PrEP at a Syringe Services Program

NCT ID: NCT04782180

Last Updated: 2025-12-19

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE4

Total Enrollment

90 participants

Study Classification

INTERVENTIONAL

Study Start Date

2022-02-01

Study Completion Date

2024-11-11

Brief Summary

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The purpose of this study is to see if providing participants with pre-exposure prophylaxis (PrEP) medicine right away at the IDEA Exchange will help participants remain in HIV negative.

Detailed Description

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Conditions

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Hiv Substance Use Disorders

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

PREVENTION

Blinding Strategy

NONE

Study Groups

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Rapid PrEP group

Participants will receive PrEP i.e. Descovy for 12 months at the syringe services program.

Group Type EXPERIMENTAL

Descovy 200Mg 25Mg Tablet

Intervention Type DRUG

daily Descovy tab by mouth

PrEP

Intervention Type BEHAVIORAL

PrEP will be provided in a community setting by community-based harm reduction program.

Interventions

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Descovy 200Mg 25Mg Tablet

daily Descovy tab by mouth

Intervention Type DRUG

PrEP

PrEP will be provided in a community setting by community-based harm reduction program.

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

1. over the age of 18
2. speak either English or Spanish
3. ability to provide informed consent
4. currently enrolled in the syringe services program
5. have a negative HIV rapid test result
6. estimated creatinine clearance \> 30 ml/minute

Exclusion Criteria

1. do not meet the above criteria of inclusion
2. decline to participate
3. test positive for HIV via rapid test
4. are pregnant or plan on becoming pregnant
5. have symptoms acute HIV.
6. Any other comorbidities that at the discretion of the investigator would prevent the participant from participating in the study.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Gilead Sciences

INDUSTRY

Sponsor Role collaborator

University of Miami

OTHER

Sponsor Role lead

Responsible Party

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Hansel Tookes

Professor of Medicine

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Hansel Tookes

Role: PRINCIPAL_INVESTIGATOR

University of Miami

Locations

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University of Miami

Miami, Florida, United States

Site Status

Countries

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United States

Provided Documents

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Document Type: Study Protocol and Statistical Analysis Plan

View Document

Other Identifiers

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20210017

Identifier Type: -

Identifier Source: org_study_id