Mobile Health Dietary Intervention for Stroke Survivors With Prediabetes or Type 2 Diabetes

NCT ID: NCT07120334

Last Updated: 2025-12-18

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

40 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-12-15

Study Completion Date

2026-06-30

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

Objectives: This study aims to test whether a mobile app called PortionSize Ed can help adults who have had a recent stroke and also have prediabetes or type 2 diabetes improve their diet. Specifically, we want to see if the app can help people follow a Mediterranean-style diet, which may lower the risk of future strokes and improve overall health.

The main goals are to:

* Test if the app is easy to use and acceptable to participants.
* See whether the app helps people follow a healthier diet.
* Look at changes in health indicators like blood sugar, cholesterol, blood pressure, and body fat.

Design and Outcome:

This is a randomized controlled pilot study that will involve 40 participants. All participants will be recruited from Queen's Medical Center after a recent stroke and will be randomly assigned to one of two groups:

Intervention Group: Uses the full PortionSize Ed app, gets weekly reminders and educational videos, and has 3 sessions with a registered dietitian (RDN) over 12 weeks.

Control Group: Uses a basic version of the app without feedback or RDN support, and receives usual care for stroke recovery.

All participants will continue to receive standard care from Queen's, including the My Stroke Recovery Guide. The study lasts 12 weeks, with visits at the beginning and end to collect health data and feedback on the app.

Schedule and Type of Evaluations/Interventions:

Participants will complete the following:

Baseline and Week 12 Visits: In-person assessments for blood sugar (HbA1c), cholesterol, blood pressure, height, weight, and body composition (using DXA, BIA, and 3D imaging), as well as surveys about their diet and activity levels.

Intervention Group Only:

* Three virtual counseling sessions with a registered dietitian (Week 1, 6, 12)
* Weekly nutrition goal tracking and texting with the dietitian
* Watching short educational videos through the app
* Receiving app-based feedback on how well their diet follows Mediterranean Diet recommendations

Duration of Study: The study will last 12 weeks for each participant, with an optional long-term follow-up using medical records.

Sample Size and Population: The study will include 40 adults, ages 30 to 65, who:

* Recently experienced a stroke
* Have a history of prediabetes or type 2 diabetes
* Are medically stable and able to use a smartphone (or willing to use a study-provided iPhone)
* People will be excluded if they have severe swallowing issues, cognitive problems, or dietary needs that would make it hard to follow a Mediterranean-style diet.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Study Visits:

Baseline Visit (Week 0) at UHCC - All Participants:

* Consent form signed and randomization to a study group
* Fingerstick blood test to measure HbA1c and lipid levels
* Height, weight, blood pressure, and body composition measurements using DXA, BIA, and 3D Optical Scan
* Questionnaires: Demographics, physical activity (IPAQ-SF), Mediterranean Diet adherence (MEDAS), and current medications
* PortionSize Ed app training and 3-day food logging using the app
* Pregnancy test (urine) for participants of childbearing potential
* Counseling with the registered dietitian (\~30-60 minutes) (Intervention only)
* Receive study stipend ($50)

Week 6 Visit, Virtual Visit:

* Follow-up questionnaires and review of app engagement (Intervention only)
* Counseling with the registered dietitian (\~30-60 minutes) (Intervention only)
* Review of medications and dietary services received
* Self-reported adherence and barriers to diet change (Intervention only)
* Receive study stipend ($60)

Week 12 Visit at UHCC - All Participants:

* Repeat body composition measurements (DXA, BIA, 3DO)
* Repeat fingerstick blood tests (HbA1c and lipids)
* Final questionnaires and MEDAS
* Final 3-day food record
* Satisfaction and usability surveys
* Counseling with the registered dietitian (\~30-60 minutes) (Intervention only)
* Return study iPhone (if applicable)
* Receive study stipend ($90)

Between visits for intervention group only:

* Log one day food intake per week (\~10-15 minutes)
* Text weekly dietary goal (\~5 minutes)
* Watch a short nutrition video each week (\~3 minutes)
* Weekly reminders to complete a 1-day food log/week between study visits

Between visits for Active Comparator Group:

• Basic version of the app (no real-time feedback or counseling) and continue usual care, including the My Stroke Recovery Guide.

Length of Time in this Study:

Participation in this study will last approximately 12 weeks

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Stroke Recurrence Type 2 Diabetes Prediabetes

Keywords

Explore important study keywords that can help with search, categorization, and topic discovery.

PortionSize Ed Stroke Diabetes Prediabetes Type 2 Diabetes T2D Mediterranean Diet mHealth Hawaii

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

NONE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

PortionSize Ed + MedDiet Support

Full PortionSize Ed app access with personalized dietary feedback, educational videos, 3 virtual sessions with a registered dietitian (RDN), standard of care (for post-stroke with pre-diabetes or T2D) over 12 weeks.

Group Type EXPERIMENTAL

PortionSize Ed + MedDiet Support

Intervention Type BEHAVIORAL

Full PortionSize Ed app access with personalized dietary feedback, educational videos, 3 virtual sessions with a registered dietitian (RDN), standard of care (for post-stroke with pre-diabetes or T2D) over 12 weeks.

Standard of Care

Uses a basic version of the app without feedback or RDN support and receives usual care for stroke recovery for 12 weeks.

Group Type ACTIVE_COMPARATOR

Standard of care for Stroke and Prediabetes or T2D

Intervention Type BEHAVIORAL

Uses a basic version of the PortionSize Ed app without feedback or RDN support and receives usual care for stroke recovery and prediabetes or T2D for 12 weeks.

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

PortionSize Ed + MedDiet Support

Full PortionSize Ed app access with personalized dietary feedback, educational videos, 3 virtual sessions with a registered dietitian (RDN), standard of care (for post-stroke with pre-diabetes or T2D) over 12 weeks.

Intervention Type BEHAVIORAL

Standard of care for Stroke and Prediabetes or T2D

Uses a basic version of the PortionSize Ed app without feedback or RDN support and receives usual care for stroke recovery and prediabetes or T2D for 12 weeks.

Intervention Type BEHAVIORAL

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Aged 30 to 65 years
* Recent stroke (ischemic or hemorrhagic), within 1-14 days prior to enrollment
* Confirmed diagnosis of prediabetes or type 2 diabetes, based on HbA1c results
* Medically stable and cleared for oral diet and physical activity by the attending physician
* Cleared for thin liquids and regular textures by physician
* Capable of providing informed consent
* Able to speak and read English
* Owns a smartphone OR is willing to use a study-provided iPhone
* Has sufficient cognitive and physical function to use a mobile app
* Willing to participate in all study procedures and available for the 12-week duration

Exclusion Criteria

* Severe dysphagia that prevents oral intake
* Type 1 diabetes
* Cognitive impairment (e.g., dementia, post-stroke confusion) that precludes consent or compliance, as judged by the clinical care team
* Current participation in another interventional clinical trial
* Pregnant or breastfeeding, or planning to become pregnant during the study period
* Unwilling or unable to provide written informed consent
* Serious comorbid conditions that, in the opinion of the
Minimum Eligible Age

30 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Queen's Medical Center

OTHER

Sponsor Role collaborator

University of Hawaii

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Responsibility Role SPONSOR

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

University of Hawaii Cancer Center

Honolulu, Hawaii, United States

Site Status RECRUITING

Countries

Review the countries where the study has at least one active or historical site.

United States

Central Contacts

Reach out to these primary contacts for questions about participation or study logistics.

Chloe P Lozano, PhD, MS, GradDip Dietetics

Role: CONTACT

Phone: (808) 586-3010

Email: [email protected]

Facility Contacts

Find local site contact details for specific facilities participating in the trial.

Chloe P Lozano, PhD, MS, GradDip Dietetics

Role: primary

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

RA-2025-302

Identifier Type: -

Identifier Source: org_study_id