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Clinical Trials

Showing trials with last updates posted in 2025.

NCT06957028 | RECRUITING | NA
6000 Participants

CGM for the Early Detection and Management of Hyperglycemia in Pregnancy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2025-05-27
Completion: 2027-11-27
Conditions
Gestational Diabetes Mellitus in Pregnancy
Interventions
OTHER
No Results Yet
NCT06951711 | RECRUITING | PHASE3
274 Participants

A Study to Evaluate the Efficacy and Safety of KarXT for the Treatment of Manic Episodes in Bipolar-I Disorder (BALSAM-2)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2025-06-13
Completion: 2026-11-02
Conditions
Bipolar Disorder Type I With Mania or Mania With Mixed Features
Interventions
DRUG OTHER
No Results Yet
NCT06943872 | RECRUITING | PHASE3
630 Participants

A Study to Investigate Progression-Free Survival With Sonrotoclax Plus Obinutuzumab Or Sonrotoclax Plus Rituximab Compared With Venetoclax Plus Rituximab Treatment In Patients With Relapsed and/or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CELESTIAL-RRCLL)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2025-06-11
Completion: 2029-09-30
Conditions
Chronic Lymphocytic Leukemia Small Lymphocytic Lymphoma
Interventions
DRUG
No Results Yet
NCT06943859 | RECRUITING | PHASE2
50 Participants

Ketamine for Opioid Use Disorder

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2026-01-31
Completion: 2028-08-31
Conditions
Opioid Use Disorder
Interventions
DRUG
No Results Yet
NCT06942702 | NOT_YET_RECRUITING | NA
44 Participants

Efficacy of Genicular Block on Total Knee Arthroplasty Surgery

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2025-12-20
Completion: 2026-10-20
Conditions
Total Knee Anthroplasty Genicular Nerves Block
Interventions
DRUG
No Results Yet
NCT06936943 | RECRUITING | PHASE2
14 Participants

ONO-4538 Study in Patients With Richter's Transformation

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2025-11-19
Completion: 2029-07-31
Conditions
Richter's Transformation
Interventions
DRUG
No Results Yet
NCT06934967 | RECRUITING | PHASE3
12 Participants

Study to Assess the Pharmacokinetics, Safety, and Tolerability of Iptacopan in Pediatric PNH Patients

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2025-10-28
Completion: 2031-11-19
Conditions
Paroxysmal Nocturnal Hemoglobinuria (PNH)
Interventions
DRUG
No Results Yet
NCT06932809 | RECRUITING | EARLY_PHASE1
90 Participants

Study of Biodistribution, Metabolism, Excretion and Brain Uptake 18F-JSS20-183A

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2025-05-09
Completion: 2030-04-30
Conditions
Tauopathies
Interventions
DRUG DIAGNOSTIC_TEST BEHAVIORAL
No Results Yet
NCT06932302 | RECRUITING | NA
24 Participants

At-Home Neuromodulation for Female Sexual Dysfunction

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2025-10-15
Completion: 2027-10-31
Conditions
Female Sexual Dysfunction
Interventions
DEVICE
No Results Yet
NCT06929273 | RECRUITING | PHASE3
450 Participants

A Study to Assess the Long-term Safety of KarXT for the Treatment of Manic Episodes in Bipolar-I Disorder (BALSAM-3)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2025-07-18
Completion: 2028-06-13
Conditions
Bipolar Disorder Type I With Mania
Interventions
DRUG
No Results Yet
NCT06927973 | COMPLETED | NA
30 Participants

Leveraging Exercise Stress Echocardiography for Heart Failure With Preserved Ejection Fraction

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2025-05-30
Completion: 2025-12-19
Conditions
Chest Pain Shortness of Breath
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT06925022 | ACTIVE_NOT_RECRUITING | NA
30 Participants

Educational Programs Based on Healthy Habits to Improve Quality of Life and Psychosocial Profile in Women With Neurodegenerative Diseases: The ADVICE Protocol Study (Phase 1)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2024-12-15
Completion: 2025-06-30
Conditions
Multiple Sclerosis (MS) - Relapsing-remitting
Interventions
OTHER
No Results Yet
NCT06912724 | RECRUITING
80 Participants

Pediatric Neuroimaging

Study Type: OBSERVATIONAL
Last Updated: 2025-12-23
Start Date: 2025-04-21
Completion: 2026-05-01
Conditions
Neurogimaging
No Results Yet
NCT06910358 | RECRUITING | PHASE3
150 Participants

Study of Bitopertin in Participants With EPP or XLP (APOLLO)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2025-04-04
Completion: 2026-10-31
Conditions
Erythropoietic Protoporphyria (EPP) X-Linked Protoporphyria (XLP)
Interventions
DRUG
No Results Yet
NCT06909422 | NOT_YET_RECRUITING | NA
100 Participants

Mobile Thinking Intervention: A Inital Test

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2026-05-31
Completion: 2028-08-31
Conditions
Schizophrenia Clinical High Risk for Psychosis (CHR)
Interventions
BEHAVIORAL
No Results Yet
NCT06908317 | COMPLETED | NA
26 Participants

Teaching the Getting Up From the Floor Among Long-Term Care Facility Residents

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2025-04-14
Completion: 2025-10-17
Conditions
Mobility Difficulty Exercise ELDERLY PEOPLE
Interventions
OTHER
No Results Yet
NCT06906328 | RECRUITING | NA
248 Participants

MEthylphenidate in ADHD - Addiction(s) Comorbidity: Value of Adding a Cognitive Remediation Program to Improve Short- and Medium-term Therapeutic Response

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2025-12-11
Completion: 2028-12-11
Conditions
ADHD-add
Interventions
BEHAVIORAL
No Results Yet
NCT06904274 | RECRUITING | PHASE3
207 Participants

Mirena for the Treatment of Nonatypical Endometrial Hyperplasia for 6 Months

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2025-11-24
Completion: 2027-05-03
Conditions
Endometrial Hyperplasia
Interventions
COMBINATION_PRODUCT DRUG
No Results Yet
NCT06902519 | RECRUITING | PHASE1
75 Participants

Study of GS-0151 in Participants With Rheumatoid Arthritis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2025-05-14
Completion: 2027-03-31
Conditions
Rheumatoid Arthritis
Interventions
DRUG
No Results Yet
NCT06901362 | COMPLETED
401 Participants

Seroprevalence and Vaccination Rate of Hepatitis B Virus and Varicella-zoster Virus Among Medical Students Under Immunizing Program

Study Type: OBSERVATIONAL
Last Updated: 2025-12-23
Start Date: 2025-04-01
Completion: 2025-08-31
Conditions
Healthy Healthy Adult
No Results Yet
NCT06899022 | RECRUITING | NA
138 Participants

Attention and Eye Movement in Parkinson's Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2025-09-22
Completion: 2028-02-29
Conditions
Essential Tremor Parkinson's Disease (PD)
Interventions
OTHER
No Results Yet
NCT06891755 | RECRUITING | NA
250 Participants

Bronchoscopic RElease of Air Trapped in Hyperinflated Emphysematous Lung - Study 3

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2025-07-15
Completion: 2027-09-30
Conditions
COPD Emphysema
Interventions
DEVICE OTHER
No Results Yet
NCT06888817 | RECRUITING | PHASE3
408 Participants

Bevacizumab Versus Corticosteroids as First-line Treatment in Patients With Symptomatic Cerebral Radiation Necrosis After Radiation for High-grade Glioma or Brain Metastases

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2025-06-19
Completion: 2028-07-31
Conditions
Radiation Necrosis High Grade Glioma (III or IV) Brain Metastasases Radiation Toxicity Radiation Effect Radiation Injury Radiation Injuries
Interventions
DRUG
No Results Yet
NCT06887192 | RECRUITING | PHASE2
300 Participants

A Study to Assess the Efficacy and Safety of ML-007C-MA for the Treatment of Alzheimer's Disease Psychosis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2025-08-15
Completion: 2027-02-28
Conditions
Psychosis Associated With Alzheimer's Disease
Interventions
DRUG
No Results Yet
NCT06883240 | RECRUITING
40 Participants

An Observational Study of Participants With Type 3 Von Willebrand Disease on Prophylactic Standard-of-Care Treatment

Study Type: OBSERVATIONAL
Last Updated: 2025-12-23
Start Date: 2025-04-29
Completion: 2026-11-01
Conditions
Von Willebrand Disease, Type 3
Interventions
DRUG
No Results Yet
NCT06873581 | RECRUITING | PHASE3
266 Participants

Pivotal Study of Voro Urologic Scaffold

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2025-04-18
Completion: 2027-02-01
Conditions
Radical Prostatectomy Stress Urinary Incontinence (SUI)
Interventions
DEVICE
No Results Yet
NCT06870383 | RECRUITING | NA
66 Participants

Erector Spinae Block Versus Combined Pecto-intercostal and Recto-intercostal Fascial Plane Block in Cardiac Surgery

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2025-03-20
Completion: 2026-03-20
Conditions
Erector Spinae Plane Block Pecto-intercostal Fascial Plane Block Recto-intercostal Fascial Plane Block Cardiac Surgery
Interventions
DRUG
No Results Yet
NCT06863402 | RECRUITING | PHASE2
32 Participants

Nemtabrutinib and Pembrolizumab for the Treatment of Richter Transformation, Diffuse Large B-cell Lymphoma Subtype

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2026-02-15
Completion: 2029-04-01
Conditions
Richter Syndrome Diffuse Large B-Cell Lymphoma Chronic Lymphocytic Leukemia
Interventions
PROCEDURE DRUG BIOLOGICAL OTHER
No Results Yet
NCT06863337 | RECRUITING | NA
100 Participants

Glucose Pattern in Infertile Women Receiving Assisted Reproduction Using Continuous Glucose Monitoring

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2025-03-26
Completion: 2026-06-30
Conditions
Infertility Female
Interventions
DEVICE
No Results Yet
NCT06850805 | RECRUITING | PHASE3
84 Participants

Efficacy and Safety of 186 mcg of OPN-375 Nasal Spray Twice a Day (BID) in Adolescents With Chronic Rhinosinusitis Without Nasal Polyps

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2025-07-28
Completion: 2028-03-31
Conditions
Chronic Rhinosinusitis Without Nasal Polyps
Interventions
DRUG
No Results Yet
NCT06849596 | RECRUITING | NA
780 Participants

Manual T-piece Versus Ventilator Positive Pressure Ventilation During Resuscitation of Extremely Premature Neonates

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2025-12-01
Completion: 2028-09-30
Conditions
Neonatal Resuscitation Apnea Neonatal
Interventions
DEVICE
No Results Yet
NCT06846099 | COMPLETED | PHASE1
69 Participants

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Efficacy and Indications of RP903

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2022-12-07
Completion: 2025-05-30
Conditions
Ovarian Cancer Cervical Cancer Endometrial Cancer Breast Cancer Solid Tumor Cancer
Interventions
DRUG
No Results Yet
NCT06840210 | NOT_YET_RECRUITING
200000 Participants

Effectiveness-Implementation Evaluation of Acute Kidney Injury Decision Support

Study Type: OBSERVATIONAL
Last Updated: 2025-12-23
Start Date: 2026-02-01
Completion: 2028-12-01
Conditions
Acute Kidney Injury
No Results Yet
NCT06838676 | RECRUITING | PHASE2
60 Participants

ACT001 for the Treatment of Diffuse Intrinsic Pontine Gliomas and H3K27-altered High Grade Gliomas

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2025-07-10
Completion: 2028-07-31
Conditions
Diffuse Intrinsic Pontine Gliomas (DIPG) Progressive DIPG Refractory DIPG Recurrent DIPG H3K27-altered High Grade Glioma
Interventions
DRUG
No Results Yet
NCT06835491 | RECRUITING | PHASE3
674 Participants

Prophylactic Anti-aRrhythmic Therapy With Amiodarone in Critically Ill Patients Admitted for an Out-of-hospital Cardiac Arrest With Initial Shockable Rhythm

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2025-11-06
Completion: 2027-01-15
Conditions
Ventricular Arrhythmias and Cardiac Arrest
Interventions
DRUG
No Results Yet
NCT06834191 | RECRUITING
80 Participants

Relationship Between Immunosuppressive Treatment Status and Clinical Course of Parkinson's Disease

Study Type: OBSERVATIONAL
Last Updated: 2025-12-23
Start Date: 2025-03-01
Completion: 2027-12-31
Conditions
Parkinson Disease
No Results Yet
NCT06828328 | RECRUITING | EARLY_PHASE1
10 Participants

A Study of GC203 TIL in PDCA (RJ)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2025-02-10
Completion: 2028-01-31
Conditions
Pancreatic Cancer Pancratic Ductal Adenocarcinoma Treatment Side Effects Tumor Infiltrating Lymphocytes
Interventions
BIOLOGICAL
No Results Yet
NCT06824064 | RECRUITING | PHASE2
150 Participants

Evaluation of RBS2418 in Patients With Advanced, Metastatic, and Progressive Colorectal Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2025-01-17
Completion: 2027-12-31
Conditions
Metastatic Colorectal Cancer Advanced Colorectal Cancer
Interventions
DRUG
No Results Yet
NCT06822491 | ACTIVE_NOT_RECRUITING
28 Participants

Early Magnetic Resonance Imaging Response of the Dominant Intraprostatic Lesion After Online Adaptive Stereotactic Body Radiotherapy for Localized Prostate Cancer and Correlation With Prostate Specific Antigen Response

Study Type: OBSERVATIONAL
Last Updated: 2025-12-23
Start Date: 2024-08-20
Completion: 2026-06-30
Conditions
Prostate Carcinoma Localized Prostate Adenocarcinoma Stereotactic Body Radiotherapy Stereotactic Radiotherapy Magnetic Resonance Imaging Multiparametric MRI
No Results Yet
NCT06818136 | RECRUITING
600 Participants

Bladder EpiCheck European Haematuria Study

Study Type: OBSERVATIONAL
Last Updated: 2025-12-23
Start Date: 2025-06-20
Completion: 2026-02-28
Conditions
Hematuria Cystoscopy Urothelial Carcinoma Bladder Urothelial Carcinoma of the Renal Pelvis and Ureter Urothelial Carcinoma of the Urinary Bladder
Interventions
DIAGNOSTIC_TEST
No Results Yet
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