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Clinical Trials

Showing trials with last updates posted in 2025.

NCT07170150 | RECRUITING | PHASE3
800 Participants

A Clinical Trial of Trontinemab in Participants With Early Symptomatic Alzheimer's Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2025-11-12
Completion: 2028-06-07
Conditions
Alzheimers Disease
Interventions
DRUG OTHER
No Results Yet
NCT07169734 | RECRUITING | PHASE1/PHASE2
180 Participants

A Study to Investigate ALE.P03 as Monotherapy in Adult Patients With Selected Advanced or Metastatic CLDN1+ Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2025-08-26
Completion: 2029-04-05
Conditions
Cervical Squamous Cell Carcinoma Squamous Non-small-cell Lung Cancer Colorectal Cancer Intrahepatic Cholangiocarcinoma Urothelial Carcinoma
Interventions
DRUG
No Results Yet
NCT07169643 | RECRUITING | PHASE3
140 Participants

Darbepoetin in Patients Candidates for Liver Transplant. (EPO-LT Trial)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2025-11-25
Completion: 2026-12-31
Conditions
Liver Transplant; Complications
Interventions
DRUG
No Results Yet
NCT07169110 | NOT_YET_RECRUITING
35 Participants

Study of the Interprofessional Reproducibility of a Clinical Observation Scale for the Development of Very Premature Infants

Study Type: OBSERVATIONAL
Last Updated: 2025-12-18
Start Date: 2025-12-22
Completion: 2026-12-30
Conditions
Prematurity
Interventions
OTHER
No Results Yet
NCT07169071 | COMPLETED | NA
30 Participants

Effects of Expiratory Muscle Training in Children With Asthma: A Randomised Controlled Trial

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2024-06-01
Completion: 2025-07-31
Conditions
Asthma Childhood Respiratory Muscle Training
Interventions
OTHER
No Results Yet
NCT07167160 | RECRUITING | PHASE2
59 Participants

Chemo-immunotherapy for Cervical Cancer Stage IIICp Trial

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2025-03-10
Completion: 2026-12-31
Conditions
Cervical Cancer Immunochemotherapy
Interventions
DRUG
No Results Yet
NCT07165925 | RECRUITING | NA
174 Participants

Musical Training to Enhance Resilience of Underprivileged School-aged Children

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2025-09-08
Completion: 2027-09-30
Conditions
Resilience Depressive Symptom Anxiety
Interventions
BEHAVIORAL
No Results Yet
NCT07165769 | RECRUITING | PHASE2
47 Participants

Zanubrutinib, Obinutuzumab, and Lenalidomide (ZGR) in the Treatment of Newly Diagnosed Splenic B-cell Lymphoma With Prominent Nucleoli (SBLPN): A Prospective, Open-label, Single-arm Clinical Trial

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2025-09-04
Completion: 2028-12-31
Conditions
Splenic B-cell Lymphoma/Leukaemia With Prominent Nucleoli，SBLPN
Interventions
DRUG
No Results Yet
NCT07165015 | RECRUITING | PHASE1
32 Participants

A Study of Pharmacokinetics and Safety of LY3537031 in Participants With Normal Renal Function and Participants With Renal Impairment

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2025-09-18
Completion: 2026-03-31
Conditions
Renal Impairment Healthy Renal Insufficiency End Stage Renal Disease (ESRD)
Interventions
DRUG
No Results Yet
NCT07164404 | ACTIVE_NOT_RECRUITING | NA
220 Participants

Nicotine Replacement Therapy Prescribing and Lung Cancer Screening in Hospitalized Patients

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2025-11-17
Completion: 2026-04-30
Conditions
Tobacco Use Disorder
Interventions
OTHER
No Results Yet
NCT07163767 | ACTIVE_NOT_RECRUITING
150000 Participants

Acute Myocardial Infarction Prediction Using Artificial Intelligence Applied to Electrocardiogram Images

Study Type: OBSERVATIONAL
Last Updated: 2025-12-18
Start Date: 2025-08-01
Completion: 2028-12-31
Conditions
Acute Myocardial Infarction (AMI) Electrocardiography Artifical Intelligence
Interventions
OTHER
No Results Yet
NCT07157800 | RECRUITING | NA
52 Participants

Effectiveness of Exercises Given Along With Ergonomics Training in Construction Workers

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2025-09-09
Completion: 2025-12-08
Conditions
Work-related Illness
Interventions
OTHER
No Results Yet
NCT07153055 | NOT_YET_RECRUITING | PHASE1/PHASE2
16 Participants

Lurbinectedin With Osimertinib in Transformed Small Cell Lung Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2026-05-31
Completion: 2029-04-30
Conditions
Small Cell Lung Cancer ( SCLC ) Transformed Small Cell Lung Cancer
Interventions
DRUG
No Results Yet
NCT07146048 | NOT_YET_RECRUITING | PHASE3
922 Participants

A Non-Inferiority Trial of Stopping Penicillin in Early Rheumatic Heart Disease: GOAL-Stop

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2026-02-28
Completion: 2029-02-20
Conditions
Rheumatic Heart Disease
Interventions
DRUG
No Results Yet
NCT07145177 | NOT_YET_RECRUITING | PHASE1
30 Participants

177Lu-PSMA-617 With Liver Directed Therapy in Metastatic Castration Resistant Prostate Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2026-01-31
Completion: 2028-10-31
Conditions
Metastatic Prostate Cancer Prostate Cancer
Interventions
DRUG PROCEDURE OTHER
No Results Yet
NCT07137689 | RECRUITING | PHASE1
32 Participants

A Study of LY3537982 in Participants With Kidney Problems Compared With Participants With Normal Kidney Function

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2025-08-18
Completion: 2026-03-31
Conditions
Renal Insufficiency
Interventions
DRUG
No Results Yet
NCT07136597 | NOT_YET_RECRUITING | NA
60 Participants

Narrative Medicine Effects on Burnout and Stress

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2026-03-31
Completion: 2026-06-30
Conditions
Healthcare Professionals
Interventions
BEHAVIORAL
No Results Yet
NCT07134556 | NOT_YET_RECRUITING | PHASE2
25 Participants

Phase II Trial Evaluating the Safety and Efficacy of the Combination of Zimberelimab, Domvanalimab and Sacituzumab Govitecan as 1L Therapy for PD-L1 Positive Advanced TNBC

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2025-12-08
Completion: 2028-05-28
Conditions
Triple Negative Breast Cancer PDL-1 Positive
Interventions
DRUG
No Results Yet
NCT07130695 | NOT_YET_RECRUITING | PHASE1
15 Participants

Olutasidenib Single Plus Combo Therapy in IDH1mut AML After Induction and Consolidation

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2026-02-01
Completion: 2027-10-31
Conditions
Acute Myeloid Leukemia
Interventions
DRUG
No Results Yet
NCT07127016 | NOT_YET_RECRUITING | NA
24 Participants

Mindfulness in Nonflaccid Facial Paralysis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2026-05-31
Completion: 2027-01-31
Conditions
Facial Paralysis
Interventions
BEHAVIORAL
No Results Yet
NCT07120334 | RECRUITING | NA
40 Participants

Mobile Health Dietary Intervention for Stroke Survivors With Prediabetes or Type 2 Diabetes

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2025-12-15
Completion: 2026-06-30
Conditions
Stroke Recurrence Type 2 Diabetes Prediabetes
Interventions
BEHAVIORAL
No Results Yet
NCT07116447 | COMPLETED | NA
11719 Participants

Impact of Alcohol Health Messages in a Real-world Online Retail Setting

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2025-09-02
Completion: 2025-12-09
Conditions
Behaviour Change Knowledge Risk Perception Emotional Response Message Perception Intentions Sales
Interventions
BEHAVIORAL
No Results Yet
NCT07112872 | RECRUITING | PHASE2
240 Participants

A Study to Compare Different Doses of RO7795081 With a Placebo or Semaglutide in People With Type 2 Diabetes

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2025-08-19
Completion: 2027-02-08
Conditions
Type 2 Diabetes Mellitus
Interventions
DRUG
No Results Yet
NCT07112196 | RECRUITING | PHASE2/PHASE3
518 Participants

Visugromab in Cachexia International Trial

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2026-01-31
Completion: 2029-12-31
Conditions
Cancer-associated Cachexia
Interventions
DRUG
No Results Yet
NCT07111832 | RECRUITING | PHASE3
400 Participants

A Clinical Trial of SHR-A1811 in the Treatment of Triple-negative Breast Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2025-08-20
Completion: 2028-03-31
Conditions
PD-L1-positive Locally Recurrent Unresectable or Metastatic Triple-negative Breast Cancer
Interventions
DRUG
No Results Yet
NCT07108452 | NOT_YET_RECRUITING | NA
114 Participants

Using an AI Mobile Application to Promote Healthy Eating

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2026-01-31
Completion: 2026-06-30
Conditions
Healthy
Interventions
OTHER
No Results Yet
NCT07107763 | COMPLETED | NA
45 Participants

Investigation of the Effects of Short Foot Exercise and Mobilization in Young Adults With Pes Planus

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2025-09-26
Completion: 2025-12-17
Conditions
Pes Planus
Interventions
OTHER COMBINATION_PRODUCT
No Results Yet
NCT07106580 | RECRUITING | PHASE1/PHASE2
48 Participants

Safety and Efficacy of Lyophilized Fecal Microbiota Transplantation Via Capsules for Intestinal Multidrug-resistant Bacteria Decolonization

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2025-07-28
Completion: 2026-07-31
Conditions
Colonization, Asymptomatic
Interventions
OTHER
No Results Yet
NCT07104474 | ENROLLING_BY_INVITATION | NA
470 Participants

Adaptation and Evaluation of RESTORE

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2025-12-02
Completion: 2030-03-31
Conditions
Nurse Burnout, Healthcare Workers
Interventions
OTHER
No Results Yet
NCT07102381 | RECRUITING | PHASE2
125 Participants

A Phase 2 Neoadjuvant Study of Zanidatamab in Combination With Chemotherapy in Participants With HER2-positive Breast Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2025-09-24
Completion: 2028-01-01
Conditions
HER2-positive Breast Cancer Breast Cancer
Interventions
DRUG
No Results Yet
NCT07100860 | RECRUITING
134 Participants

The Effect of Single Lung Ventilation Duration on Postoperative Pulmonary Complications in Thoracic Surgery

Study Type: OBSERVATIONAL
Last Updated: 2025-12-18
Start Date: 2025-01-01
Completion: 2025-12-01
Conditions
Postoperative Pulmonary Complications One Lung Ventilation Ards Postoperative Pulmonary Atelectasis
Interventions
PROCEDURE
No Results Yet
NCT07099989 | RECRUITING | PHASE1
32 Participants

Pharmacokinetics of GATE-251 in Fasted or Fed State

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2025-07-24
Completion: 2026-01-31
Conditions
Healthy Volunteers in Fed and Fasted State
Interventions
DRUG
No Results Yet
NCT07092293 | RECRUITING
90 Participants

Studying Rehabilitation Treatments Using Video to Improve Recovery for Adults With Physical Disabilities

Study Type: OBSERVATIONAL
Last Updated: 2025-12-18
Start Date: 2025-02-11
Completion: 2026-07-31
Conditions
Stroke Spinal Cord Injury Occupational Therapy
Interventions
OTHER
No Results Yet
NCT07086079 | COMPLETED | PHASE1
12 Participants

A Study of Doravirine/Islatravir in Healthy Lactating Females (MK-8591A-061)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2025-09-26
Completion: 2025-12-11
Conditions
Healthy
Interventions
DRUG
No Results Yet
NCT07083128 | RECRUITING
64 Participants

Temporal Change in Parasternal Thickening Fraction as a Predictor for Weaning

Study Type: OBSERVATIONAL
Last Updated: 2025-12-18
Start Date: 2025-07-13
Completion: 2026-03-01
Conditions
Mechanical Ventilation Weaning From Mechanical Ventilation Weaning Failure
Interventions
DEVICE
No Results Yet
NCT07079826 | NOT_YET_RECRUITING | NA
50 Participants

Sparrow Link Neuromodulation Device for Opioid Withdrawal Management in Hospitalized Adults With Opioid Use Disorder

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2026-02-21
Completion: 2026-06-30
Conditions
Opioid Withdrawal Opioid Use Disorder (OUD)
Interventions
DEVICE
No Results Yet
NCT07076654 | COMPLETED | NA
90 Participants

Oral Caffeine and Spinal-Induced Hypotension

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2025-07-12
Completion: 2025-10-01
Conditions
Spinal Hypotension Caffeine
Interventions
DRUG
No Results Yet
NCT07076550 | RECRUITING | PHASE1
50 Participants

A Phase 1-1b Study to Evaluate the Safety, Efficacy and Dosimetry of Study Drug A9-3408 in Subjects With Metastatic Melanoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2025-11-19
Completion: 2028-01-31
Conditions
Melanoma Metastatic Uveal Melanoma, Metastatic Mucosal Melanoma
Interventions
DRUG DIAGNOSTIC_TEST
No Results Yet
NCT07076108 | COMPLETED | NA
60 Participants

Oral Vitamin C Administration on Erythropoietin Dosing Requirement in End-Stage Renal Disease Patients on Regular Hemodialysis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2019-08-01
Completion: 2024-04-28
Conditions
Vitamin C Oral Administration Erythropoietin End-Stage Renal Disease Regular Hemodialysis
Interventions
DRUG
No Results Yet
NCT07073950 | RECRUITING | PHASE4
56 Participants

A Study to Investigate the Effect of Budesonide/Glycopyrronium/Formoterol Fumarate Metered Dose Inhaler (BGF MDI) Compared With Placebo MDI on Heart and Lung Function in Participants With Chronic Obstructive Pulmonary Disease (COPD)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2025-11-24
Completion: 2027-03-31
Conditions
Chronic Obstructive Pulmonary Disease Hyperinflation
Interventions
DRUG DEVICE
No Results Yet
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