Clinical Trials
Showing trials with last updates posted in 2025.
64
Participants
Study of BGB-11417 in Adult Participants With Mature B-cell Malignancies
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2021-07-05
Completion:
2026-04-30
Conditions
Mature B-cell Malignancies
Interventions
DRUG
No Results Yet
150
Participants
ELEVATE, a Registry of Patients With Acute Hepatic Porphyria (AHP)
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-19
Start Date:
2021-04-26
Completion:
2027-04-01
Conditions
Acute Hepatic Porphyria
No Results Yet
178
Participants
Combination of Baricitinib and Anti-TNF in Rheumatoid Arthritis
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2021-07-15
Completion:
2027-03-31
Conditions
Rheumatoid Arthritis
Interventions
DRUG
No Results Yet
78
Participants
A Clinical Observational Study of SARS-CoV-2 Specific CD8 T-Cell Responses to COVID-19 Vaccines in Humans
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-19
Start Date:
2021-04-20
Completion:
2026-12-31
Conditions
COVID-19
No Results Yet
22
Participants
Efficacy of FES Cycling After a Severe Form of COVID-19
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2021-06-02
Completion:
2024-10-02
Conditions
Covid19
Ventilators, Mechanical
Respiratory Distress Syndrome
Interventions
BEHAVIORAL
No Results Yet
6
Participants
Non-Contrast Perfusion Using Arterial Spin Labeled MR Imaging for Assessment of Therapy Response in Metastatic Renal Cell Carcinoma
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2021-03-24
Completion:
2023-04-04
Conditions
Renal Cell Carcinoma
Interventions
OTHER
160
Participants
Spectroscopy in Ovarian Cancer
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-19
Start Date:
2021-06-28
Completion:
2023-10-01
Conditions
Ovarian Cancer
Ovarian Neoplasms
Ovary Cyst
Ovary Disease
No Results Yet
50
Participants
Comparing the Addition of an Anti-Cancer Drug, Pomalidomide, to the Usual Chemotherapy Treatment (Daunorubicin and Cytarabine Liposome) in Newly Diagnosed Acute Myeloid Leukemia With Myelodysplastic Syndrome-Related Changes
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2022-08-24
Completion:
2024-11-21
Conditions
Acute Myeloid Leukemia
Acute Myeloid Leukemia Post Cytotoxic Therapy
Acute Myeloid Leukemia With Multilineage Dysplasia
Chronic Myelomonocytic Leukemia
Myelodysplastic Syndrome
Myeloproliferative Neoplasm
Interventions
PROCEDURE
DRUG
360
Participants
Coronary CT Angio Evaluating Graft Patency in ACS Patients Treated With DAPT or Single ASA After CABG (CoCAP)
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-19
Start Date:
2021-05-17
Completion:
2026-02-01
Conditions
Acute Coronary Syndrome
Coronary Bypass Stenosis
No Results Yet
225
Participants
Characterizing Inflammatory Profiles and Suicidal Behavior in Adolescents
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-19
Start Date:
2021-04-28
Completion:
2025-06-15
Conditions
Suicide and Depression
Interventions
OTHER
No Results Yet
0
Participants
Chitogel CSK-4 Gel as Packing in Tympanoplasty Surgery
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-19
Start Date:
2021-01-14
Completion:
2021-11-03
Conditions
Tympanoplasty Surgery
Interventions
BIOLOGICAL
No Results Yet
90
Participants
PrEP at a Syringe Services Program
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2022-02-01
Completion:
2024-11-11
Conditions
Hiv
Substance Use Disorders
Interventions
DRUG
BEHAVIORAL
380
Participants
A Study to Assess Change in Disease Activity and Adverse Events (AEs) With Cariprazine in the Treatment of Depressive Episodes in Pediatric Participants Participants (10 to 17 Years of Age) With Bipolar I Disorder.
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2021-04-28
Completion:
2027-03-31
Conditions
Depression
Bipolar I Disorder
Interventions
DRUG
No Results Yet
220
Participants
Neutrophil Phenotypic Profiling and Surgical Site Infections in Surgical Patients
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-19
Start Date:
2023-04-01
Completion:
2026-12-01
Conditions
Surgical Site Infection
Interventions
OTHER
No Results Yet
20
Participants
Impact of Intestinal Microbiota on Uremic Toxins Productions
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2021-06-04
Completion:
2021-07-13
Conditions
CKD
Uremia
Interventions
OTHER
No Results Yet
98
Participants
Asymmetric Lack of Knee Flexion as a Symptom of DLM in Children
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-19
Start Date:
2020-09-01
Completion:
2020-11-01
Conditions
Highlights a New Clinical Sign Which Point Out a Meniscus Posterior Luxation Because of a MCA-type DLM
Interventions
DIAGNOSTIC_TEST
No Results Yet
181
Participants
Telehealth Based Intervention to Improve Functional Capacity in Survivors of Childhood Cancer With Significantly Limited Exercise Tolerance
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2021-02-08
Completion:
2025-09-15
Conditions
Childhood Cancer
Mobility Limitation
Interventions
OTHER
No Results Yet
18
Participants
A Pilot Study of Ketogenic Diet and Metformin in Glioblastoma: Feasibility and Metabolic Imaging
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2016-08-31
Completion:
2026-06-30
Conditions
Glioblastoma
Interventions
OTHER
DRUG
No Results Yet
153
Participants
Digitally Enhanced Smoking Cessation for High Risk Smokers
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2021-02-01
Completion:
2023-02-01
Conditions
Smoking
Smoking Cessation
Lung Cancer Screening
Smoking, Tobacco
Smoking Behaviors
Interventions
OTHER
No Results Yet
32
Participants
Pemigatinib After Chemotherapy for the Treatment of Newly Diagnosed Acute Myeloid Leukemia
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2021-01-14
Completion:
2026-12-31
Conditions
Acute Myeloid Leukemia
Interventions
PROCEDURE
DRUG
No Results Yet
100
Participants
Safety And Efficacy Of TKI Cessation For CML Patients With Stable Molecular Response In A Real World Population
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2020-12-22
Completion:
2028-11-15
Conditions
Chronic Myeloid Leukemia
Chronic Myeloid Leukemia, BCR/ABL-Positive, in Remission
Chronic Myeloid Leukemia in Remission
Interventions
OTHER
DRUG
No Results Yet
50
Participants
Clinical Relevance of Intracellular Staphylococci in BOne and Joint Infections
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-19
Start Date:
2020-12-01
Completion:
2021-09-20
Conditions
Staphylococcus
Bone and Joint Infection
Interventions
OTHER
No Results Yet
440
Participants
Coping Together: Couple-based Interventions for Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2020-10-20
Completion:
2025-12-30
Conditions
Advanced Cancer
Interventions
BEHAVIORAL
No Results Yet
20
Participants
Feasibility Study of Cortical Recording Depolarizations in Brain-injured Patients, and Their Use as Biomarkers of New Lesions.
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2021-01-01
Completion:
2023-04-07
Conditions
Brain Lesion
Head Trauma
Subarachnoid Hemorrhage
Interventions
DEVICE
No Results Yet
163
Participants
Methotrexate in Erosive Inflammatory Hand Osteoarthritis
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2021-08-12
Completion:
2026-12-31
Conditions
Hand Osteoarthritis
Erosive Osteoarthritis
Interventions
DRUG
No Results Yet
217
Participants
Basket Study of Tucatinib and Trastuzumab in Solid Tumors With HER2 Alterations
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2021-01-11
Completion:
2023-11-01
Conditions
Uterine Neoplasms
Uterine Cervical Neoplasms
Biliary Tract Neoplasms
Urologic Neoplasms
Carcinoma, Non-Small-Cell Lung
HER2 Mutations Breast Neoplasms
Interventions
DRUG
500
Participants
Alterations of the Microbiome During Critical Illness With Short and Long Term Clinical Outcomes
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-19
Start Date:
2020-09-15
Completion:
2026-06-01
Conditions
Critical Illness
Microbiome
No Results Yet
200
Participants
A Platform Study of Novel Agents in Combination With Radiotherapy in NSCLC
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2021-03-17
Completion:
2026-03-31
Conditions
Non Small Cell Lung Cancer
Interventions
RADIATION
DRUG
No Results Yet
243
Participants
Vagus Nerve Stimulation for Moderate to Severe Rheumatoid Arthritis
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2021-01-11
Completion:
2024-05-16
Conditions
Rheumatoid Arthritis
Interventions
PROCEDURE
DRUG
DEVICE
113
Participants
Peer Approaches to Substances in Early Psychosis Programs: A Pilot Study of a Peer-Led Intervention
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2023-08-22
Completion:
2025-07-25
Conditions
Substance Use
Psychotic Disorders
Interventions
BEHAVIORAL
No Results Yet
320
Participants
A Trial to Evaluate Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of TST001 in Advanced or Metastatic Solid Tumors
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2020-08-13
Completion:
2026-06-25
Conditions
Advanced Cancer
Interventions
DRUG
No Results Yet
474
Participants
Randomized Controlled Trial of urinE chemiStry Guided aCute heArt faiLure treATmEnt (ESCALATE)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2022-05-01
Completion:
2026-09-30
Conditions
Heart Failure
Acute Heart Failure
Interventions
DRUG
No Results Yet
292
Participants
A Study to Test if Fremanezumab is Effective in Preventing Chronic Migraine in Participants 6 to 17 Years of Age
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2020-09-24
Completion:
2024-11-29
Conditions
Migraine
Interventions
DRUG
151
Participants
Phase 3 Study of Pyrotinib Versus Docetaxel in Patients With Advanced Non-squamous NSCLC Harboring a HER2 Exon 20 Mutation Who Failed Platinum Based Chemotherapy
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2020-09-11
Completion:
2023-06-02
Conditions
Non-squamous NSCLC
HER2 Exon 20 Mutation
Interventions
DRUG
No Results Yet
60
Participants
fMRI and IVCM Cornea Microscopy of CXL in Keratoconus
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-19
Start Date:
2021-10-04
Completion:
2027-08-31
Conditions
Pain, Postoperative
Pain, Chronic
Pain, Acute
Surgical Injury
Surgical Wound
Cornea Injury
Cornea
Keratoconus
No Results Yet
15
Participants
Renal Metabolism of Glycolate to Oxalate
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2020-03-12
Completion:
2026-09-01
Conditions
Healthy
Interventions
DIETARY_SUPPLEMENT
OTHER
No Results Yet
1000
Participants
Screening for NAFLD-related Advanced Fibrosis in High Risk Population in Diabetology.
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2020-10-28
Completion:
2023-10-28
Conditions
Non-Alcoholic Fatty Liver Disease
Interventions
DIAGNOSTIC_TEST
No Results Yet
20
Participants
Combining Pembrolizumab and Metformin in Metastatic Head and Neck Cancer Patients
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2020-08-31
Completion:
2025-12-31
Conditions
Head and Neck Squamous Cell Carcinoma
Interventions
DRUG
No Results Yet
0
Participants
Intermediate IND Severe Illness COVID-19 CP
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2020-04-07
Completion:
2021-04-07
Conditions
Severe Acute Respiratory Syndrome
COVID
Interventions
DRUG
No Results Yet
255
Participants
Improving Spine Surgical Care With Real-Time Objective Patient Tracking Using the Apple Watch
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2020-09-01
Completion:
2024-11-30
Conditions
Spine Disease
Spine Degeneration
Spinal Stenosis
Surgery
Spine Fusion
Interventions
DEVICE
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