Clinical Trials

Showing trials with last updates posted in 2025.

NCT06013969 | ACTIVE_NOT_RECRUITING | PHASE4
42 Participants

A Study to Test Whether Spesolimab Helps People With Generalized Pustular Psoriasis (GPP) Who Need Treatment for Repeated Flares

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2023-10-22
Completion: 2026-07-23
Conditions
Generalized Pustular Psoriasis
Interventions
DRUG
No Results Yet
NCT06008145 | ACTIVE_NOT_RECRUITING
568 Participants

COPD Case Finding In Nottingham and District: C-FIND COPD A Pilot Study

Study Type: OBSERVATIONAL
Last Updated: 2025-12-19
Start Date: 2023-09-21
Completion: 2025-12-31
Conditions
COPD
No Results Yet
NCT06006117 | RECRUITING | PHASE3
260 Participants

Mosunetuzumab-Lenalidomide Versus Investigator Choices in Patients With Relapsed or Refractory Marginal Zone Lymphoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2023-09-05
Completion: 2027-09-30
Conditions
Marginal Zone Lymphoma
Interventions
DRUG
No Results Yet
NCT05991284 | ACTIVE_NOT_RECRUITING | PHASE4
84 Participants

Sacubitril-Valsartan in Heart Failure With Preserved Ejection Fraction and Secondary Mitral Valve Regurgitation

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2024-02-29
Completion: 2025-09-22
Conditions
Heart Failure With Preserved Ejection Fraction Functional Mitral Regurgitation
Interventions
DRUG
No Results Yet
NCT05986188 | ACTIVE_NOT_RECRUITING
111 Participants

Evaluating a School-based Social and Material Needs Identification System to Prevent Youth Violence Involvement

Study Type: OBSERVATIONAL
Last Updated: 2025-12-19
Start Date: 2024-02-21
Completion: 2025-10-01
Conditions
Violence, Physical Maltreatment, Child
Interventions
OTHER
No Results Yet
NCT05973513 | ACTIVE_NOT_RECRUITING
25 Participants

Open Trial of Biofeedback for Respiratory Symptoms

Study Type: OBSERVATIONAL
Last Updated: 2025-12-19
Start Date: 2021-08-01
Completion: 2027-07-31
Conditions
Shortness of Breath/Dyspnea
No Results Yet
NCT05963074 | RECRUITING | PHASE2
320 Participants

A Study to Customize Ibrutinib Treatment Regimens for Participants With Previously Untreated Chronic Lymphocytic Leukemia

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2024-05-30
Completion: 2027-12-15
Conditions
Leukemia, Lymphocytic, Chronic, B-Cell Small Lymphocytic Lymphoma
Interventions
DRUG
No Results Yet
NCT05954494 | COMPLETED
21 Participants

Protection Response to Cellular Stress in BPAN's Patient Study

Study Type: OBSERVATIONAL
Last Updated: 2025-12-19
Start Date: 2023-10-23
Completion: 2025-10-23
Conditions
Children and Adults With BPAN Carrying Pathogenic Variants of WDR45
Interventions
BIOLOGICAL
No Results Yet
NCT05954481 | COMPLETED | NA
47 Participants

Stress-Echography in Hereditary Haemorrhagic Telangiectasia Patient With Hepatic Involvement

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2023-08-03
Completion: 2025-01-14
Conditions
Hereditary Hemorrhagic Telangiectasia Rendu Osler Disease
Interventions
OTHER
No Results Yet
NCT05953363 | COMPLETED
161 Participants

Prospective Clinical Evaluation of BD NRFitâ„¢ Devices and Accessories.

Study Type: OBSERVATIONAL
Last Updated: 2025-12-19
Start Date: 2023-07-24
Completion: 2024-05-28
Conditions
Anesthesia Analgesia
Interventions
DEVICE
NCT05947591 | COMPLETED
25 Participants

Influence of Gait and Running on Foot Posture

Study Type: OBSERVATIONAL
Last Updated: 2025-12-19
Start Date: 2023-06-20
Completion: 2023-06-20
Conditions
Foot Pronation in Healthy Adult
Interventions
BEHAVIORAL
No Results Yet
NCT05927207 | COMPLETED | NA
40 Participants

Pilot Testing of a Mobile Phone App-based Intervention for Parents of Children With Autism Spectrum Disorder (ASD)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2023-08-01
Completion: 2024-08-05
Conditions
Autism Spectrum Disorder Parent-Child Relations
Interventions
OTHER
No Results Yet
NCT05923073 | RECRUITING | PHASE3
120 Participants

A Study of Guselkumab in Pediatric Participants With Moderately to Severely Active Crohn's Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2024-03-13
Completion: 2027-10-27
Conditions
Crohn's Disease
Interventions
DRUG
No Results Yet
NCT05908734 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2
71 Participants

A Study of Combination Therapy With Amivantamab and Cetrelimab in Participants With Metastatic Non-small Cell Lung Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2023-05-18
Completion: 2026-01-30
Conditions
Carcinoma, Non-Small-Cell Lung
Interventions
DRUG
No Results Yet
NCT05906888 | COMPLETED
156 Participants

Weaning With Tracheostomy - an Observational Study on Patient-centered Outcomes

Study Type: OBSERVATIONAL
Last Updated: 2025-12-19
Start Date: 2023-05-08
Completion: 2024-11-30
Conditions
Weaning Failure Mechanical Ventilation Patient-centered Care
No Results Yet
NCT05906875 | COMPLETED | NA
5 Participants

A Novel Balance Program to Improve Balance in People With Parkinson's Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2023-09-20
Completion: 2023-12-18
Conditions
Rehabilitation Exercise Physical Therapy
Interventions
OTHER
No Results Yet
NCT05884398 | ACTIVE_NOT_RECRUITING | PHASE3
420 Participants

A Study of an Intermittent ADT Approach With Apalutamide Monotherapy in Participants With mCSPC

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2023-08-31
Completion: 2026-10-12
Conditions
Metastatic Castrate-sensitive Prostate Cancer
Interventions
DRUG
No Results Yet
NCT05877235 | COMPLETED | NA
60 Participants

Serum Concentration of Endogenous Estrogens and Sirtuin-1 After Administration of Atorvastatin and Quercetin:

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2021-10-03
Completion: 2023-12-23
Conditions
Coronary Artery Disease Menopause
Interventions
DIETARY_SUPPLEMENT
No Results Yet
NCT05868408 | RECRUITING | NA
234 Participants

Effect of Partially Hydrolyzed, Whey-based Infant Formulas on Growth and Tolerability in Healthy Term Infants

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2023-08-17
Completion: 2027-12-31
Conditions
Infant Nutritional Physiological Phenomena Infant Formula Infant Health Infant Development Growth and Development
Interventions
OTHER
No Results Yet
NCT05863754 | RECRUITING | NA
13 Participants

Grasp-Release Assessment of a Networked Neuroprosthesis Device

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2022-01-23
Completion: 2027-12-01
Conditions
Spinal Cord Injury at C5-C7 Level Spinal Cord Injuries Spinal Cord Injury Cervical
Interventions
DEVICE
No Results Yet
NCT05852353 | COMPLETED | NA
204 Participants

Impact, Feasibility, and Acceptability of Bladder Basics

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2023-08-22
Completion: 2024-11-10
Conditions
Health Knowledge, Attitudes, Practice
Interventions
OTHER
NCT05838573 | RECRUITING | PHASE3
120 Participants

Metformin Treatment on Cognitive Impairment of Schizophrenia

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2023-05-08
Completion: 2026-12-12
Conditions
Schizophrenia
Interventions
DRUG OTHER
No Results Yet
NCT05826119 | COMPLETED | NA
60 Participants

Intravenous Administration of Magnesium Sulfate in Laparoscopic Hysterectomy Cases

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2024-01-20
Completion: 2024-03-30
Conditions
Laparoscopic Hysterectomy Magnesium Sulfate General Anesthesia
Interventions
DRUG
No Results Yet
NCT05823142 | RECRUITING | NA
300 Participants

Health Behavior Intervention for Adults With Type 1 Diabetes

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2023-12-20
Completion: 2028-07-31
Conditions
Type1diabetes
Interventions
BEHAVIORAL
No Results Yet
NCT05814575 | COMPLETED | NA
103 Participants

NEXUS - Next Generation Health Through 2D & 3D Fetal UltraSound; Building Connections to Support Maternal-fetal Health

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2023-06-08
Completion: 2025-11-30
Conditions
Pregnancy Related Substance Use Mental Health Issue
Interventions
BEHAVIORAL
No Results Yet
NCT05814419 | COMPLETED
11 Participants

Familial Hyperlipidemia Family Registry

Study Type: OBSERVATIONAL
Last Updated: 2025-12-19
Start Date: 2023-02-17
Completion: 2025-05-29
Conditions
Familial Hyperlipidemia
NCT05811351 | ACTIVE_NOT_RECRUITING | PHASE2
305 Participants

A Study to Evaluate Intravitreal JNJ-81201887 (AAVCAGsCD59) Compared to Sham Procedure for the Treatment of Geographic Atrophy (GA) Secondary to Age-related Macular Degeneration (AMD)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2023-03-06
Completion: 2026-02-26
Conditions
Geographic Atrophy
Interventions
DRUG OTHER
No Results Yet
NCT05808140 | COMPLETED | PHASE1/PHASE2
40 Participants

Fluorescence Imaging With Indocyanine Green(ICG) in Endoscopic Spinal Surgery

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2023-04-11
Completion: 2025-12-14
Conditions
Disc Herniation
Interventions
DRUG DEVICE
No Results Yet
NCT05802056 | RECRUITING | PHASE1
15 Participants

Aldesleukin With Nivolumab and Standard Chemotherapy for Treatment of Gastric Cancer With Peritoneal Metastasis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2023-11-29
Completion: 2027-04-15
Conditions
Clinical Stage IV Gastric Cancer AJCC v8 Gastric Adenocarcinoma Gastroesophageal Junction Adenocarcinoma Metastatic Gastric Carcinoma Metastatic Malignant Neoplasm in the Peritoneum
Interventions
BIOLOGICAL PROCEDURE DRUG
No Results Yet
NCT05796206 | ACTIVE_NOT_RECRUITING | PHASE2
120 Participants

A Phase 2 Clinical Study of MIL62 in Systemic Lupus Erythematosus

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2023-05-26
Completion: 2026-02-28
Conditions
Systemic Lupus Erythematosus
Interventions
DRUG
No Results Yet
NCT05795049 | ACTIVE_NOT_RECRUITING
2000 Participants

Genetic Carbohydrate Maldigestion as a Model to Study Food Hypersensitivity

Study Type: OBSERVATIONAL
Last Updated: 2025-12-19
Start Date: 2024-07-23
Completion: 2025-09-30
Conditions
Irritable Bowel Syndrome (IBS) Sucrase Isomaltase Deficiency
Interventions
OTHER
No Results Yet
NCT05794906 | ACTIVE_NOT_RECRUITING | PHASE3
981 Participants

A Study to Compare Darolutamide Given With Androgen Deprivation Therapy (ADT) With ADT in Men With Hormone Sensitive Prostate Cancer and Raise of Prostate Specific Antigen (PSA) Levels After Local Therapies

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2023-04-03
Completion: 2027-07-30
Conditions
Biochemically Recurrent Prostate Cancer
Interventions
DRUG OTHER
No Results Yet
NCT05793138 | ENROLLING_BY_INVITATION | NA
120 Participants

Dialysis Geriatric Care Model

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2025-12-01
Completion: 2028-08-31
Conditions
Chronic Kidney Diseases Dialysis Geriatric
Interventions
BEHAVIORAL
No Results Yet
NCT05792930 | RECRUITING | NA
60 Participants

Developing an Integrated Psychotherapy With Cognitive-behavioral Therapy and Biofeedback Therapy for Somatic Symptom Disorder

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2023-07-11
Completion: 2026-06-30
Conditions
Somatic Symptom Disorder
Interventions
BEHAVIORAL
No Results Yet
NCT05781113 | RECRUITING
90 Participants

A Novel Wearable Digital Biomarker for Detecting Changes in Multiple Sclerosis (MS) Condition

Study Type: OBSERVATIONAL
Last Updated: 2025-12-19
Start Date: 2023-07-01
Completion: 2026-09-01
Conditions
Multiple Sclerosis
No Results Yet
NCT05775094 | ACTIVE_NOT_RECRUITING | PHASE1
10 Participants

A Study of Romosozumab in Women With Multiple Myeloma and Osteoporosis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2023-03-07
Completion: 2027-03-31
Conditions
Osteoporosis Multiple Myeloma
Interventions
DRUG
No Results Yet
NCT05767970 | COMPLETED | NA
2315 Participants

Stress Toolbox for Healthcare Providers in Mexico

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2023-04-04
Completion: 2024-03-31
Conditions
Distress, Emotional Burnout, Professional Inflammation Emotion Regulation
Interventions
BEHAVIORAL
No Results Yet
NCT05764057 | RECRUITING | PHASE3
450 Participants

DAPAgliflozine to Attenuate Cardiac RemOdeling afTEr aCuTe myOcardial Infarction

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2023-06-12
Completion: 2026-10-12
Conditions
AMI STEMI NSTEMI Left Ventricular Dysfunction
Interventions
DRUG
No Results Yet
NCT05761899 | RECRUITING | PHASE1/PHASE2
3 Participants

Safety and Efficacy of PMT Therapy of hPAP

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2023-06-26
Completion: 2026-09-01
Conditions
Hereditary Pulmonary Alveolar Proteinosis
Interventions
COMBINATION_PRODUCT
No Results Yet
NCT05758909 | ACTIVE_NOT_RECRUITING
585 Participants

Evaluation of the Viability and Safety of Early Discharge Protocol After TAVI Implantation

Study Type: OBSERVATIONAL
Last Updated: 2025-12-19
Start Date: 2023-04-04
Completion: 2026-12-01
Conditions
Aortic Valve Stenosis Heart Valve Diseases Aortic Valve Disease
Interventions
DEVICE
No Results Yet
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