Clinical Trials
Showing trials with last updates posted in 2025.
88
Participants
Improving Family Quality of Life Through Training to Reduce Care-Resistant Behaviors by People With AD and TBI
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2017-02-01
Completion:
2019-08-21
Conditions
Dementia
Traumatic Brain Injury
Interventions
BEHAVIORAL
No Results Yet
100
Participants
Home Exercise vs PT for Reverse Total Shoulder Arthroplasty
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2019-01-22
Completion:
2025-08-11
Conditions
Shoulder Arthritis
Rotator Cuff Tear Arthropathy
Interventions
OTHER
No Results Yet
1397
Participants
Efficacy and Safety of Pembrolizumab (MK-3475) in Combination With Bacillus Calmette-Guerin (BCG) in High-Risk Non-Muscle Invasive Bladder Cancer (HR NMIBC) (MK-3475-676/KEYNOTE-676)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2018-12-24
Completion:
2026-07-31
Conditions
High-risk Non-muscle Invasive Bladder Cancer
Interventions
BIOLOGICAL
No Results Yet
40
Participants
Influence of Obesity on Endogenous Oxalate Synthesis
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2019-05-24
Completion:
2026-03-31
Conditions
Kidney Stone
Interventions
DIETARY_SUPPLEMENT
No Results Yet
104
Participants
Efficacy of the Nurtured Heart Approach to Reduce ADHD Behaviors in Children
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2017-08-14
Completion:
2018-06-30
Conditions
Attention Deficit Hyperactivity Disorder
Interventions
BEHAVIORAL
No Results Yet
1010
Participants
Early Versus Differed Arterial Catheterization in Critically Ill Patients With Acute Circulatory Failure:
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2018-11-15
Completion:
2022-11-29
Conditions
Acute Circulatory Failure
Interventions
PROCEDURE
No Results Yet
300
Participants
Advanced Materials Science in XLIF Study
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-22
Start Date:
2018-08-19
Completion:
2026-06-30
Conditions
Degenerative Disc Disease
Spondylolisthesis
No Results Yet
36
Participants
NSAIDs Stent Study
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2018-07-31
Completion:
2026-10-31
Conditions
Ureteral Stent Placement
Kidney Stone
Interventions
DRUG
No Results Yet
45
Participants
Pembrolizumab in Preventing Lung Cancer in Patients With Stage I-II Non-Small Cell Lung Cancer or High-Risk Pulmonary Nodules, the IMPRINT-Lung Study
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2018-11-13
Completion:
2026-02-28
Conditions
Lung Non-Small Cell Carcinoma
Stage I Lung Cancer AJCC v8
Stage IA1 Lung Cancer AJCC v8
Stage IA2 Lung Cancer AJCC v8
Stage IA3 Lung Cancer AJCC v8
Stage IB Lung Cancer AJCC v8
Stage II Lung Cancer AJCC v8
Stage IIA Lung Cancer AJCC v8
Stage IIB Lung Cancer AJCC v8
Interventions
BIOLOGICAL
OTHER
PROCEDURE
No Results Yet
21
Participants
REACTION (Radiation Enhanced Assessment of Combination Therapies in Immuno-ONcology) - Nivolumab or Nivolumab in Combination With Other Immuno-oncology (IO) Agents After Targeted Systemic Radiation in Patients With Advanced Esophagogastric Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2019-03-06
Completion:
2026-04-30
Conditions
Gastroesophageal Cancer
Immune Checkpoint Inhibition
Interventions
DRUG
No Results Yet
11
Participants
Study to Test the Safety and How Well Patients With Severe Hemophilia A Respond to Treatment With BAY 2599023 (DTX 201), a Drug Therapy That Delivers a Healthy Version of the Defective Factor VIII Gene Into the Nucleus of Liver Cells Using an Altered, Non-infectious Virus (AAV) as a "Shuttle"
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2018-11-07
Completion:
2026-11-03
Conditions
Hemophilia A
Interventions
DRUG
No Results Yet
76
Participants
Pilot Study of the Liver Live Donor Champion Program
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2018-09-18
Completion:
2025-11-28
Conditions
End Stage Liver Disease
Interventions
BEHAVIORAL
No Results Yet
40
Participants
Shaving Satisfaction in Males With Skin Irritation From Shaving
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2018-10-29
Completion:
2019-04-30
Conditions
Pseudofolliculitis Barbae
Interventions
OTHER
No Results Yet
175
Participants
Clinical Prognosis of Patients With Atrial Fibrillation During Radiofrequency Ablation
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2019-02-14
Completion:
2023-02-09
Conditions
Atrial Fibrillation
Interventions
PROCEDURE
No Results Yet
96
Participants
Imaging Histone Deacetylase in the Heart
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2018-09-07
Completion:
2026-03-01
Conditions
Heart Failure With Normal Ejection Fraction
Left Ventricular Hypertrophy
Aortic Valve Stenosis
Diabetes
Interventions
DRUG
DEVICE
No Results Yet
537
Participants
Cisplatin and Combination Chemotherapy in Treating Children and Young Adults With Hepatoblastoma or Liver Cancer After Surgery
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2018-05-24
Completion:
2026-12-31
Conditions
Childhood Hepatocellular Carcinoma
Childhood Malignant Liver Neoplasm
Fibrolamellar Carcinoma
Hepatoblastoma
Hepatocellular Malignant Neoplasm, Not Otherwise Specified
Interventions
PROCEDURE
DRUG
OTHER
No Results Yet
1490
Participants
Evaluation of a Home-based Community Health Worker Program in Rural Eastern Cape, South Africa
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-22
Start Date:
2014-08-11
Completion:
2018-06-01
Conditions
Alcohol; Harmful Use
Child Development
Child Malnutrition
Child Nutrition Disorders
Birth Weight Less Than 10Th Percentile
Depression
Depressive Symptoms
Alcohol Use Disorder
Alcohol Drinking
Stunting
HIV Infections
HIV/AIDS
Interventions
BEHAVIORAL
No Results Yet
26
Participants
Spinal Cord Injury Exercise and Nutrition Conceptual Engagement
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2021-06-10
Completion:
2024-07-24
Conditions
Spinal Cord Injuries
Metabolic Syndrome
Dietary Modification
Paraplegia
Tetraplegia
Interventions
DEVICE
BEHAVIORAL
280
Participants
Project BIPAMS: Behavioral Intervention for Physical Activity in Multiple Sclerosis
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2018-03-01
Completion:
2023-03-01
Conditions
Multiple Sclerosis
Interventions
BEHAVIORAL
No Results Yet
1409
Participants
A Study of the Efficacy and Safety of Guselkumab in Participants With Moderately to Severely Active Crohn's Disease
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2018-04-13
Completion:
2023-10-20
Conditions
Crohn's Disease
Interventions
DRUG
30
Participants
Usability of SMART ANGEL Medical Device to Record and Transmit Health Data From Patient's Home Following Outpatient Surgery
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2018-05-14
Completion:
2018-09-30
Conditions
Surgery
Interventions
DEVICE
No Results Yet
211
Participants
A Study of the Combination of Ibrutinib Plus Venetoclax Versus Chlorambucil Plus Obinutuzumab for the First-line Treatment of Participants With Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2018-04-17
Completion:
2021-02-26
Conditions
Leukemia, Lymphocytic, Chronic, B-Cell
Interventions
DRUG
111
Participants
Implementation of the Live Donor Champion Program
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2018-05-30
Completion:
2025-03-30
Conditions
End-stage Renal Disease
Interventions
BEHAVIORAL
No Results Yet
792
Participants
A Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Patients With Metastatic or Locally Advanced Breast Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2018-03-30
Completion:
2030-09-30
Conditions
Metastatic Breast Cancer
Interventions
DRUG
No Results Yet
180
Participants
A Study to Assess the Safety and Tolerability of AZD1390 Given With Radiation Therapy in Patients With Brain Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2018-04-02
Completion:
2026-09-16
Conditions
Recurrent Glioblastoma Multiforme
Primary Glioblastoma Multiforme
Brain Neoplasms, Malignant
Leptomeningeal Disease (LMD)
Interventions
RADIATION
DRUG
No Results Yet
629
Participants
A Study of Erdafitinib Compared With Vinflunine or Docetaxel or Pembrolizumab in Participants With Advanced Urothelial Cancer and Selected Fibroblast Growth Factor Receptor (FGFR) Gene Aberrations
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2018-03-23
Completion:
2024-04-15
Conditions
Urothelial Cancer
Interventions
DRUG
DEVICE
147
Participants
Spreading Depolarizations in Traumatic Brain Injury
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-22
Start Date:
2017-03-28
Completion:
2021-06-15
Conditions
Traumatic Brain Injury
No Results Yet
105
Participants
Study of EGF816 in Combination With Selected Targeted Agents in EGFR-mutant NSCLC
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2018-01-29
Completion:
2026-03-09
Conditions
EGFR-mutant Non-small Cell Lung Cancer
Interventions
DRUG
No Results Yet
40
Participants
Anterior Capsulo-labral Reinsertion by Arthroscopic Approach Versus Immobilization
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2014-03-27
Completion:
2019-03-26
Conditions
Bankart Lesion
Interventions
PROCEDURE
No Results Yet
51
Participants
Patient-Centered Opioid Tapering Study
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-22
Start Date:
2015-09-15
Completion:
2017-08-10
Conditions
Opioid Use
Chronic Pain
Interventions
OTHER
No Results Yet
20
Participants
Phase II Study of Pembrolizumab and Lenvatinib in Advanced Well-differentiated Neuroendocrine Tumors
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2017-12-15
Completion:
2023-01-10
Conditions
Neuroendocrine Tumors
Neuroendocrine Carcinoma
Neuroendocrine Cancer
Interventions
DRUG
120
Participants
CDK 4/6 Inhibitor, Ribociclib, With Adjuvant Endocrine Therapy for ER-positive Breast Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2017-12-12
Completion:
2026-04-30
Conditions
Breast Cancer
Interventions
DRUG
OTHER
No Results Yet
186
Participants
Management of Pain Post Hepatectomy : Infiltration of Local Anesthetics Versus Continuous Spinal Analgesia .
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2015-05-20
Completion:
2019-05-25
Conditions
Pain, Postoperative
Interventions
DRUG
No Results Yet
288
Participants
Diagnosing Clinically Significant Prostate Cancer In African American and White Men With Elevated PSA
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2017-09-25
Completion:
2026-06-30
Conditions
Health Status Unknown
Elevated PSA
Interventions
PROCEDURE
OTHER
DIAGNOSTIC_TEST
No Results Yet
68
Participants
ADCC Mediated B-Cell dEpletion and BAFF-R Blockade
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2018-02-15
Completion:
2023-12-28
Conditions
Autoimmune Hepatitis
Interventions
BIOLOGICAL
OTHER
No Results Yet
61
Participants
Study to Assess the Efficacy, Safety and Tolerability of MT- 8554 in Subjects With Painful Diabetic Peripheral Neuropathy
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2017-07-25
Completion:
2018-08-08
Conditions
Painful Diabetic Peripheral Neuropathy
Interventions
DRUG
No Results Yet
850
Participants
Study Comparing Inhaled Amikacin Versus Placebo to Prevent Ventilator Associated Pneumonia
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2017-07-19
Completion:
2021-03-09
Conditions
Pneumonia, Ventilator-Associated
Interventions
DRUG
No Results Yet
750
Participants
Testing the Addition of 131I-MIBG or Lorlatinib to Intensive Therapy in People With High-Risk Neuroblastoma (NBL)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2018-05-14
Completion:
2030-09-30
Conditions
Ganglioneuroblastoma
Ganglioneuroblastoma, Nodular
Neuroblastoma
Interventions
PROCEDURE
DRUG
BIOLOGICAL
RADIATION
No Results Yet
340
Participants
Osseointegration of THA Grafted by PolyNASS (ACTISURF-CERAFIT® ) Versus Non-grafted THA (CERAFIT®)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2017-05-08
Completion:
2024-12-31
Conditions
Osteoarthritis, Hip
Coxarthrosis; Primary
Coxarthrosis; Secondary
Osteonecrosis; Aseptic, Idiopathic
Hip Arthroplasty Replacement
Hip Arthroplasty, Total
Hip Arthroplasty
Interventions
DEVICE
No Results Yet
76
Participants
Pembrolizumab With Carboplatin Compared to Carboplatin Alone in Breast Cancer Patients With Chest Wall Disease
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-22
Start Date:
2017-09-02
Completion:
2024-11-30
Conditions
Breast Cancer
Chest Wall Disease
Interventions
BIOLOGICAL
DRUG
Showing 40 trials per page