Clinical Trials

Showing trials with last updates posted in 2025.

NCT05815810 | NOT_YET_RECRUITING | NA
50 Participants

Novel Delivery Method of Transgender Voice Therapy Using a Mobile Application

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2026-12-31
Completion: 2027-12-31
Conditions
Transitioning Voice of Transgender and Gender Diverse People
Interventions
OTHER
No Results Yet
NCT05800964 | ACTIVE_NOT_RECRUITING | PHASE1
37 Participants

Study to Explore the Safety, Tolerability, and Pharmacokinetics of AMG 305 in Subjects With Advanced Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2023-06-13
Completion: 2026-04-10
Conditions
Advanced Solid Tumors
Interventions
DRUG
No Results Yet
NCT05799521 | RECRUITING | PHASE2
40 Participants

A Nasal Treatment for COVID-19

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2023-06-27
Completion: 2026-03-30
Conditions
COVID-19 Healthy
Interventions
DRUG
No Results Yet
NCT05797610 | RECRUITING | PHASE3
428 Participants

A Study to Evaluate the Efficacy and Safety of Sefaxersen (RO7434656) in Participants With Primary Immunoglobulin A (IgA) Nephropathy at High Risk of Progression

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2023-08-08
Completion: 2026-08-31
Conditions
Primary IgA Nephropathy
Interventions
DRUG
No Results Yet
NCT05789303 | RECRUITING | PHASE2
83 Participants

Study of Belantamab Mafodotin With Carfilzomib, Pomalidomide, and Dexamethasone in Relapsed Multiple Myeloma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2023-05-30
Completion: 2028-07-01
Conditions
Multiple Myeloma Relapse Multiple Myeloma
Interventions
DRUG
No Results Yet
NCT05785897 | RECRUITING | NA
350 Participants

STEMI Treated With a Polymer-free Sirolimus-coated Stent and P2Y12 Inhibitor-based SAPT Versus Conventional DAPT

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2025-11-01
Completion: 2027-03-01
Conditions
ST Elevation Myocardial Infarction
Interventions
DEVICE
No Results Yet
NCT05785221 | ACTIVE_NOT_RECRUITING | NA
117 Participants

Energy Metabolism Profiles Over Weight-loss and Eating Responses

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2023-03-02
Completion: 2025-03-01
Conditions
Homeostasis Metabolism and Nutrition Disorder Healthy Obesity
Interventions
BEHAVIORAL
No Results Yet
NCT05776277 | ACTIVE_NOT_RECRUITING | PHASE3
200 Participants

Iltamiocel Compared to Placebo for Chronic Fecal Incontinence in Females With Obstetric Injury

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2024-03-21
Completion: 2026-12-31
Conditions
Fecal Incontinence
Interventions
BIOLOGICAL OTHER
No Results Yet
NCT05774951 | RECRUITING | PHASE3
4300 Participants

A Study of Camizestrant in ER+/HER2- Early Breast Cancer After at Least 2 Years of Standard Adjuvant Endocrine Therapy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2023-03-31
Completion: 2027-04-20
Conditions
Breast Cancer, Early Breast Cancer
Interventions
DRUG
No Results Yet
NCT05770518 | COMPLETED | NA
51 Participants

Biofeedback vs Laryngeal Control Therapy in Management of Paradoxical Vocal Fold Motion

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2023-03-07
Completion: 2024-06-30
Conditions
Paradoxical Vocal Fold Motion Vocal Cord Dysfunction
Interventions
BEHAVIORAL
No Results Yet
NCT05768165 | ACTIVE_NOT_RECRUITING | NA
87 Participants

High-intensity Interval Exercise in Rheumatoid Arthritis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2021-08-16
Completion: 2023-06-30
Conditions
Rheumatoid Arthritis
Interventions
BEHAVIORAL
No Results Yet
NCT05767034 | ACTIVE_NOT_RECRUITING | PHASE3
381 Participants

Phase III Study of Efficacy and Safety of Secukinumab Versus Placebo, in Combination With Glucocorticoid Taper Regimen, in Patients With Polymyalgia Rheumatica (PMR)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2023-03-22
Completion: 2025-09-10
Conditions
Polymyalgia Rheumatica
Interventions
DRUG OTHER
No Results Yet
NCT05761171 | ACTIVE_NOT_RECRUITING | PHASE2
78 Participants

A Study of Revumenib in Combination With Chemotherapy for Patients Diagnosed With Relapsed or Refractory Leukemia

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2024-01-08
Completion: 2027-12-31
Conditions
Recurrent Acute Leukemia of Ambiguous Lineage Recurrent Acute Lymphoblastic Leukemia Recurrent Acute Myeloid Leukemia Due to Lineage Switch From Acute Leukemia of Ambiguous Lineage Recurrent Acute Myeloid Leukemia Due to Lineage Switch From B Acute Lymphoblastic Leukemia, KMT2A-Rearranged Recurrent Acute Myeloid Leukemia Due to Lineage Switch From Mixed Phenotype Acute Leukemia Recurrent Mixed Phenotype Acute Leukemia Refractory Acute Leukemia of Ambiguous Lineage Refractory Acute Lymphoblastic Leukemia Refractory Acute Myeloid Leukemia Due to Lineage Switch From Acute Leukemia of Ambiguous Lineage Refractory Acute Myeloid Leukemia Due to Lineage Switch From B Acute Lymphoblastic Leukemia, KMT2A-Rearranged Refractory Acute Myeloid Leukemia Due to Lineage Switch From Mixed Phenotype Acute Leukemia Refractory Mixed Phenotype Acute Leukemia
Interventions
PROCEDURE DRUG
No Results Yet
NCT05758493 | RECRUITING | PHASE2
150 Participants

Characterizing Iodine-124 Evuzumitide (AT-01) in Systemic Amyloidosis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2023-01-10
Completion: 2027-12-10
Conditions
Amyloidosis Transthyretin Amyloidosis
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT05757401 | COMPLETED
286 Participants

Sleep Quality After Cesarean Delivery

Study Type: OBSERVATIONAL
Last Updated: 2025-12-22
Start Date: 2023-03-14
Completion: 2024-05-15
Conditions
Cesarean Section Complications Sleep Disturbance Perioperative Complication
No Results Yet
NCT05754957 | ACTIVE_NOT_RECRUITING | PHASE3
14194 Participants

A Study of Milvexian in Participants After a Recent Acute Coronary Syndrome

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2023-04-07
Completion: 2026-09-07
Conditions
Acute Coronary Syndrome
Interventions
DRUG OTHER
No Results Yet
NCT05750459 | COMPLETED | PHASE4
90 Participants

Pharmacokinetic Study of IV Artesunate to Treat Children With Severe Malaria

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2023-11-29
Completion: 2025-04-01
Conditions
Plasmodium Falciparum Infection
Interventions
DRUG
No Results Yet
NCT05742685 | ACTIVE_NOT_RECRUITING | NA
28 Participants

Refinement and Adaption of Reinforcement Learning to Personalize Behavioral Messaging for Healthy Habits

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2023-08-23
Completion: 2025-12-17
Conditions
Diabetes Mellitus, Type 2 Medication Adherence
Interventions
BEHAVIORAL
No Results Yet
NCT05734638 | ACTIVE_NOT_RECRUITING | NA
90 Participants

Stress and Blood Pressure Management for Caregivers

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2023-09-11
Completion: 2026-06-30
Conditions
Hypertension Stress, Psychological
Interventions
BEHAVIORAL
No Results Yet
NCT05720299 | COMPLETED | NA
110 Participants

A Clinical Study to Evaluate the Effects of Akkermansia Muciniphila and Berberine on Prediabetes Among Obese Subjects.

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2025-03-12
Completion: 2025-06-30
Conditions
Prediabetes
Interventions
DRUG
No Results Yet
NCT05718570 | ENROLLING_BY_INVITATION
400 Participants

A Study to Follow Patients With Adult Growth Hormone Deficiency (AGHD) Treated With Sogroya® for Long Term Safety Information

Study Type: OBSERVATIONAL
Last Updated: 2025-12-22
Start Date: 2023-02-03
Completion: 2032-12-15
Conditions
Adult Growth Hormone Deficiency
Interventions
DRUG
No Results Yet
NCT05711667 | RECRUITING | PHASE3
105 Participants

A Study of the Drug Letermovir as Prevention of Cytomegalovirus Infection After Stem Cell Transplant in Pediatric Patients

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2024-07-11
Completion: 2029-06-30
Conditions
Hematopoietic and Lymphoid Cell Neoplasm Malignant Solid Neoplasm
Interventions
PROCEDURE DRUG
No Results Yet
NCT05707663 | RECRUITING
40 Participants

Longitudinal Assessment of Brain Structure and Function in Juvenile-onset Huntington's Disease

Study Type: OBSERVATIONAL
Last Updated: 2025-12-22
Start Date: 2023-04-17
Completion: 2026-08-31
Conditions
Juvenile Huntington Disease Juvenile-Onset Huntington Disease
No Results Yet
NCT05705531 | RECRUITING
230 Participants

A Study About How Blood Cell Growth Patterns Relate to Heart Health After Treatment for Hodgkin Lymphoma

Study Type: OBSERVATIONAL
Last Updated: 2025-12-22
Start Date: 2023-08-18
Completion: 2028-10-01
Conditions
Cardiovascular Disorder Clonal Hematopoiesis Hodgkin Lymphoma
Interventions
PROCEDURE OTHER
No Results Yet
NCT05703113 | COMPLETED | NA
110 Participants

The Effect of the Education Given to Nursing Students With Web 2.0 Tools on the Level of Participation, Attitude, Interest and Motivation

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2022-10-18
Completion: 2023-01-15
Conditions
Educational Problems
Interventions
BEHAVIORAL
No Results Yet
NCT05702645 | RECRUITING
330 Participants

A Study to Learn More About the Health of Persons With Down Syndrome After Treatment for Acute Leukemia

Study Type: OBSERVATIONAL
Last Updated: 2025-12-22
Start Date: 2023-11-30
Completion: 2029-06-30
Conditions
B Acute Lymphoblastic Leukemia Associated With Down Syndrome Down Syndrome Myeloid Leukemia Associated With Down Syndrome
Interventions
PROCEDURE OTHER
No Results Yet
NCT05700916 | RECRUITING | EARLY_PHASE1
130 Participants

Evaluation of Milk Polar Lipids in Dyslipidemic Adults With Abdominal Obesity

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2023-10-20
Completion: 2026-05-31
Conditions
Dyslipidemias Obesity
Interventions
DRUG DIETARY_SUPPLEMENT
No Results Yet
NCT05697146 | ACTIVE_NOT_RECRUITING
1018 Participants

Ribociclib Real-world Treatment Patterns and Clinical Outcomes Among Women With HR+/HER2- Advanced or Metastatic Breast Cancer in France

Study Type: OBSERVATIONAL
Last Updated: 2025-12-22
Start Date: 2022-12-13
Completion: 2028-06-30
Conditions
Breast Cancer
Interventions
OTHER
No Results Yet
NCT05691231 | ENROLLING_BY_INVITATION
158 Participants

Long-Term Assessment of the Safety and Performance of the NuVasive Simplify Disc at Two Levels

Study Type: OBSERVATIONAL
Last Updated: 2025-12-22
Start Date: 2023-01-18
Completion: 2029-02-10
Conditions
Cervical Disc Disease Degenerative Disc Disease
Interventions
DEVICE
No Results Yet
NCT05677100 | RECRUITING | NA
295 Participants

Diuretics Alone vs. Aortix Endovascular Device for Acute Heart Failure

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2023-08-23
Completion: 2026-06-30
Conditions
Heart Failure Cardiorenal Syndrome Cardio-Renal Syndrome ADHF Heart Failure, Systolic Heart Failure, Diastolic Heart Failure; With Decompensation Heart Failure, Congestive
Interventions
DEVICE
No Results Yet
NCT05648214 | RECRUITING | PHASE1
156 Participants

A Trial to Learn if ALN-PNP is Safe and Well Tolerated in Healthy Adults and Adult Participants With Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2022-12-27
Completion: 2027-08-10
Conditions
Healthy Volunteers Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)
Interventions
DRUG
No Results Yet
NCT05643066 | COMPLETED | PHASE4
246 Participants

Esketamine-propofol Versus Propofol for Flexible Bronchoscopy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2022-12-07
Completion: 2023-12-18
Conditions
Postoperative Recovery
Interventions
DRUG
No Results Yet
NCT05642221 | COMPLETED
73 Participants

Functional Near-Infrared Spectroscopy (fNIRS) Combined With Diffuse Correlation Spectroscopy (DCS) in Neurocognitive Disease as Compared to Healthy Neurotypical Controls

Study Type: OBSERVATIONAL
Last Updated: 2025-12-22
Start Date: 2023-01-23
Completion: 2024-10-10
Conditions
Juvenile Neuronal Ceroid Lipofuscinosis Smith-Lemli-Opitz Syndrome Creatine Transporter Deficiency Niemann-Pick Disease Type C1
No Results Yet
NCT05624749 | RECRUITING | PHASE3
280 Participants

Phase 3 Study to Evaluate Ianalumab on Top of Standard-of-care Therapy in Patients With Systemic Lupus Erythematosus (SIRIUS-SLE 2)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2023-04-21
Completion: 2027-04-23
Conditions
Systemic Lupus Erythematosus
Interventions
DRUG
No Results Yet
NCT05612750 | RECRUITING | NA
1650 Participants

Comparative Effectiveness of Online 8-session CBT vs. 1-Session Empowered Relief for Chronic Pain - The PROGRESS Study

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2023-01-01
Completion: 2029-05-01
Conditions
Pain, Chronic Lupus Pelvic Pain
Interventions
BEHAVIORAL
No Results Yet
NCT05611931 | RECRUITING | PHASE3
276 Participants

Selinexor in Maintenance Therapy After Systemic Therapy for Participants With p53 Wild-Type, Advanced or Recurrent Endometrial Carcinoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2023-04-18
Completion: 2026-08-31
Conditions
Endometrial Cancer
Interventions
DRUG
No Results Yet
NCT05602194 | RECRUITING | PHASE3
440 Participants

Studying the Effect of Levocarnitine in Protecting the Liver From Chemotherapy for Leukemia or Lymphoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2023-08-24
Completion: 2028-06-30
Conditions
B Acute Lymphoblastic Leukemia B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1 B Acute Lymphoblastic Leukemia, BCR-ABL1-Like Lymphoblastic Lymphoma Mixed Phenotype Acute Leukemia T Acute Lymphoblastic Leukemia
Interventions
PROCEDURE DRUG DIETARY_SUPPLEMENT OTHER
No Results Yet
NCT05582551 | RECRUITING | NA
146 Participants

Patients At Risk for Sensory Screening (HPARSS) to Enhance Sensory Deficit Screening in Childhood Cancer Survivors

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2023-08-02
Completion: 2026-05-31
Conditions
Childhood Cancer
Interventions
OTHER
No Results Yet
NCT05581004 | RECRUITING | PHASE1
450 Participants

A Study to Evaluate the Safety, Pharmacokinetics, and Activity of RO7502175 as a Single Agent and in Combination With Checkpoint Inhibitor in Participants With Locally Advanced or Metastatic Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2022-10-20
Completion: 2027-02-28
Conditions
Locally Advanced or Metastatic Solid Tumors NSCLC HNSCC Melanoma TNBC Esophageal Cancer Gastric Cancer Cervical Cancer Colorectal Cancer Urothelial Carcinoma Clear Cell RCC HCC
Interventions
DRUG
No Results Yet
NCT05580458 | RECRUITING | PHASE1/PHASE2
225 Participants

Safety and Immunogenicity of Recombinant Varicella Zoster Virus Vaccine in People With HIV Who Have a CD4 Count Less Than 300 or Greater Than or Equal to 300 and a Healthy Control Population

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2023-03-13
Completion: 2027-02-01
Conditions
Herpes Zoster
Interventions
BIOLOGICAL
No Results Yet
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