Stress Toolbox for Healthcare Providers in Mexico

NCT ID: NCT05767970

Last Updated: 2025-12-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

2315 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-04-04

Study Completion Date

2025-09-29

Brief Summary

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The goal of this randomized wait-list clinical trial is to test in patient facing Mexican healthcare providers the efficacy of the Integrated Toolbox for Healthcare Providers (ISTH) on psychological functioning, well-being, occupational performance, and peripheral inflammation.

The main questions this study aims to answer are:

* Does assignment to the ISTH predict reduced psychological distress and increased well-being?
* Does assignment to the ISTH predict improved occupational outcomes and social-emotional competencies?

Participants will be randomly assigned to either the ISTH, a 12-week synchronous and app-based well-being training or to a wait-list control condition and complete assessments 8 times over the nine-month study period.

Researchers will compare the ISTH and the wait-list control group across time to evaluate ISTH impacts.

Detailed Description

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Using the random permuted block method, healthcare providers from up to six Mexican states in three tiers of healthcare facilities (low, middle, and high resource) will be randomly assigned to either the 12-week ISTH intervention or wait-list control.

The ISTH consists of eight, two-hour synchronous sessions (via ZOOM) that are recorded and available to participants on a private Youtube channel for one week. Class learning is reinforced through content provided on a special version of the Healthy Mind Program app designed for this study. Weeks 8-12 of the intervention are app only, with a final two-hour synchronous session at week 12. All study content (i.e., intervention, assessments) are in Spanish.

All participants will be asked to complete a baseline assessment battery, shorter assessments after weeks 1, 3, 5, and 8, and a battery of assessments after week 12 (post-intervention), after week 24 (three-month follow-up), and after week 36 (six-month follow-up).

Researchers will randomly sample from participants opting into the dried blood spot substudy 510 participants (255 per condition) for dried blood spot collection at baseline, after week 12, and after week 24. Researchers will randomly sample from participants opting into the patient satisfaction substudy patient satisfaction reports from 4-10 of their patients at baseline, after week 12 (post-intervention) and after week 24 (three-month follow-up). Researchers will prioritize that selected participants who opted into both substudies are enrolled in the substudies.

Healthcare systems/clinics within: Nuevo León, Coahuila, Oaxaca, Querétaro, Campeche, Jalisco, and Sonora may participate.

Conditions

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Distress, Emotional Burnout, Professional Inflammation Emotion Regulation

Keywords

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Well-being

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Random permuted block parallel assignment
Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Investigators Outcome Assessors
Assessments will be collected online or through professional data collection service (for dried blood spots and patient satisfaction reports) that will be blind to condition assignment. The investigators responsible for data analysis will be blind to condition assignment until after primary analyses are complete.

Study Groups

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Integrated Stress Toolbox for Healthcare Providers (ISTH)

A 12-week synchronous and app-based well-being training that involves weekly 2-hour sessions for weeks 1-8 and at week 12, along with 12-weeks of app-based content delivered through a special version of the Healthy Minds Program app.

Group Type EXPERIMENTAL

Integrated Stress Toolbox for Healthcare Providers (ISTH)

Intervention Type BEHAVIORAL

The ISTH is a 12-week meditation-based well-being training. In weeks 1-8, participants engage in weekly 2-hour class sessions that are recorded and posted on a private Youtube channel for one week. There is a final two-hour session at week 12. In-class learning is augmented and extended through content in a special version of the Healthy Minds Program smartphone app that participants are asked to use on a daily basis throughout the intervention.

Wait-list control

The wait-list control group will continue with business as usual and receive the ISTH after the last data collection point.

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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Integrated Stress Toolbox for Healthcare Providers (ISTH)

The ISTH is a 12-week meditation-based well-being training. In weeks 1-8, participants engage in weekly 2-hour class sessions that are recorded and posted on a private Youtube channel for one week. There is a final two-hour session at week 12. In-class learning is augmented and extended through content in a special version of the Healthy Minds Program smartphone app that participants are asked to use on a daily basis throughout the intervention.

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* ≥ 18 years old
* Employee in a participating healthcare system in a participating Mexican State

Exclusion Criteria

* \<18 years old
* Not in a participant healthcare system in a participating state
* Does not work in a qualifying healthcare provider role
* Does not have regular access to reliable internet and/or a smartphone capable of downloading the Healthy Minds Program app
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Templeton World Charity Foundation, Inc

UNKNOWN

Sponsor Role collaborator

University of Wisconsin, Madison

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Leandro Chernicoff, MS

Role: STUDY_DIRECTOR

AtentaMente

Locations

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Campeche State

All, Campeche, Mexico

Site Status

Coahuila State

All, Coahuila, Mexico

Site Status

Jalisco State

All, Jalisco, Mexico

Site Status

Nuevo Leon State

All, Nuevo León, Mexico

Site Status

Querétaro State

All, Querétaro, Mexico

Site Status

Sonora State

All, Sonora, Mexico

Site Status

Oaxaca State

Oaxaca City, , Mexico

Site Status

Countries

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Mexico

References

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Mehling WE, Price C, Daubenmier JJ, Acree M, Bartmess E, Stewart A. The Multidimensional Assessment of Interoceptive Awareness (MAIA). PLoS One. 2012;7(11):e48230. doi: 10.1371/journal.pone.0048230. Epub 2012 Nov 1.

Reference Type BACKGROUND
PMID: 23133619 (View on PubMed)

Gilbert, P., Catarino, F., Duarte, C., Matos, M., Kolts, R., Stubbs, J., ... & Basran, J. (2017). The development of compassionate engagement and action scales for self and others. Journal of Compassionate Health Care, 4, 1-24.

Reference Type BACKGROUND

Steger, M. F., Frazier, P., Oishi, S., & Kaler, M. (2006). The meaning in life questionnaire: assessing the presence of and search for meaning in life. Journal of counseling psychology, 53(1), 80.

Reference Type BACKGROUND

Baer RA, Smith GT, Lykins E, Button D, Krietemeyer J, Sauer S, Walsh E, Duggan D, Williams JM. Construct validity of the five facet mindfulness questionnaire in meditating and nonmeditating samples. Assessment. 2008 Sep;15(3):329-42. doi: 10.1177/1073191107313003. Epub 2008 Feb 29.

Reference Type BACKGROUND
PMID: 18310597 (View on PubMed)

Davis, M. H. (1980). Interpersonal reactivity index.

Reference Type BACKGROUND

Garnefski, N., & Kraaij, V. (2007). The cognitive emotion regulation questionnaire. European journal of psychological assessment, 23(3), 141-149.

Reference Type BACKGROUND

Pilkonis PA, Choi SW, Reise SP, Stover AM, Riley WT, Cella D; PROMIS Cooperative Group. Item banks for measuring emotional distress from the Patient-Reported Outcomes Measurement Information System (PROMIS(R)): depression, anxiety, and anger. Assessment. 2011 Sep;18(3):263-83. doi: 10.1177/1073191111411667. Epub 2011 Jun 21.

Reference Type BACKGROUND
PMID: 21697139 (View on PubMed)

Cohen S, Kamarck T, Mermelstein R. A global measure of perceived stress. J Health Soc Behav. 1983 Dec;24(4):385-96. No abstract available.

Reference Type BACKGROUND
PMID: 6668417 (View on PubMed)

Bech, P. (2004). Measuring the dimension of psychological general well-being by the WHO-5. Quality of Life Newsletter, 15-16.

Reference Type BACKGROUND

Maslach, C., Jackson, S. E., & Leiter, M. P. (1996). Maslach burnout inventory manual. Mountain View, CA: CPP. Inc., and Davies-Black.

Reference Type BACKGROUND

Mccullough ME, Emmons RA, Tsang JA. The grateful disposition: a conceptual and empirical topography. J Pers Soc Psychol. 2002 Jan;82(1):112-27. doi: 10.1037//0022-3514.82.1.112.

Reference Type BACKGROUND
PMID: 11811629 (View on PubMed)

Hirshberg MJ, Davidson RJ, Velarde Arrisueno LB, Olvera Puentes JM, Bardalez XM, Gonzalez BS, Goldberg SB, Chernicoff LI; HCP-Well Study Group. Digital Well-Being Training With Health Care Professionals: A Randomized Clinical Trial. JAMA Intern Med. 2025 Aug 18;185(10):1248-56. doi: 10.1001/jamainternmed.2025.3888. Online ahead of print.

Reference Type DERIVED
PMID: 40824577 (View on PubMed)

Other Identifiers

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Center for Healthy Minds

Identifier Type: OTHER

Identifier Source: secondary_id

L&S/PSYCHOLOGY/PSYCHOLOGY

Identifier Type: OTHER

Identifier Source: secondary_id

2023-0090

Identifier Type: -

Identifier Source: org_study_id