intervention trial to assess the impact of the customized MLI on increasing rates of guideline recommended breast, cervical and CRC screening and follow-up for abnormal tests (Years 2, 3 and 4).

IV. Assess sustainability of the MLI (Years 4 and 5).

OUTLINE:

PHASE I (PLANNING): Providers and community members review MLI materials and participate in focus groups and interviews to discuss challenges to being screened, what community members know about cancer and screening and what should be included in a program to increase screening over 30-60 minutes on study. A clinic champion will be identified during the interview to lead, advise, and oversee the implementation of the MLI at their clinic location.

PHASE II (PILOT): Participants are assigned to 1 of 4 arms.

ARM I (HEALTH CLINICS): The clinic champion coordinates planning sessions, staff training, and overall implementation and planning for the MLI within each health clinic. Health clinics may integrate new activities into usual clinic processes such as the use of the electronic health record (EHR) to identify age-eligible patients in need of breast, cervical and/or CRC screening, reminder systems built into the EHR that can be sent to both providers and patients for screening and follow-up, and EHR information alerts for providers about patients who have positive fecal immunochemical test (FITs) or a positive Pap test or mammogram on study. Additionally, health clinics may incorporate risk assessments (via paper or within the EHR) for all patients eligible for breast, cervical and/or CRC screening, promote screening via web-based or health portal messaging, promote annual wellness visits (during which screening should be discussed), and offer incentives for completing needed cancer screening on study.

ARM II (HEALTH CARE PROVIDERS): Providers participate in educational sessions that include self-administered pre-test surveys and discussions that assess screening knowledge, beliefs, attitudes, and practices, over one hour on study. Providers may also undergo coaching calls and one-on-one discussions to help tailor information and its delivery to the needs of providers and practices and are taught how to use clinic-based scheduling and reminder systems to help facilitate screening and follow-up actions.

ARM III (PATIENTS): Patients receive educational materials about screening and screening recommendations via mail and during in-person visits, and a web link for the developed small media website on study. Patients participate in discussions about screening and are offered any test for which they are not up to date and appropriate follow-up is conducted by designated staff on study. Patients who choose to undergo testing and receive a positive result receive a letter from the clinic and a call from the designated clinic staff member on study.

ARM IV (COMMUNITY): Communities receive educational materials (e.g., posters) and outreach activities to promote screening (e.g., health fairs, farmers' markets, inflatable colon tours, community seminars) and receive access to a community health worker (CHW) for one-on-one education about screening on study.

PHASE III and IV: Participating clinics and surrounding communities are randomized to 1 of 2 arms.

ARM V (EARLY INTERVENTION WAVE): Participating clinics and communities participate in the MLI early (years 2-3) for up to 30 months.

ARM VI (DELAYED INTERVENTION WAVE): Participating clinics and communities participate in the MLI 12 months later (years 3-4) for at least 12 months.

Conditions

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Breast Carcinoma Cervical Carcinoma Colorectal Carcinoma

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

SEQUENTIAL

Primary Study Purpose

SCREENING

Blinding Strategy

NONE

Study Groups

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Phase I, Planning Phase (MLI material, focus group, interview)

Providers and community members review MLI materials and participate in focus groups and interviews to discuss challenges to being screened, what community members know about cancer and screening and what should be included in a program to increase screening over 30-60 minutes on study. A clinic champion will be identified during the interview to lead, advise, and oversee the implementation of the MLI at their clinic location.

Group Type OTHER

Focus Group

Intervention Type BEHAVIORAL

Participate in focus group

Informational Intervention

Intervention Type OTHER

Review MLI materials

Interview

Intervention Type OTHER

Participate in interview

Phase II, Arm I (Health Clinics)

The clinic champion coordinates planning sessions, staff training, and overall implementation and planning for the MLI within each health clinic. Health clinics may integrate new activities into usual clinic processes such as the use of the EHR to identify age-eligible patients in need of breast, cervical and/or CRC screening, reminder systems built into the EHR that can be sent to both providers and patients for screening and follow-up, and EHR information alerts for providers about patients who have positive FITs or a positive Pap test or mammogram on study. Additionally, health clinics may incorporate risk assessments (via paper or within the EHR) for all patients eligible for breast, cervical and/or CRC screening, promote screening via web-based or health portal messaging, promote annual wellness visits (during which screening should be discussed), and offer incentives for completing needed cancer screening on study.

Group Type ACTIVE_COMPARATOR

Health Care Delivery

Intervention Type OTHER

Integrate new activities into usual clinic processes

Health Promotion

Intervention Type OTHER

Promote screening and wellness visits

Health Risk Assessment

Intervention Type BEHAVIORAL

Incorporate risk assessments

Implementation

Intervention Type PROCEDURE

Implement MLI

Patient Navigation

Intervention Type BEHAVIORAL

Receive access to CHW

Phase II, Arm II (Health Care Providers)

Providers participate in educational sessions that include self-administered pre-test surveys and discussions that assess screening knowledge, beliefs, attitudes, and practices, over one hour on study. Providers may also undergo coaching calls and one-on-one discussions to help tailor information and its delivery to the needs of providers and practices and are taught how to use clinic-based scheduling and reminder systems to help facilitate screening and follow-up actions.

Group Type ACTIVE_COMPARATOR

Discussion

Intervention Type OTHER

Participate in discussions

Educational Activity

Intervention Type OTHER

Receive coaching calls

Health Care Delivery

Intervention Type OTHER

Integrate new activities into usual clinic processes

Health Promotion and Education

Intervention Type OTHER

Participate in educational sessions

Survey Administration

Intervention Type OTHER

Ancillary studies

Phase II, Arm III (Patients)

Patients receive educational materials about screening and screening recommendations via mail and during in-person visits, and a web link for the developed small media website on study. Patients participate in discussions about screening and are offered any test for which they are not up to date and appropriate follow-up is conducted by designated staff on study. Patients who choose to undergo testing and receive a positive result receive a letter from the clinic and a call from the designated clinic staff member on study.

Group Type ACTIVE_COMPARATOR

Cancer Screening

Intervention Type OTHER

Undergo cancer screening

Discussion

Intervention Type OTHER

Participate in discussions

Educational Intervention

Intervention Type OTHER

Receive educational materials

Internet-Based Intervention

Intervention Type OTHER

Receive educational online materials

Phase II, Arm IV (Community)

Community receive educational materials (e.g., posters) and outreach activities to promote screening (e.g., health fairs, farmers' markets, inflatable colon tours, community seminars) and receive access to a CHW for one-on-one education about screening on study.

Group Type ACTIVE_COMPARATOR

Discussion

Intervention Type OTHER

Participate in discussions

Educational Intervention

Intervention Type OTHER

Receive educational materials

Outreach

Intervention Type BEHAVIORAL

Receive outreach activities

Patient Navigation

Intervention Type BEHAVIORAL

Receive access to CHW

Phase III and IV, Arm V (MLI Early Wave)

Participating clinics and communities participate in the MLI early (years 2-3) for up to 30 months.

Group Type EXPERIMENTAL

Health Promotion and Education

Intervention Type OTHER

Participate in early wave MLI

Phase III and IV, Arm VI (MLI Delayed Wave)

Participating clinics and communities participate in the MLI 12 months later (years 3-4) for at least 12 months.

Group Type EXPERIMENTAL

Health Promotion and Education

Intervention Type OTHER

Participate in late wave MLI

Interventions

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Cancer Screening

Undergo cancer screening

Intervention Type OTHER

Discussion

Participate in discussions

Intervention Type OTHER

Educational Activity

Receive coaching calls

Intervention Type OTHER

Educational Intervention

Receive educational materials

Intervention Type OTHER

Focus Group

Participate in focus group

Intervention Type BEHAVIORAL

Health Care Delivery

Integrate new activities into usual clinic processes

Intervention Type OTHER

Health Promotion

Promote screening and wellness visits

Intervention Type OTHER

Health Promotion and Education

Participate in educational sessions

Intervention Type OTHER

Health Promotion and Education

Participate in early wave MLI

Intervention Type OTHER

Health Promotion and Education

Participate in late wave MLI

Intervention Type OTHER

Health Risk Assessment

Incorporate risk assessments

Intervention Type BEHAVIORAL

Implementation

Implement MLI

Intervention Type PROCEDURE

Informational Intervention

Review MLI materials

Intervention Type OTHER

Internet-Based Intervention

Receive educational online materials

Intervention Type OTHER

Interview

Participate in interview

Intervention Type OTHER

Outreach

Receive outreach activities

Intervention Type BEHAVIORAL

Patient Navigation

Receive access to CHW

Intervention Type BEHAVIORAL

Survey Administration

Ancillary studies

Intervention Type OTHER

Other Intervention Names

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Cancer Screening for Patients Early Cancer Detection Screening Screening of Cancer Discuss Education for Intervention Intervention by Education Intervention through Education Intervention, Educational Care Delivery Health Services Delivery, Other Healthcare Delivery Health Promotion (Salutogenesis) Health Promotion and Wellness Mindfulness Health Promotion Salutogenesis Risk Assessment Outreach Strategy Patient Navigator Program

Eligibility Criteria

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Inclusion Criteria

* Level 1 is the health clinics (Helping Hands \[pilot\]; 6 Lower Lights clinics). Clinics are eligible if they provide preventive health care to residents of the targeted census tracts.
* Level 2 focuses on health care providers (physicians, nurses, physician assistants \[PA\]/nurse practitioners \[NPs\]) and office staff practicing at participating clinics who are involved in the screening and/or screening referral process (determined by individual clinical sites) and can speak, read, and write English
* Patients (Level 3) are the recipients of health care and screening interventional strategies implemented by clinics and providers.
* Level 4 is the community to include residents in targeted census tracts around each clinic.
Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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American Cancer Society, Inc.

OTHER

Sponsor Role collaborator

Ohio State University Comprehensive Cancer Center

OTHER

Sponsor Role lead

Responsible Party

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Electra Paskett

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Electra D Paskett, PhD

Role: PRINCIPAL_INVESTIGATOR

Ohio State University Comprehensive Cancer Center

Locations

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Ohio State University Comprehensive Cancer Center

Columbus, Ohio, United States

Site Status RECRUITING

Countries

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United States

Central Contacts

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The Ohio State University Comprehensive Cancer Center

Role: CONTACT

Phone: 800-293-5066

Email: [email protected]

Facility Contacts

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Electra D. Paskett, PhD

Role: primary

Related Links

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Other Identifiers

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NCI-2024-07400

Identifier Type: REGISTRY

Identifier Source: secondary_id

OSU-23400

Identifier Type: -

Identifier Source: org_study_id