Clinical Trials

Showing trials with last updates posted in 2025.

NCT04587739 | RECRUITING | PHASE1
30 Participants

Neoadjuvant Hypofractionated Stereotactic Body Radiation Therapy Prior to Surgery for Hepatocellular Carcinoma: a Feasibility Study.

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2021-01-31
Completion: 2028-01-31
Conditions
Hepatocellular Carcinoma
Interventions
COMBINATION_PRODUCT
No Results Yet
NCT04583800 | RECRUITING
600 Participants

Prediction of Heart Failure and Cognitive Decline in Type 2 Diabetes

Study Type: OBSERVATIONAL
Last Updated: 2025-12-23
Start Date: 2021-06-22
Completion: 2026-06-30
Conditions
Diabetes Mellitus, Type 2 Heart Failure Cognitive Decline
No Results Yet
NCT04583475 | COMPLETED
163 Participants

Real-life Study of How to Intensify Treatment With Xolair (OMALIZUMAB) in Chronic Spontaneous Urticaria

Study Type: OBSERVATIONAL
Last Updated: 2025-12-23
Start Date: 2021-02-25
Completion: 2023-06-22
Conditions
Spontaneous Urticaria, Chronic
No Results Yet
NCT04578834 | COMPLETED | PHASE3
518 Participants

Study of Efficacy and Safety of LNP023 in Primary IgA Nephropathy Patients

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2021-01-25
Completion: 2025-09-19
Conditions
IgA Nephropathy
Interventions
DRUG
No Results Yet
NCT04573673 | RECRUITING | NA
68 Participants

Transcutaneous Tibial Neuro-stimulation to Improve Voiding Dysfunction in Multiple Sclerosis.

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2021-12-01
Completion: 2026-06-30
Conditions
Multiple Sclerosis Lower Urinary Tract Symptoms
Interventions
DEVICE
No Results Yet
NCT04560712 | ACTIVE_NOT_RECRUITING | NA
70 Participants

Acupuncture for the Management of Postoperative Pain in Patients With Pancreatic or Colorectal Cancer Undergoing Surgery

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2020-08-12
Completion: 2027-12-31
Conditions
Resectable Colorectal Carcinoma Resectable Digestive System Carcinoma Resectable Pancreatic Carcinoma
Interventions
PROCEDURE OTHER
No Results Yet
NCT04546594 | WITHDRAWN
0 Participants

Epidemiological Data on Pain

Study Type: OBSERVATIONAL
Last Updated: 2025-12-23
Start Date: 2020-10-31
Completion: 2025-12-31
Conditions
Orthopedic Disorder Thoracic Gynecological; Surgery (Previous), Causing Obstructed Labor, Affecting Fetus Pain
No Results Yet
NCT04540835 | COMPLETED | NA
50 Participants

Evaluation of the Effectiveness of Calcium Phosphate Containing Desensitizer on Postoperative Sensitivity

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2021-10-01
Completion: 2022-10-01
Conditions
Postoperative Pain
Interventions
DEVICE
NCT04540822 | COMPLETED | NA
360 Participants

Peripheral Catheter Pressure Ulcer Prevention in Pediatry : Use of Compresses Versus Standard Care

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2020-09-22
Completion: 2024-06-03
Conditions
Pressure Ulcer
Interventions
OTHER
NCT04538664 | ACTIVE_NOT_RECRUITING | PHASE3
308 Participants
NCT04530760 | RECRUITING
226 Participants

Intraabdominal Hypertension and Occurrence of Microaspiration in Cirrhotics Under Mechanical Ventilation

Study Type: OBSERVATIONAL
Last Updated: 2025-12-23
Start Date: 2021-10-08
Completion: 2026-12-31
Conditions
Critical Illness Cirrhosis, Liver
No Results Yet
NCT04530734 | RECRUITING
100 Participants

Blood Concentration in Lorazepam and Treatment in Adult Catatonia

Study Type: OBSERVATIONAL
Last Updated: 2025-12-23
Start Date: 2020-01-01
Completion: 2026-01-31
Conditions
Catatonia
No Results Yet
NCT04522193 | RECRUITING | NA
15 Participants

Dumping Syndrome and Esophageal Atresia

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2024-02-23
Completion: 2026-11-30
Conditions
Oesophageal Atresia Dumping Syndrome
Interventions
DEVICE RADIATION
No Results Yet
NCT04514133 | RECRUITING | NA
2500 Participants

Testing the Causal Effects of a Civic Engagement Intervention on Health and Wellbeing Among Youth (I-ACTED)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2021-06-24
Completion: 2026-01-31
Conditions
Mental Health Wellness 1 Social Interaction Health Attitude
Interventions
BEHAVIORAL
No Results Yet
NCT04510792 | WITHDRAWN
0 Participants

IMpact of hyPeRkalaemia on thErapy With Renin angiotenSin aldoSterone System Inhibitors

Study Type: OBSERVATIONAL
Last Updated: 2025-12-23
Start Date: 2021-07-12
Completion: 2021-07-12
Conditions
Hyperkalemia
Interventions
OTHER
No Results Yet
NCT04503278 | RECRUITING | PHASE1
214 Participants

A Clinical Study of the Safety and Effectiveness of an Investigational Cell Therapy Given With and Without an Investigational RNA-based Vaccine in Patients With Organ Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2020-09-16
Completion: 2028-12-31
Conditions
Solid Tumor
Interventions
BIOLOGICAL
No Results Yet
NCT04487080 | ACTIVE_NOT_RECRUITING | PHASE3
1074 Participants

A Study of Amivantamab and Lazertinib Combination Therapy Versus Osimertinib in Locally Advanced or Metastatic Non-Small Cell Lung Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2020-09-30
Completion: 2023-08-11
Conditions
Carcinoma, Non-Small-Cell Lung
Interventions
DRUG
NCT04475211 | COMPLETED
757 Participants

LILLE COVID RESEARCH NETWORK (Covid-19)

Study Type: OBSERVATIONAL
Last Updated: 2025-12-23
Start Date: 2020-08-10
Completion: 2022-06-15
Conditions
Sars-CoV2
No Results Yet
NCT04463589 | COMPLETED
174 Participants

Presenteeism in Severe Asthma Treated by Biotherapyasthma

Study Type: OBSERVATIONAL
Last Updated: 2025-12-23
Start Date: 2021-01-01
Completion: 2024-06-10
Conditions
Asthma
No Results Yet
NCT04455841 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2
84 Participants

INCB000928 Administered as a Monotherapy or in Combination With Ruxolitinib in Participants With Anemia Due to Myeloproliferative Disorders

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2021-03-19
Completion: 2025-04-01
Conditions
Anemia Post-essential Thrombocythemia Myelofibrosis Post-polycythemia Vera Myelofibrosis
Interventions
DRUG
No Results Yet
NCT04434586 | RECRUITING | NA
166 Participants

Contribution of Optical Coherence Tomography in the Endovascular Treatment of Femoral Occlusions

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2020-06-16
Completion: 2026-06-30
Conditions
Superficial Femoral Artery Stenosis Claudication Ischemic Leg
Interventions
DEVICE
No Results Yet
NCT04407247 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2
47 Participants

Infliximab or Vedolizumab in Treating Immune Checkpoint Inhibitor-Related Colitis in Patients With Genitourinary Cancer or Melanoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2020-07-09
Completion: 2027-12-31
Conditions
Colitis Lung Non-Small Cell Carcinoma Malignant Genitourinary System Neoplasm Malignant Solid Neoplasm Melanoma
Interventions
BIOLOGICAL
No Results Yet
NCT04405362 | WITHDRAWN
0 Participants

Consequences of the QUARANTINE Relating to the COvid-19 Epidemic on the Mental Health of the Patients Followed in PSYchiatry

Study Type: OBSERVATIONAL
Last Updated: 2025-12-23
Start Date: 2020-05-31
Completion: 2021-05-31
Conditions
SARS-CoV 2 Traumatic Stress Disorder
No Results Yet
NCT04395599 | COMPLETED | NA
2 Participants

Risk of Air Contamination During Visceral Surgery in COVID19 Patients

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2021-11-16
Completion: 2022-01-27
Conditions
Sars-CoV2 Surgery COVID
Interventions
OTHER
No Results Yet
NCT04377880 | COMPLETED
20 Participants

Development of Cellular Models for Osteoblast Response Study to Adipocytic Secretions in an Osteoporosis Context.

Study Type: OBSERVATIONAL
Last Updated: 2025-12-23
Start Date: 2020-10-15
Completion: 2024-09-04
Conditions
Osteoporosis
No Results Yet
NCT04372537 | COMPLETED | NA
6 Participants

Medical Hypnosis Against Anxiety and Pain in Electro-neuro-myography

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2021-03-22
Completion: 2024-04-29
Conditions
Anxiety
Interventions
BEHAVIORAL
No Results Yet
NCT04365998 | RECRUITING | NA
15 Participants

BUBOLight®, a New Phototherapy Device for the Treatment of the Newborn's Jaundice

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2020-10-08
Completion: 2026-12-31
Conditions
Neonatal Jaundice
Interventions
DEVICE
No Results Yet
NCT04359602 | ACTIVE_NOT_RECRUITING
5090 Participants

COVID-19 Recovered Volunteer Research Participant Pool Registry

Study Type: OBSERVATIONAL
Last Updated: 2025-12-23
Start Date: 2020-04-08
Completion: 2021-09-29
Conditions
Recovered From COVID-19
No Results Yet
NCT04355689 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2
49 Participants

Safety and Efficacy of NPI-001 Tablets for RP Associated With Usher Syndrome

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2020-09-03
Completion: 2025-06-20
Conditions
Usher Syndromes
Interventions
DRUG OTHER
No Results Yet
NCT04341792 | COMPLETED
373 Participants

Predictive Biomarkers of Secondary Aggravation in Covid-19 Suspect Patient

Study Type: OBSERVATIONAL
Last Updated: 2025-12-23
Start Date: 2020-04-11
Completion: 2020-11-12
Conditions
Infection Viral Coronavirus COVID-19
No Results Yet
NCT04340492 | COMPLETED | NA
89 Participants

Education for Adapted Physical Activity in Parkinson's Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2021-03-15
Completion: 2025-10-28
Conditions
Parkinson Disease
Interventions
OTHER
No Results Yet
NCT04330118 | RECRUITING
80 Participants

Origin and Function of Eosinophilic Polynuclear During DRESS Syndrome

Study Type: OBSERVATIONAL
Last Updated: 2025-12-23
Start Date: 2020-07-15
Completion: 2026-10-31
Conditions
Drug Hypersensitivity DRESS Syndrome
No Results Yet
NCT04269213 | ACTIVE_NOT_RECRUITING | PHASE2
21 Participants

CPX-351 for the Treatment of Secondary Acute Myeloid Leukemia in Patients Younger Than 60 Years Old

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2021-07-29
Completion: 2025-04-10
Conditions
Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome Acute Myeloid Leukemia With Myelodysplasia-Related Changes Secondary Acute Myeloid Leukemia Therapy-Related Acute Myeloid Leukemia
Interventions
DRUG
No Results Yet
NCT04269200 | ACTIVE_NOT_RECRUITING | PHASE3
805 Participants

Durvalumab With or Without Olaparib as Maintenance Therapy After First-Line Treatment of Advanced and Recurrent Endometrial Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2020-05-05
Completion: 2024-07-08
Conditions
Endometrial Neoplasms
Interventions
DRUG BIOLOGICAL
NCT04246086 | RECRUITING | PHASE1/PHASE2
237 Participants

A Study Evaluating the Safety, Pharmacokinetics, and Efficacy of Mosunetuzumab + Lenalidomide (+Len), and the Safety, Tolerability, and Pharmacokinetics of SC Versus IV Mosunetuzumab + Len in Participants With Follicular Lymphoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2020-08-12
Completion: 2030-10-15
Conditions
Follicular Lymphoma
Interventions
DRUG
No Results Yet
NCT04245397 | RECRUITING | PHASE1
151 Participants

Study of SX-682 Alone and in Combination With Oral or Intravenous Decitabine in Subjects With Myelodysplastic Syndrome

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2020-06-30
Completion: 2028-03-31
Conditions
Myelodysplastic Syndromes
Interventions
DRUG
No Results Yet
NCT04199143 | COMPLETED | NA
30 Participants

Brain Reactivity to Nitrous Oxyde in Depression : an MRI and Ultrasound Study (PROTOBRAIN Pilote)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2020-02-20
Completion: 2021-06-10
Conditions
Treatment Resistant Depression Nitrous Oxyde
Interventions
DRUG DEVICE
No Results Yet
NCT04195607 | COMPLETED
298 Participants

Epidemiological Profile of Children With Early Caries.

Study Type: OBSERVATIONAL
Last Updated: 2025-12-23
Start Date: 2019-11-19
Completion: 2023-12-14
Conditions
Dental Caries
No Results Yet
NCT04195347 | RECRUITING | PHASE1/PHASE2
42 Participants

Study of CM4620 to Reduce the Severity of Pancreatitis Due to Asparaginase

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2020-09-04
Completion: 2027-01-31
Conditions
Acute Pancreatitis
Interventions
DRUG
No Results Yet
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