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Clinical Trials

Showing trials with last updates posted in 2025.

NCT05863754 | RECRUITING | NA
13 Participants

Grasp-Release Assessment of a Networked Neuroprosthesis Device

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2022-01-23
Completion: 2027-12-01
Conditions
Spinal Cord Injury at C5-C7 Level Spinal Cord Injuries Spinal Cord Injury Cervical
Interventions
DEVICE
No Results Yet
NCT05852353 | COMPLETED | NA
204 Participants

Impact, Feasibility, and Acceptability of Bladder Basics

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2023-08-22
Completion: 2024-11-10
Conditions
Health Knowledge, Attitudes, Practice
Interventions
OTHER
Results Available
NCT05838573 | RECRUITING | PHASE3
120 Participants

Metformin Treatment on Cognitive Impairment of Schizophrenia

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2023-05-08
Completion: 2026-12-12
Conditions
Schizophrenia
Interventions
DRUG OTHER
No Results Yet
NCT05826119 | COMPLETED | NA
60 Participants

Intravenous Administration of Magnesium Sulfate in Laparoscopic Hysterectomy Cases

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2024-01-20
Completion: 2024-03-30
Conditions
Laparoscopic Hysterectomy Magnesium Sulfate General Anesthesia
Interventions
DRUG
No Results Yet
NCT05823142 | RECRUITING | NA
300 Participants

Health Behavior Intervention for Adults With Type 1 Diabetes

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2023-12-20
Completion: 2028-07-31
Conditions
Type1diabetes
Interventions
BEHAVIORAL
No Results Yet
NCT05814575 | COMPLETED | NA
103 Participants

NEXUS - Next Generation Health Through 2D & 3D Fetal UltraSound; Building Connections to Support Maternal-fetal Health

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2023-06-08
Completion: 2025-11-30
Conditions
Pregnancy Related Substance Use Mental Health Issue
Interventions
BEHAVIORAL
No Results Yet
NCT05814419 | COMPLETED
11 Participants

Familial Hyperlipidemia Family Registry

Study Type: OBSERVATIONAL
Last Updated: 2025-12-19
Start Date: 2023-02-17
Completion: 2025-05-29
Conditions
Familial Hyperlipidemia
Results Available
NCT05811351 | ACTIVE_NOT_RECRUITING | PHASE2
305 Participants

A Study to Evaluate Intravitreal JNJ-81201887 (AAVCAGsCD59) Compared to Sham Procedure for the Treatment of Geographic Atrophy (GA) Secondary to Age-related Macular Degeneration (AMD)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2023-03-06
Completion: 2026-02-26
Conditions
Geographic Atrophy
Interventions
DRUG OTHER
No Results Yet
NCT05808140 | COMPLETED | PHASE1/PHASE2
40 Participants

Fluorescence Imaging With Indocyanine Green(ICG) in Endoscopic Spinal Surgery

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2023-04-11
Completion: 2025-12-14
Conditions
Disc Herniation
Interventions
DRUG DEVICE
No Results Yet
NCT05802056 | RECRUITING | PHASE1
15 Participants

Aldesleukin With Nivolumab and Standard Chemotherapy for Treatment of Gastric Cancer With Peritoneal Metastasis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2023-11-29
Completion: 2027-04-15
Conditions
Clinical Stage IV Gastric Cancer AJCC v8 Gastric Adenocarcinoma Gastroesophageal Junction Adenocarcinoma Metastatic Gastric Carcinoma Metastatic Malignant Neoplasm in the Peritoneum
Interventions
BIOLOGICAL PROCEDURE DRUG
No Results Yet
NCT05796206 | ACTIVE_NOT_RECRUITING | PHASE2
120 Participants

A Phase 2 Clinical Study of MIL62 in Systemic Lupus Erythematosus

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2023-05-26
Completion: 2026-02-28
Conditions
Systemic Lupus Erythematosus
Interventions
DRUG
No Results Yet
NCT05795049 | ACTIVE_NOT_RECRUITING
2000 Participants

Genetic Carbohydrate Maldigestion as a Model to Study Food Hypersensitivity

Study Type: OBSERVATIONAL
Last Updated: 2025-12-19
Start Date: 2024-07-23
Completion: 2025-09-30
Conditions
Irritable Bowel Syndrome (IBS) Sucrase Isomaltase Deficiency
Interventions
OTHER
No Results Yet
NCT05794906 | ACTIVE_NOT_RECRUITING | PHASE3
981 Participants

A Study to Compare Darolutamide Given With Androgen Deprivation Therapy (ADT) With ADT in Men With Hormone Sensitive Prostate Cancer and Raise of Prostate Specific Antigen (PSA) Levels After Local Therapies

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2023-04-03
Completion: 2027-07-30
Conditions
Biochemically Recurrent Prostate Cancer
Interventions
DRUG OTHER
No Results Yet
NCT05793138 | ENROLLING_BY_INVITATION | NA
120 Participants

Dialysis Geriatric Care Model

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2025-12-01
Completion: 2028-08-31
Conditions
Chronic Kidney Diseases Dialysis Geriatric
Interventions
BEHAVIORAL
No Results Yet
NCT05792930 | RECRUITING | NA
60 Participants

Developing an Integrated Psychotherapy With Cognitive-behavioral Therapy and Biofeedback Therapy for Somatic Symptom Disorder

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2023-07-11
Completion: 2026-06-30
Conditions
Somatic Symptom Disorder
Interventions
BEHAVIORAL
No Results Yet
NCT05781113 | RECRUITING
90 Participants

A Novel Wearable Digital Biomarker for Detecting Changes in Multiple Sclerosis (MS) Condition

Study Type: OBSERVATIONAL
Last Updated: 2025-12-19
Start Date: 2023-07-01
Completion: 2026-09-01
Conditions
Multiple Sclerosis
No Results Yet
NCT05775094 | ACTIVE_NOT_RECRUITING | PHASE1
10 Participants

A Study of Romosozumab in Women With Multiple Myeloma and Osteoporosis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2023-03-07
Completion: 2027-03-31
Conditions
Osteoporosis Multiple Myeloma
Interventions
DRUG
No Results Yet
NCT05767970 | COMPLETED | NA
2315 Participants

Stress Toolbox for Healthcare Providers in Mexico

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2023-04-04
Completion: 2024-03-31
Conditions
Distress, Emotional Burnout, Professional Inflammation Emotion Regulation
Interventions
BEHAVIORAL
No Results Yet
NCT05764057 | RECRUITING | PHASE3
450 Participants

DAPAgliflozine to Attenuate Cardiac RemOdeling afTEr aCuTe myOcardial Infarction

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2023-06-12
Completion: 2026-10-12
Conditions
AMI STEMI NSTEMI Left Ventricular Dysfunction
Interventions
DRUG
No Results Yet
NCT05761899 | RECRUITING | PHASE1/PHASE2
3 Participants

Safety and Efficacy of PMT Therapy of hPAP

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2023-06-26
Completion: 2026-09-01
Conditions
Hereditary Pulmonary Alveolar Proteinosis
Interventions
COMBINATION_PRODUCT
No Results Yet
NCT05758909 | ACTIVE_NOT_RECRUITING
585 Participants

Evaluation of the Viability and Safety of Early Discharge Protocol After TAVI Implantation

Study Type: OBSERVATIONAL
Last Updated: 2025-12-19
Start Date: 2023-04-04
Completion: 2026-12-01
Conditions
Aortic Valve Stenosis Heart Valve Diseases Aortic Valve Disease
Interventions
DEVICE
No Results Yet
NCT05757869 | ACTIVE_NOT_RECRUITING | PHASE3
20283 Participants

A Study of Milvexian Versus Apixaban in Participants With Atrial Fibrillation

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2023-04-11
Completion: 2026-10-31
Conditions
Atrial Fibrillation
Interventions
DRUG
No Results Yet
NCT05747625 | RECRUITING | PHASE1
60 Participants

(89Zr Panitumumab) With PET/CT for Diagnosing Metastases in Patients With Head and Neck Squamous Cell Carcinoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2023-05-09
Completion: 2027-02-28
Conditions
Head and Neck Squamous Cell Carcinoma Metastatic Head and Neck Squamous Cell Carcinoma Stage IV Cutaneous Squamous Cell Carcinoma of the Head and Neck
Interventions
BIOLOGICAL DRUG PROCEDURE OTHER
No Results Yet
NCT05745493 | COMPLETED | NA
29 Participants

Study 1: Social Engage Coaching R61 Phase

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2023-06-13
Completion: 2025-09-30
Conditions
Social Isolation Loneliness Suicide Ideation Quality of Life
Interventions
BEHAVIORAL
No Results Yet
NCT05741580 | COMPLETED
70 Participants

Peri-urethral Bulk Agent Injection of Bulkamid®

Study Type: OBSERVATIONAL
Last Updated: 2025-12-19
Start Date: 2022-10-01
Completion: 2022-11-30
Conditions
Urinary Incontinence
Interventions
PROCEDURE
No Results Yet
NCT05727384 | ACTIVE_NOT_RECRUITING | PHASE2
29 Participants

Improving Physical Function in Older Adults Using an Anti-inflammation Drug: The RIGHT Study

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2023-08-01
Completion: 2026-02-28
Conditions
Inflammation Frailty
Interventions
DRUG
No Results Yet
NCT05716100 | RECRUITING | PHASE3
360 Participants

A Randomized Study of XEN1101 Versus Placebo in Focal-Onset Seizures (X-TOLE3)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2023-05-09
Completion: 2026-10-31
Conditions
Focal Onset Seizures
Interventions
DRUG
No Results Yet
NCT05714202 | ACTIVE_NOT_RECRUITING | PHASE3
1135 Participants

A Study of TAR-200 in Combination With Cetrelimab or TAR-200 Alone Versus Intravesical Bacillus Calmette-Guérin (BCG) in Participants With BCG-naïve High-risk Non-muscle Invasive Bladder Cancer (HR-NMIBC)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2023-03-23
Completion: 2029-09-18
Conditions
Bladder Cancer
Interventions
DRUG BIOLOGICAL
No Results Yet
NCT05714085 | RECRUITING | PHASE2/PHASE3
342 Participants

Efficacy, Safety, and Pharmacokinetics of Vericiguat in Pediatric Participants With Heart Failure Due to Left Ventricular Systolic Dysfunction (MK-1242-036)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2023-05-31
Completion: 2032-04-15
Conditions
Heart Failure Left Ventricular Systolic Dysfunction
Interventions
DRUG
No Results Yet
NCT05702034 | RECRUITING | PHASE3
15000 Participants

A Study of Milvexian in Participants After an Acute Ischemic Stroke or High-Risk Transient Ischemic Attack- LIBREXIA-STROKE

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2023-02-15
Completion: 2026-11-11
Conditions
Ischemic Stroke; Ischemic Attack, Transient
Interventions
DRUG
No Results Yet
NCT05696392 | TERMINATED | PHASE4
47 Participants

The Purpose of This Study is to Evaluate the Effects of Ruxolitinib Cream on Adults With Atopic Dermatitis Experiencing Sleep Disturbance.

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2023-03-16
Completion: 2025-01-22
Conditions
Atopic Dermatitis
Interventions
DRUG
Results Available
NCT05675449 | RECRUITING | PHASE1
90 Participants

A Clinical Trial of Four Medicines (Elranatamab Plus Carfilzomib and Dexamethasone or Maplirpacept) in People With Relapsed Refractory Multiple Myeloma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2022-12-14
Completion: 2026-04-22
Conditions
Multiple Myeloma
Interventions
DRUG
No Results Yet
NCT05667142 | RECRUITING | PHASE3
160 Participants

A Study to Evaluate XEN1101 as Adjunctive Therapy in Primary Generalized Tonic-Clonic Seizures

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2023-02-14
Completion: 2027-04-30
Conditions
Primary Generalized Tonic-Clonic Seizures
Interventions
DRUG
No Results Yet
NCT05663203 | RECRUITING | NA
56 Participants

A Web-Based Dyadic Intervention for Colorectal Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2023-05-01
Completion: 2026-10-01
Conditions
Colorectal Carcinoma
Interventions
OTHER
No Results Yet
NCT05661916 | COMPLETED | PHASE1
96 Participants

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ALN-TTRSC04 in Healthy Subjects

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2023-01-16
Completion: 2025-09-30
Conditions
Transthyretin-Mediated Amyloidosis
Interventions
DRUG
No Results Yet
NCT05637112 | ACTIVE_NOT_RECRUITING
551 Participants

A Treatment Effectiveness Study Among SLE Patients Receiving Anifrolumab in Routine Clinical Practice

Study Type: OBSERVATIONAL
Last Updated: 2025-12-19
Start Date: 2023-02-27
Completion: 2030-12-30
Conditions
Systemic Lupus Erythematosus
Interventions
OTHER
No Results Yet
NCT05629585 | ACTIVE_NOT_RECRUITING | PHASE3
1174 Participants

A Study of Dato-DXd With or Without Durvalumab Versus Investigator's Choice of Therapy in Patients With Stage I-III Triple-negative Breast Cancer Without Pathological Complete Response Following Neoadjuvant Therapy (TROPION-Breast03)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2022-11-28
Completion: 2027-09-20
Conditions
Breast Cancer
Interventions
DRUG
No Results Yet
NCT05628948 | RECRUITING
500 Participants

Vascular Lab Resource (VLR) Biorepository

Study Type: OBSERVATIONAL
Last Updated: 2025-12-19
Start Date: 2019-11-14
Completion: 2030-12-31
Conditions
Cardiovascular Diseases Metabolic Disease Peripheral Artery Disease Carotid Disease Aneurysmal Disease Venous Disease Thrombosis Lymphedema Lipedema Non-Atherosclerotic Chronic Arterial Occlusive Disease Vasculitis Fibromuscular Dysplasia Arterial Dissection May-Thurner Syndrome Thoracic Outlet Syndrome Vasospasm
No Results Yet
NCT05616793 | RECRUITING | PHASE1/PHASE2
22 Participants

Safety and Tolerability Subretinal OPGx-001 for LCA5-Associated Inherited Retinal Degeneration (LCA5-IRD) and Non-interventional Arm With Untreated Patients

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2023-06-15
Completion: 2028-06-15
Conditions
LCA5
Interventions
BIOLOGICAL
No Results Yet
NCT05616273 | COMPLETED
62 Participants

Stimulated Glucagon as a Biomarker of Hypoglycemic Risk in Type 1 Diabetes

Study Type: OBSERVATIONAL
Last Updated: 2025-12-19
Start Date: 2023-05-03
Completion: 2025-01-28
Conditions
Type 1 Diabetes Hypoglycemia
Interventions
OTHER
No Results Yet
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