Clinical Trials
Showing trials with last updates posted in 2025.
470
Participants
Adaptation and Evaluation of RESTORE
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2025-12-02
Completion:
2030-03-31
Conditions
Nurse
Burnout, Healthcare Workers
Interventions
OTHER
No Results Yet
125
Participants
A Phase 2 Neoadjuvant Study of Zanidatamab in Combination With Chemotherapy in Participants With HER2-positive Breast Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2025-09-24
Completion:
2028-01-01
Conditions
HER2-positive Breast Cancer
Breast Cancer
Interventions
DRUG
No Results Yet
134
Participants
The Effect of Single Lung Ventilation Duration on Postoperative Pulmonary Complications in Thoracic Surgery
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-18
Start Date:
2025-01-01
Completion:
2025-12-01
Conditions
Postoperative Pulmonary Complications
One Lung Ventilation
Ards
Postoperative Pulmonary Atelectasis
Interventions
PROCEDURE
No Results Yet
32
Participants
Pharmacokinetics of GATE-251 in Fasted or Fed State
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2025-07-24
Completion:
2026-01-31
Conditions
Healthy Volunteers in Fed and Fasted State
Interventions
DRUG
No Results Yet
90
Participants
Studying Rehabilitation Treatments Using Video to Improve Recovery for Adults With Physical Disabilities
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-18
Start Date:
2025-02-11
Completion:
2026-07-31
Conditions
Stroke
Spinal Cord Injury
Occupational Therapy
Interventions
OTHER
No Results Yet
12
Participants
A Study of Doravirine/Islatravir in Healthy Lactating Females (MK-8591A-061)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2025-09-26
Completion:
2025-12-11
Conditions
Healthy
Interventions
DRUG
No Results Yet
64
Participants
Temporal Change in Parasternal Thickening Fraction as a Predictor for Weaning
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-18
Start Date:
2025-07-13
Completion:
2026-03-01
Conditions
Mechanical Ventilation
Weaning From Mechanical Ventilation
Weaning Failure
Interventions
DEVICE
No Results Yet
50
Participants
Sparrow Link Neuromodulation Device for Opioid Withdrawal Management in Hospitalized Adults With Opioid Use Disorder
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2026-02-21
Completion:
2026-06-30
Conditions
Opioid Withdrawal
Opioid Use Disorder (OUD)
Interventions
DEVICE
No Results Yet
90
Participants
Oral Caffeine and Spinal-Induced Hypotension
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2025-07-12
Completion:
2025-10-01
Conditions
Spinal Hypotension
Caffeine
Interventions
DRUG
No Results Yet
50
Participants
A Phase 1-1b Study to Evaluate the Safety, Efficacy and Dosimetry of Study Drug A9-3408 in Subjects With Metastatic Melanoma
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2025-11-19
Completion:
2028-01-31
Conditions
Melanoma Metastatic
Uveal Melanoma, Metastatic
Mucosal Melanoma
Interventions
DRUG
DIAGNOSTIC_TEST
No Results Yet
60
Participants
Oral Vitamin C Administration on Erythropoietin Dosing Requirement in End-Stage Renal Disease Patients on Regular Hemodialysis
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2019-08-01
Completion:
2024-04-28
Conditions
Vitamin C
Oral Administration
Erythropoietin
End-Stage Renal Disease
Regular Hemodialysis
Interventions
DRUG
No Results Yet
56
Participants
A Study to Investigate the Effect of Budesonide/Glycopyrronium/Formoterol Fumarate Metered Dose Inhaler (BGF MDI) Compared With Placebo MDI on Heart and Lung Function in Participants With Chronic Obstructive Pulmonary Disease (COPD)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2025-11-24
Completion:
2027-03-31
Conditions
Chronic Obstructive Pulmonary Disease
Hyperinflation
Interventions
DRUG
DEVICE
No Results Yet
18
Participants
Momelotinib in Combination With Hypomethylating Agent for Chronic Phase Myelodysplastic Syndromes/Myeloproliferative Overlap Neoplasms and Chronic Neutrophilic Leukemia
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2026-01-05
Completion:
2027-12-05
Conditions
Chronic Myelomonocytic Leukemia
Myelodysplastic Syndromes
Myeloproliferative Overlap Neoplasms
Chronic Neutrophilic Leukemia
Interventions
DRUG
No Results Yet
56
Participants
Simplified Onboarding in Adults With Type 2 Diabetes
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2025-07-18
Completion:
2026-01-31
Conditions
Type 2 Diabetes Mellitus
Interventions
DEVICE
No Results Yet
50
Participants
Effect of Maternal Voice on Physiological Indicators and Feeding Performance
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2025-08-10
Completion:
2026-07-23
Conditions
Preterm
Oral Feeding Performance
Interventions
PROCEDURE
OTHER
No Results Yet
32
Participants
A Phase 1 Study of JADE101 in Healthy Participants
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2025-08-17
Completion:
2026-10-31
Conditions
Healthy Volunteers
Interventions
DRUG
No Results Yet
0
Participants
Phase III Trial of SGLT2 Inhibitor and Thiazolidinedione Fixed-Dose Combination vs. Monotherapy in Type 2 Diabetes Patients on Metformin
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2026-09-30
Completion:
2028-02-29
Conditions
Type 2 Diabetes Mellitus (T2DM)
Interventions
DRUG
No Results Yet
104
Participants
A Study to Evaluate Concomitant Perfluorohexyloctane Use With Contact Lens Wear
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2025-07-02
Completion:
2025-11-03
Conditions
Dry Eye
Interventions
DRUG
No Results Yet
48
Participants
Evaluating Glucose Control Using a Next Generation Automated Insulin Delivery Algorithm in Adults With Type 2 Diabetes
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2025-07-01
Completion:
2026-03-31
Conditions
Diabetes Mellitus
Interventions
DEVICE
No Results Yet
3500
Participants
Early Detection of Type 1 Diabetes in First Degree Relatives of Type 1 Diabetes Patients (DETECT T1D GULF)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2025-12-25
Completion:
2026-12-25
Conditions
Type 1 Diabetes
Interventions
PROCEDURE
No Results Yet
874
Participants
Reducing the Resection Range After Neoadjuvant Therapy for Locally Advanced Upper Rectal and Rectosigmoid Junction Cancers
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2025-07-01
Completion:
2027-06-20
Conditions
Locally Advanced Rectal Carcinoma
Interventions
PROCEDURE
OTHER
No Results Yet
138
Participants
DeepPriorCBCT for Low Dose Lung CBCT Reconstruction
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2025-05-15
Completion:
2025-07-15
Conditions
Lung Nodules
Interventions
RADIATION
No Results Yet
50
Participants
Transcranial Magnetic Stimulation for Chronic Scrotal Content Pain
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2026-02-10
Completion:
2030-04-01
Conditions
Scrotal Pain
Interventions
OTHER
No Results Yet
586
Participants
A Study of Retatrutide (LY3437943) in Participants Who Have Obesity or Overweight and Chronic Low Back Pain
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2025-05-29
Completion:
2027-09-30
Conditions
Obesity
Overweight
Chronic Low Back Pain (CLBP)
Interventions
DRUG
No Results Yet
12
Participants
Peds CHAMP1ON - Hematopoietic Stem Cell And Monoclonal Antibody PD-1 Blockade for RecurreNt Pediatric High-Grade Glioma
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2025-07-25
Completion:
2030-12-31
Conditions
Recurrent High-grade Glioma
Grade III Astrocytoma
Oligodendroglioma
Oligoastrocytoma
Ependymoma
Grade IV Astrocytoma
Interventions
BIOLOGICAL
DRUG
PROCEDURE
No Results Yet
30
Participants
A Study to Evaluate the Safety and Efficacy of OPB-101 in Platinum-resistant Ovarian Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2025-06-16
Completion:
2028-05-15
Conditions
Ovarian Cancer Recurrent
Ovarian Cancer
Platinum Resistant Ovarian Cancer
Interventions
BIOLOGICAL
No Results Yet
27
Participants
Investigation of Inspiratory Muscle Training Applied at Different Intensities on Intercostal Muscle Oxygenation
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2025-07-23
Completion:
2025-12-23
Conditions
Healthy
Interventions
DEVICE
OTHER
No Results Yet
48
Participants
Investigation of the Effects of Lumbopelvic Movement Training on Different Parameters in Healthy Sedentary Individuals
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2025-06-04
Completion:
2025-11-29
Conditions
Exercise Training
Interventions
OTHER
No Results Yet
170
Participants
Effect of Deep Analgosedation vs. Endotracheal Intubation General Anesthesia on on Perioperative Sedation Related Adverse Events in Elderly ERCP Patients
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2025-11-10
Completion:
2026-02-28
Conditions
Biliary and Pancreatic Diseases
Endoscopic Retrograde Cholangiopancreatography (ERCP)
Interventions
DEVICE
No Results Yet
40
Participants
SH+ and Cash Assistance
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2025-06-20
Completion:
2025-08-20
Conditions
Stress
Depression Symptoms
Interventions
COMBINATION_PRODUCT
OTHER
No Results Yet
100
Participants
Assessment of Drug Liking In Peri-procedural Clinical Settings
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2025-09-30
Completion:
2026-07-31
Conditions
Drug Liking
Interventions
DRUG
No Results Yet
108
Participants
Randomized Study on Transoral Outlet Reduction and Lifestyle Changes for Weight Regain After Gastric Bypass
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2026-01-31
Completion:
2026-11-30
Conditions
Weight Regain
Weight Loss
Interventions
DEVICE
BEHAVIORAL
No Results Yet
12
Participants
Optimizing Therapy in Epilepsy Using Seizure Forecasts Via EEG and Wearables
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2025-12-31
Completion:
2028-12-31
Conditions
Focal Epilepsy
Generalized Seizure
Drug Refractory Epilepsy
Interventions
DEVICE
No Results Yet
50
Participants
Treatment Decision-Making Among Patients With Chronic Rhinosinusitis
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2025-06-02
Completion:
2026-03-31
Conditions
Chronic Rhinosinusitis (CRS)
Interventions
OTHER
No Results Yet
160
Participants
A Clinical Trial for Participants With DEE to Assess Efficacy, Safety, Tolerability, and PK of Relutrigine
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2025-07-09
Completion:
2026-07-31
Conditions
Developmental and Epileptic Encephalopathy 1
Interventions
DRUG
No Results Yet
30
Participants
REACH Study (Recovery Environments: Assessing Cognitive & Brain Health in Community Mental Health)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2026-01-30
Completion:
2028-01-30
Conditions
Schizophrenia
Schizo Affective Disorder
Schizophreniform Disorders
Interventions
BEHAVIORAL
No Results Yet
90
Participants
Effects of a Yoga Program on the Functionality of Individuals
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2025-08-01
Completion:
2029-01-30
Conditions
Knee Osteoarthritis
Interventions
OTHER
No Results Yet
200
Participants
A Study to See How Well Lebrikizumab Works in Adults and Adolescents With Moderate Atopic Dermatitis (Eczema) and High Itch Burden
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2025-06-16
Completion:
2026-04-30
Conditions
Atopic Dermatitis
Interventions
DRUG
No Results Yet
46
Participants
A Study of Belumosudil in People at Risk of Developing Graft-Versus-Host Disease After a Stem Cell Transplant
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2025-05-21
Completion:
2029-05-21
Conditions
Graft Versus Host Disease
Graft Vs Host Disease
Hematologic Malignancy
Interventions
DRUG
No Results Yet
112
Participants
Effect of MGRNOX-Guided General Anesthesia on Opioid Consumption in Patients
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2025-06-28
Completion:
2026-05-30
Conditions
Opioid Use
Interventions
DEVICE
No Results Yet
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