Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
138 participants
INTERVENTIONAL
2025-05-15
2025-07-20
Brief Summary
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* Can DeepPriorCBCT reduce CBCT radiation doses?
* Is the image quality of DeepPriorCBCT reconstruction consistent with that of existing clinical reconstruction method? Researchers will compare CBCT images quality reconstruction with DeepPriorCBCT model to CBCT image quality reconstruction with existing clinical protocols to see if DeepPriorCBCT model can improve the CBCT image quality while reducing radiation dose.
Participants will:
* Receive a single low dose (1/6 of existing clinical protocols) CBCT scan
* Receive a single conventional dose CBCT scan
Detailed Description
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Conditions
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Keywords
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Study Design
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NON_RANDOMIZED
CROSSOVER
DIAGNOSTIC
DOUBLE
Study Groups
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Participants will receive a 1/6 views undersampling lung CBCT scan.
Participants will receive a 1/6 views undersampling lung CBCT scan. And the CBCT images will be reconstructed by DeepPriorCBCT model for further analysis.
Participants will receive a 1/6 views undersampling lung CBCT scan.
Participants will receive a 1/6 views undersampling lung CBCT scan. And the CBCT images will be reconstructed by DeepPriorCBCT model for further analysis.
Participants will receive a full-sampling lung CBCT scan.
Participants will receive a full-sampling lung CBCT scan. And the CBCT images will be reconstructed by current clinical method for further analysis.
No interventions assigned to this group
Interventions
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Participants will receive a 1/6 views undersampling lung CBCT scan.
Participants will receive a 1/6 views undersampling lung CBCT scan. And the CBCT images will be reconstructed by DeepPriorCBCT model for further analysis.
Eligibility Criteria
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Inclusion Criteria
2. The participants' medical records containing basic information, medical history, etc are complete.
3. Participants can understand the study's purpose, procedures, potential risks, and benefits, and voluntarily signs a written informed consent form.
Exclusion Criteria
2. Participants are suffering from severe mental illness or cognitive impairment, unable to understand the study and sign.
3. Participants are pregnant or breastfeeding women.
4. Participants are concurrent participating in other programs that affect the results of this study.
18 Years
ALL
No
Sponsors
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Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
OTHER
Responsible Party
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Locations
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The First Affiliated Hospital East Campus of Zhengzhou University
Zhengzhou, Henan, China
The First Affiliated Hospital of Zhengzhou University
Zhengzhou, Henan, China
Wuhan Union Hospital
Wuhan, Hubei, China
Wuhan Union Jinyin Lake Hospital
Wuhan, Hubei, China
Wuhan Union West Hospital
Wuhan, Hubei, China
Countries
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References
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Bosch de Basea M, Thierry-Chef I, Harbron R, Hauptmann M, Byrnes G, Bernier MO, Le Cornet L, Dabin J, Ferro G, Istad TS, Jahnen A, Lee C, Maccia C, Malchair F, Olerud H, Simon SL, Figuerola J, Peiro A, Engels H, Johansen C, Blettner M, Kaijser M, Kjaerheim K, Berrington de Gonzalez A, Journy N, Meulepas JM, Moissonnier M, Nordenskjold A, Pokora R, Ronckers C, Schuz J, Kesminiene A, Cardis E. Risk of hematological malignancies from CT radiation exposure in children, adolescents and young adults. Nat Med. 2023 Dec;29(12):3111-3119. doi: 10.1038/s41591-023-02620-0. Epub 2023 Nov 9.
Mazzone PJ, Lam L. Evaluating the Patient With a Pulmonary Nodule: A Review. JAMA. 2022 Jan 18;327(3):264-273. doi: 10.1001/jama.2021.24287.
Other Identifiers
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DeepPriorCBCT001
Identifier Type: -
Identifier Source: org_study_id