Clinical Trials
Showing trials with last updates posted in 2025.
76
Participants
Effect of Weekly GLP1 Agonist Treatment in "Double Diabetes"
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2022-07-12
Completion:
2028-08-31
Conditions
Double Diabetes
Interventions
DRUG
BIOLOGICAL
No Results Yet
67
Participants
Reading Intervention to Children With Developmental Language Disorder
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2021-08-01
Completion:
2023-06-30
Conditions
Developmental Language Disorder
Interventions
BEHAVIORAL
No Results Yet
400
Participants
Reliability of a Food Frequency Questionnaire in the Assessment of Dietary Intake Including FODMAPs in Different Populations, and Relationship With IBS Symptoms and the Degree of Self-assessed Physical Activity
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-18
Start Date:
2022-10-15
Completion:
2030-12-31
Conditions
Irritable Bowel Syndrome
Interventions
OTHER
No Results Yet
500
Participants
The DISCOVER INOCA Prospective Multi-center Registry
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-18
Start Date:
2022-09-14
Completion:
2032-12-31
Conditions
Ischemia and No Obstructive Coronary Artery Disease
Coronary Microvascular Dysfunction
Coronary Vasospasm
Endothelial Dysfunction
Microvascular Angina
Chest Pain With Normal Coronary Angiography
Interventions
DIAGNOSTIC_TEST
No Results Yet
18
Participants
Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ASC61in Subjects With Advanced Solid Tumors
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2022-08-02
Completion:
2025-01-17
Conditions
Advanced Solid Tumors
Interventions
DRUG
No Results Yet
600
Participants
Addressing Risk Through Community Treatment for Infectious Disease and Opioid Use Disorder Now (ACTION) Among Justice-involved Populations
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2022-03-31
Completion:
2025-07-31
Conditions
Opioid Use Disorder
Infectious Disease
Risk Reduction Behavior
Substance Use
Substance Abuse
Stimulant Use Disorder
Interventions
BEHAVIORAL
No Results Yet
117
Participants
Brain Health in Youth With Normal Weight, Overweight and Obesity at Risk for Type 2 Diabetes (T2D)
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-18
Start Date:
2022-05-24
Completion:
2026-10-31
Conditions
Type2 Diabetes
Type 2 Diabetes Mellitus in Obese
Dysglycemia
Microvascular Complications
Brain Structure
Obesity, Childhood
Diabetes in Adolescence
Inflammation
Insulin Resistance
Overweight, Childhood
Cognitive Decline
Interventions
OTHER
No Results Yet
200
Participants
INTO-HLH: A Disease Registry for Patients With Hemophagocytic Lymphohistiocytosis (HLH)
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-18
Start Date:
2021-12-31
Completion:
2026-01-31
Conditions
Hemophagocytic Lymphohistiocytoses
No Results Yet
60
Participants
Descemet Endothelial Thickness Comparison Trial II
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2023-01-23
Completion:
2027-11-30
Conditions
Fuchs
Fuchs Dystrophy
Fuchs' Endothelial Dystrophy
Interventions
DRUG
No Results Yet
86
Participants
Necessity of Fusion Following Decompression Surgery in Patients With Single-level Lumbar Stenosis
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2022-04-01
Completion:
2026-12-30
Conditions
Lumbar Spinal Stenosis
Spinal Stenosis
Spinal Fusion
Interventions
PROCEDURE
No Results Yet
500
Participants
Studying Pathways of Resistance in KRAS-driven Cancers
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-18
Start Date:
2022-09-08
Completion:
2025-12-10
Conditions
KRAS P.G12C
Interventions
DIAGNOSTIC_TEST
No Results Yet
414
Participants
A Study of KL590586 in Patients With Advanced Solid Tumors
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2021-09-15
Completion:
2026-12-31
Conditions
Advanced Solid Tumor
Interventions
DRUG
No Results Yet
759
Participants
A Study of Daratumumab, Bortezomib, Lenalidomide and Dexamethasone (DVRd) Followed by Ciltacabtagene Autoleucel Versus Daratumumab, Bortezomib, Lenalidomide and Dexamethasone (DVRd) Followed by Autologous Stem Cell Transplant (ASCT) in Participants With Newly Diagnosed Multiple Myeloma
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2023-10-10
Completion:
2033-06-30
Conditions
Multiple Myeloma
Interventions
DRUG
No Results Yet
69
Participants
Retrospective Evaluation of Guided Growth Plate System Plus's Safety and Clinical Performance for the Treatment of Lower Limbs Deformities.
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-18
Start Date:
2021-11-16
Completion:
2022-01-24
Conditions
Genu Varum
Genu Valgum
Joint Diseases
Knee Deformity
Ankle Deformity
Length Inequality, Leg
Discrepancy Length; Congenital
Deformity of Limb
Interventions
DEVICE
116
Participants
A Phase 1 Study of RO7623066 Alone and in Combination in Patients With Advanced Solid Tumors
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2021-08-26
Completion:
2025-11-26
Conditions
Advanced Solid Tumors
Interventions
DRUG
No Results Yet
160
Participants
HOme-Based Self-management and COgnitive Training CHanges Lives (HOBSCOTCH) -Post-Traumatic Epilepsy (PTE)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2022-03-21
Completion:
2025-10-31
Conditions
Epilepsy, Traumatic
Brain Injuries, Traumatic
Interventions
BEHAVIORAL
No Results Yet
112
Participants
Pharmaco-Neuroimaging Studies of Approach/Avoidance Behaviors and Post-Mortem Studies: Pharmacological Manipulation
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2025-02-01
Completion:
2026-03-31
Conditions
Depressive Disorder, Major
Anxiety Disorder
Interventions
DRUG
DEVICE
No Results Yet
10
Participants
A Study to Evaluate the Safety of AB-1003 (Previously LION-101) in Subjects With Genetic Confirmation of LGMD2I/R9 (Part1)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2023-05-15
Completion:
2028-12-31
Conditions
Fukutin Related Protein
Limb Girdle Muscular Dystrophy
Limb-Girdle Muscular Dystrophy Type 2
LGMD2I
Muscular Dystrophy
LGMD2
LGMD
FKRP
FKRP Mutation
Interventions
GENETIC
OTHER
No Results Yet
60
Participants
Efficacy of Adding Lower Extremity Weights on Balance in Children With Ataxic Cerebral Palsy
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2025-01-05
Completion:
2025-12-15
Conditions
Ataxic Cerebral Palsy
Interventions
OTHER
No Results Yet
56
Participants
Utilizing MyChart to Assess the Effectiveness of Interventions for Vasomotor Symptoms: A Feasibility Study
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2022-02-25
Completion:
2022-07-22
Conditions
Breast Cancer
Interventions
OTHER
No Results Yet
43
Participants
Acute and Chronic Pain After One-stage Hybrid Arrhythmia Ablation Surgery
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2023-02-01
Completion:
2025-06-01
Conditions
Arrythmia
Chronic Pain
Acute Pain
Post Operative Pain
Interventions
OTHER
No Results Yet
0
Participants
A Phase 3, Double-blind/Double-dummy, Safety/Efficacy/Superiority of Sibutramine/Topiramate XR in Adults With Overweight
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2026-04-30
Completion:
2028-03-31
Conditions
Overweight
Obesity
Interventions
DRUG
No Results Yet
315
Participants
A Study of PF-08046054/SGN-PDL1V in Advanced Solid Tumors
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2022-10-25
Completion:
2027-04-09
Conditions
Carcinoma, Non-Small-Cell Lung
Squamous Cell Carcinoma of the Head and Neck
Esophageal Squamous Cell Carcinoma
Ovarian Neoplasms
Melanoma
Triple Negative Breast Neoplasms
Gastric Cancer
Interventions
DRUG
No Results Yet
46
Participants
The FLOTILLA Study: Providing Continued Access to The Study Medicines Encorafenib and Binimetinib for Participants in Prior Clinical Trials
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2022-07-05
Completion:
2029-07-31
Conditions
Solid Tumors
Interventions
DRUG
No Results Yet
50
Participants
Free From Maintenance Drug Therapy in Multiple Myeloma (The FREEDMM Trial) for Minimal Residual Disease (MRD
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2021-12-31
Completion:
2029-01-31
Conditions
Multiple Myeloma
Interventions
OTHER
No Results Yet
34
Participants
Effectiveness of a Powered Exoskeleton Combined With FES for Patients With Chronic SCI: a RCT
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2022-03-18
Completion:
2027-12-31
Conditions
Spinal Cord Injuries
Gait Disorders, Neurologic
Interventions
DEVICE
No Results Yet
444
Participants
Surgery Versus Stereotactic Body Radiation Therapy for Stage I Non-Small Cell Lung Cancer
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-18
Start Date:
2022-07-14
Completion:
2029-01-31
Conditions
Non Small Cell Lung Cancer
Non-small Cell Lung Cancer
No Results Yet
33
Participants
Paxalisib With a High Fat, Low Carb Diet and Metformin for Glioblastoma
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2022-02-14
Completion:
2026-06-30
Conditions
Glioblastoma
Interventions
DRUG
OTHER
No Results Yet
18
Participants
Neoadjuvant HAIC of TACE Plus Donafenib in BCLC B Stage HCC: a Multi-center Randomized Controlled Trial.
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2021-12-24
Completion:
2025-10-31
Conditions
Hepatocellular Carcinoma
Interventions
PROCEDURE
DRUG
No Results Yet
71
Participants
Randomized Double-Blind Placebo-Controlled Adaptive Design Trial Of Intrathecally Administered Autologous Mesenchymal Stem Cells In Multiple System Atrophy
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2021-12-15
Completion:
2026-12-31
Conditions
Multiple System Atrophy
Interventions
BIOLOGICAL
OTHER
No Results Yet
72
Participants
Preoperative Mindfulness: Minimally Invasive Hysterectomy
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2023-06-20
Completion:
2025-12-31
Conditions
Pain, Postoperative
Interventions
BEHAVIORAL
No Results Yet
234
Participants
Mobile & Online-Based Interventions to Lessen Pain
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2023-08-23
Completion:
2025-08-15
Conditions
Chronic Pain
Opioid Misuse
Opioid Use Disorder
Interventions
BEHAVIORAL
No Results Yet
0
Participants
Tracking Biomarkers of Speech Intelligibility
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2022-01-31
Completion:
2022-12-31
Conditions
High-Frequency Hearing Loss
Interventions
BEHAVIORAL
No Results Yet
200
Participants
Surveying the Receptivity for Telemedicine Pre-operative Consultation in UZ Brussel.
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2023-03-15
Completion:
2023-08-31
Conditions
Remote Consultation
Interventions
OTHER
No Results Yet
180
Participants
OurRelationship for Veteran Couples
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2023-02-06
Completion:
2026-10-31
Conditions
Relationship Distress
Interventions
BEHAVIORAL
No Results Yet
400
Participants
De-convoluting Interactions Between Genes, the Cancer Environment, and the Immune System to Develop Therapies That Work for You
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-18
Start Date:
2022-01-12
Completion:
2027-12-31
Conditions
Breast Cancer
Interventions
PROCEDURE
No Results Yet
350
Participants
Estimation of the Prevalence of HIV, Hepatitis C and Hepatitis B Infection Among Detainees in the Nîmes Administrative Detention Center
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2022-02-08
Completion:
2022-12-07
Conditions
HIV Infections
Hepatitis C
Hepatitis B
Interventions
DIAGNOSTIC_TEST
No Results Yet
60
Participants
Efficacy of a Low FODMAP Diet in the Absence of Lactose Malabsorption in Moderate to Severe ROME IV IBS.
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2021-11-02
Completion:
2028-01-31
Conditions
Irritable Bowel Syndrome
Interventions
OTHER
No Results Yet
30
Participants
Hypofractionated vs Conventional Fractionated RT in Soft Tissue Sarcomas
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2022-04-06
Completion:
2026-11-30
Conditions
Soft Tissue Sarcoma
Interventions
RADIATION
No Results Yet
5399
Participants
International Study on COVID-19 Vaccine to Assess Immunogenicity, Reactogenicity and Efficacy (InVITE)
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-18
Start Date:
2021-08-16
Completion:
2025-08-19
Conditions
COVID-19
No Results Yet
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