Clinical Trials
Showing trials with last updates posted in 2025.
381
Participants
Phase III Study of Efficacy and Safety of Secukinumab Versus Placebo, in Combination With Glucocorticoid Taper Regimen, in Patients With Polymyalgia Rheumatica (PMR)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2023-03-22
Completion:
2025-09-10
Conditions
Polymyalgia Rheumatica
Interventions
DRUG
OTHER
No Results Yet
78
Participants
A Study of Revumenib in Combination With Chemotherapy for Patients Diagnosed With Relapsed or Refractory Leukemia
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2024-01-08
Completion:
2027-12-31
Conditions
Recurrent Acute Leukemia of Ambiguous Lineage
Recurrent Acute Lymphoblastic Leukemia
Recurrent Acute Myeloid Leukemia Due to Lineage Switch From Acute Leukemia of Ambiguous Lineage
Recurrent Acute Myeloid Leukemia Due to Lineage Switch From B Acute Lymphoblastic Leukemia, KMT2A-Rearranged
Recurrent Acute Myeloid Leukemia Due to Lineage Switch From Mixed Phenotype Acute Leukemia
Recurrent Mixed Phenotype Acute Leukemia
Refractory Acute Leukemia of Ambiguous Lineage
Refractory Acute Lymphoblastic Leukemia
Refractory Acute Myeloid Leukemia Due to Lineage Switch From Acute Leukemia of Ambiguous Lineage
Refractory Acute Myeloid Leukemia Due to Lineage Switch From B Acute Lymphoblastic Leukemia, KMT2A-Rearranged
Refractory Acute Myeloid Leukemia Due to Lineage Switch From Mixed Phenotype Acute Leukemia
Refractory Mixed Phenotype Acute Leukemia
Interventions
PROCEDURE
DRUG
No Results Yet
150
Participants
Characterizing Iodine-124 Evuzumitide (AT-01) in Systemic Amyloidosis
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2023-01-10
Completion:
2027-12-10
Conditions
Amyloidosis
Transthyretin Amyloidosis
Interventions
DIAGNOSTIC_TEST
No Results Yet
286
Participants
Sleep Quality After Cesarean Delivery
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-22
Start Date:
2023-03-14
Completion:
2024-05-15
Conditions
Cesarean Section Complications
Sleep Disturbance
Perioperative Complication
No Results Yet
14194
Participants
A Study of Milvexian in Participants After a Recent Acute Coronary Syndrome
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2023-04-07
Completion:
2026-09-07
Conditions
Acute Coronary Syndrome
Interventions
DRUG
OTHER
No Results Yet
90
Participants
Pharmacokinetic Study of IV Artesunate to Treat Children With Severe Malaria
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2023-11-29
Completion:
2025-04-01
Conditions
Plasmodium Falciparum Infection
Interventions
DRUG
No Results Yet
28
Participants
Refinement and Adaption of Reinforcement Learning to Personalize Behavioral Messaging for Healthy Habits
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2023-08-23
Completion:
2025-12-17
Conditions
Diabetes Mellitus, Type 2
Medication Adherence
Interventions
BEHAVIORAL
No Results Yet
110
Participants
A Clinical Study to Evaluate the Effects of Akkermansia Muciniphila and Berberine on Prediabetes Among Obese Subjects.
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2025-03-12
Completion:
2025-06-30
Conditions
Prediabetes
Interventions
DRUG
No Results Yet
400
Participants
A Study to Follow Patients With Adult Growth Hormone Deficiency (AGHD) Treated With Sogroya® for Long Term Safety Information
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-22
Start Date:
2023-02-03
Completion:
2032-12-15
Conditions
Adult Growth Hormone Deficiency
Interventions
DRUG
No Results Yet
105
Participants
A Study of the Drug Letermovir as Prevention of Cytomegalovirus Infection After Stem Cell Transplant in Pediatric Patients
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2024-07-11
Completion:
2029-06-30
Conditions
Hematopoietic and Lymphoid Cell Neoplasm
Malignant Solid Neoplasm
Interventions
PROCEDURE
DRUG
No Results Yet
40
Participants
Longitudinal Assessment of Brain Structure and Function in Juvenile-onset Huntington's Disease
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-22
Start Date:
2023-04-17
Completion:
2026-08-31
Conditions
Juvenile Huntington Disease
Juvenile-Onset Huntington Disease
No Results Yet
230
Participants
A Study About How Blood Cell Growth Patterns Relate to Heart Health After Treatment for Hodgkin Lymphoma
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-22
Start Date:
2023-08-18
Completion:
2028-10-01
Conditions
Cardiovascular Disorder
Clonal Hematopoiesis
Hodgkin Lymphoma
Interventions
PROCEDURE
OTHER
No Results Yet
110
Participants
The Effect of the Education Given to Nursing Students With Web 2.0 Tools on the Level of Participation, Attitude, Interest and Motivation
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2022-10-18
Completion:
2023-01-15
Conditions
Educational Problems
Interventions
BEHAVIORAL
No Results Yet
330
Participants
A Study to Learn More About the Health of Persons With Down Syndrome After Treatment for Acute Leukemia
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-22
Start Date:
2023-11-30
Completion:
2029-06-30
Conditions
B Acute Lymphoblastic Leukemia Associated With Down Syndrome
Down Syndrome
Myeloid Leukemia Associated With Down Syndrome
Interventions
PROCEDURE
OTHER
No Results Yet
130
Participants
Evaluation of Milk Polar Lipids in Dyslipidemic Adults With Abdominal Obesity
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2023-10-20
Completion:
2026-05-31
Conditions
Dyslipidemias
Obesity
Interventions
DRUG
DIETARY_SUPPLEMENT
No Results Yet
1018
Participants
Ribociclib Real-world Treatment Patterns and Clinical Outcomes Among Women With HR+/HER2- Advanced or Metastatic Breast Cancer in France
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-22
Start Date:
2022-12-13
Completion:
2028-06-30
Conditions
Breast Cancer
Interventions
OTHER
No Results Yet
158
Participants
Long-Term Assessment of the Safety and Performance of the NuVasive Simplify Disc at Two Levels
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-22
Start Date:
2023-01-18
Completion:
2029-02-10
Conditions
Cervical Disc Disease
Degenerative Disc Disease
Interventions
DEVICE
No Results Yet
295
Participants
Diuretics Alone vs. Aortix Endovascular Device for Acute Heart Failure
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2023-08-23
Completion:
2026-06-30
Conditions
Heart Failure
Cardiorenal Syndrome
Cardio-Renal Syndrome
ADHF
Heart Failure, Systolic
Heart Failure, Diastolic
Heart Failure; With Decompensation
Heart Failure, Congestive
Interventions
DEVICE
No Results Yet
156
Participants
A Trial to Learn if ALN-PNP is Safe and Well Tolerated in Healthy Adults and Adult Participants With Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2022-12-27
Completion:
2027-08-10
Conditions
Healthy Volunteers
Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)
Interventions
DRUG
No Results Yet
246
Participants
Esketamine-propofol Versus Propofol for Flexible Bronchoscopy
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2022-12-07
Completion:
2023-12-18
Conditions
Postoperative Recovery
Interventions
DRUG
No Results Yet
73
Participants
Functional Near-Infrared Spectroscopy (fNIRS) Combined With Diffuse Correlation Spectroscopy (DCS) in Neurocognitive Disease as Compared to Healthy Neurotypical Controls
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-22
Start Date:
2023-01-23
Completion:
2024-10-10
Conditions
Juvenile Neuronal Ceroid Lipofuscinosis
Smith-Lemli-Opitz Syndrome
Creatine Transporter Deficiency
Niemann-Pick Disease Type C1
No Results Yet
280
Participants
Phase 3 Study to Evaluate Ianalumab on Top of Standard-of-care Therapy in Patients With Systemic Lupus Erythematosus (SIRIUS-SLE 2)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2023-04-21
Completion:
2027-04-23
Conditions
Systemic Lupus Erythematosus
Interventions
DRUG
No Results Yet
1650
Participants
Comparative Effectiveness of Online 8-session CBT vs. 1-Session Empowered Relief for Chronic Pain - The PROGRESS Study
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2023-01-01
Completion:
2029-05-01
Conditions
Pain, Chronic
Lupus
Pelvic Pain
Interventions
BEHAVIORAL
No Results Yet
276
Participants
Selinexor in Maintenance Therapy After Systemic Therapy for Participants With p53 Wild-Type, Advanced or Recurrent Endometrial Carcinoma
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2023-04-18
Completion:
2026-08-31
Conditions
Endometrial Cancer
Interventions
DRUG
No Results Yet
440
Participants
Studying the Effect of Levocarnitine in Protecting the Liver From Chemotherapy for Leukemia or Lymphoma
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2023-08-24
Completion:
2028-06-30
Conditions
B Acute Lymphoblastic Leukemia
B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1
B Acute Lymphoblastic Leukemia, BCR-ABL1-Like
Lymphoblastic Lymphoma
Mixed Phenotype Acute Leukemia
T Acute Lymphoblastic Leukemia
Interventions
PROCEDURE
DRUG
DIETARY_SUPPLEMENT
OTHER
No Results Yet
146
Participants
Patients At Risk for Sensory Screening (HPARSS) to Enhance Sensory Deficit Screening in Childhood Cancer Survivors
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2023-08-02
Completion:
2026-05-31
Conditions
Childhood Cancer
Interventions
OTHER
No Results Yet
450
Participants
A Study to Evaluate the Safety, Pharmacokinetics, and Activity of RO7502175 as a Single Agent and in Combination With Checkpoint Inhibitor in Participants With Locally Advanced or Metastatic Solid Tumors
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2022-10-20
Completion:
2027-02-28
Conditions
Locally Advanced or Metastatic Solid Tumors
NSCLC
HNSCC
Melanoma
TNBC
Esophageal Cancer
Gastric Cancer
Cervical Cancer
Colorectal Cancer
Urothelial Carcinoma
Clear Cell RCC
HCC
Interventions
DRUG
No Results Yet
225
Participants
Safety and Immunogenicity of Recombinant Varicella Zoster Virus Vaccine in People With HIV Who Have a CD4 Count Less Than 300 or Greater Than or Equal to 300 and a Healthy Control Population
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2023-03-13
Completion:
2027-02-01
Conditions
Herpes Zoster
Interventions
BIOLOGICAL
No Results Yet
20
Participants
Assessment of the Efficacy and Safety of Alpelisib (BYL719) in Pediatric and Adult Patients With Megalencephaly-CApillary Malformation Polymicrogyria Syndrome (MCAP)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2022-11-28
Completion:
2027-03-31
Conditions
Megalencephaly-capillary Malformation Polymicrogyria Syndrome (MCAP)
Interventions
DRUG
PROCEDURE
No Results Yet
150
Participants
Otoferlin Gene-mediated Hearing Loss Natural History Study
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-22
Start Date:
2022-07-14
Completion:
2029-02-28
Conditions
Sensorineural Hearing Loss, Bilateral
Interventions
OTHER
No Results Yet
40
Participants
Deucravacitinib Adherence Study
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2023-07-24
Completion:
2026-03-31
Conditions
Psoriasis
Interventions
BEHAVIORAL
No Results Yet
30
Participants
Depression, Aging, Stress and Heart Health Study
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2022-11-16
Completion:
2026-06-30
Conditions
Menopause
Depression
Heart Disease in Women
Stress
Interventions
BEHAVIORAL
No Results Yet
840
Participants
Evaluation of the Superiority of VAsopressin Versus NOradrenaline in the Management of Patients at Risk of Kidney Failure Undergoing Cardiac Surgery With Extracorporeal Circulation
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2023-01-02
Completion:
2026-03-31
Conditions
Scheduled Cardiac Surgery With Extracorporeal Circulation
Vasoplegic Syndrome
Interventions
DRUG
OTHER
No Results Yet
123
Participants
Retrospective Modulus ALIF Study
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-22
Start Date:
2022-08-18
Completion:
2022-10-15
Conditions
Degenerative Disc Disease
Spondylolisthesis
Stenosis
Interventions
DEVICE
No Results Yet
123
Participants
Effect of Oral Nutritional Supplements to Older Patients Discharged With a Rehabilitation Plan
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2023-12-01
Completion:
2026-03-30
Conditions
Nutritional Risk
Rehabilitation
Oral Nutritional Supplements
Interventions
DIETARY_SUPPLEMENT
No Results Yet
34
Participants
Study of BD Sirolimus Drug Coated Catheter for Treatment of Femoropopliteal Arteries
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2022-08-02
Completion:
2024-06-12
Conditions
Peripheral Arterial Disease
Peripheral Artery Disease
Stenosis Artery
Interventions
DEVICE
No Results Yet
150
Participants
Resources, Inspiration, Support and Empowerment (RISE) for Black Pregnant Women
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2023-06-01
Completion:
2026-06-01
Conditions
Stress, Psychological
Racism
Discrimination, Racial
Inflammation
Pregnancy Related
Pregnancy Complications
Pregnancy, High Risk
Depression
Depression, Postpartum
Perinatal Depression
Anxiety
Anxiety in Pregnancy
Interventions
DEVICE
No Results Yet
120
Participants
Safety and Immune Responses After Vaccination With Two Investigational RNA-based Vaccines Against Tuberculosis in Healthy Volunteers
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2023-04-18
Completion:
2025-06-06
Conditions
Tuberculosis
Interventions
BIOLOGICAL
OTHER
No Results Yet
38
Participants
BrainWeighve App Feasibility Study
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2023-11-01
Completion:
2026-12-31
Conditions
Weight Loss
Obesity and Overweight
Interventions
BEHAVIORAL
No Results Yet
1753
Participants
Lung Volume Preservation During Extubation
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2023-01-15
Completion:
2024-08-13
Conditions
Weaning Failure
Pulmonary Collapse
Interventions
OTHER
No Results Yet
Showing 40 trials per page