Patients At Risk for Sensory Screening (HPARSS) to Enhance Sensory Deficit Screening in Childhood Cancer Survivors

NCT ID: NCT05582551

Last Updated: 2025-12-22

Basic Information

• Recruitment Status: RECRUITING
• Clinical Phase: NA
• Total Enrollment: 146 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2023-08-02
• Study Completion Date: 2026-05-31

Brief Summary

The overall goal of this study is to attempt to overcome the organizational barriers that impede prompt screening for at-risk sensory deficits in childhood cancer survivors (CCS). Using a cross sectional design study, collaborators in the Informatics Research branch of the Institute of Informatics at the Washington University School of Medicine will identify CCS at risk for sensory deficits based upon their therapy exposure to generate the highlighting patients at risk for sensory screening (HPARSS) document. The investigators will utilize the HPARSS that will link therapy related risks for sensory deficits to specific screening procedures prompting the primary oncology provider to implement screening, diagnostic testing, and therapy.

Conditions

Childhood Cancer

Keywords

childhood cancer survivors; electronic medical record; sensory deficit screening; hearing loss; peripheral neuropathy; vestibular; vision

Study Design

• Allocation Method: NON_RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: HEALTH_SERVICES_RESEARCH
• Blinding Strategy: NONE

Study Groups

Patients: Highlighting Patients at Risk for Sensory Screening (HPARSS)

• The primary oncology team will utilize the HPARSS to identify patients who are at risk for sensory deficits based on prior treatment. The HPARSS will constitute a file of that will contain eligible patients based upon their past treatment and their corresponding risk for a particular sensory deficit based upon that treatment. The patient and parent/guardian will be approached to participate in the study.
• Sensory deficit screening will be completed in the clinic and any screening results that indicate the need for referral for diagnostic testing or therapy will be scheduled by the primary treatment team staff.

Group Type: EXPERIMENTAL

Highlighting Patients at Risk for Sensory Screening (HPARSS)

Intervention Type: OTHER

Collaborators in the Informatics Research branch of the Institute of Informatics at the Washington University School of Medicine will identify CCS at risk for sensory deficits based upon their therapy exposure to generate the HPARSS document.

Providers: Highlighting Patients at Risk for Sensory Screening (HPARSS)

-Providers will complete a survey regarding their views of the HPARSS. The Acceptability of Intervention Measure has 4 questions and the Feasibility of Intervention Measure has 4 questions.

Group Type: NO_INTERVENTION

No interventions assigned to this group

Interventions

Highlighting Patients at Risk for Sensory Screening (HPARSS)

Collaborators in the Informatics Research branch of the Institute of Informatics at the Washington University School of Medicine will identify CCS at risk for sensory deficits based upon their therapy exposure to generate the HPARSS document.

Intervention Type: OTHER

Eligibility Criteria

Inclusion Criteria

• Patients with a diagnosis of pediatric cancer (diagnosis at <18 years of age)
• Treatment including chemotherapy and/or radiation therapy
• Completion of all cancer therapy for at least 6 months and less than 2 years
• Followed in the Division of Pediatric Hematology/Oncology Program at the Washington University School of Medicine
• Current age between 7 and 17 years of age (age where all of the screening tests are both valid and have been successfully performed by our group)
• English speaking

Exclusion Criteria

• Undergoing active cancer treatment
• Patient under the care of the Late Effects Program at St. Louis Children's Hospital
• Received previous diagnostic testing or rehabilitative therapy for a secondary deficit eligible for screening.
• Parents and/or patient illiteracy
• No contact with treatment team in the past two years
• In foster care or without a legal guardian

• Minimum Eligible Age: 7 Years
• Maximum Eligible Age: 17 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

St. Jude Children's Research Hospital

OTHER

Sponsor Role: collaborator

Washington University School of Medicine

OTHER

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Principal Investigators

Robert J Hayashi, M.D.

Role: PRINCIPAL_INVESTIGATOR

Washington University School of Medicine

Locations

St. Louis Children's Hospital - Washington University School of Medicine

St Louis, Missouri, United States

Site Status: RECRUITING

Countries

United States

Central Contacts

Robert J Hayashi, M.D.

Role: CONTACT

Phone: 314-454-6018

Email: hayashi_r@wustl.edu

Facility Contacts

Robert J Hayashi, M.D.

Role: primary

Related Links

http://www.siteman.wustl.edu

Alvin J. Siteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine

Other Identifiers

202208066

Identifier Type: -

Identifier Source: org_study_id