Clinical Trials
Showing trials with last updates posted in 2025.
25
Participants
The Efficacy and Safety of Iparomlimab and Tuvonralimab Injection Combined With Chemotherapy as the First-line Treatment for Esophageal Squamous Cell Carcinoma
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-17
Start Date:
2025-09-26
Completion:
2026-12-31
Conditions
Esophageal Squamous Cell Carcinoma (ESCC)
Interventions
DRUG
No Results Yet
39
Participants
Iparomlimab and Tuvonralimab Combined With Apatinib and Irinotecan Hydrochloride for the Treatment of Advanced Alpha-fetoprotein-producing Gastric Cancer (AFPGC)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-17
Start Date:
2025-09-28
Completion:
2027-09-30
Conditions
AFP Gastric or Gastroesophageal Junction Adenocarcinoma
PD-1/CTLA-4
AFPGC
Immunotherapy
Interventions
DRUG
No Results Yet
50
Participants
Correlation Between Diagnostic Nerve Block Response and Cryoneurolysis Outcome in Chronic Musculoskeletal Disorders and Spasticity
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-17
Start Date:
2026-02-01
Completion:
2030-05-01
Conditions
Spasticity
Chronic Musculoskeletal Pain
Cryo Analgesia
Cryoablation
Interventions
PROCEDURE
No Results Yet
52
Participants
Effects of Respiratory Muscle Training in Post-bariatric Surgery Patients
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-17
Start Date:
2026-01-05
Completion:
2027-06-30
Conditions
Bariatric Surgery
Interventions
BEHAVIORAL
OTHER
No Results Yet
81
Participants
Effects of Sevoflurane vs Desflurane on Early Recovery and Cognitive Function in Elderly Patients Undergoing Scheduled Non-Cardiac Surgery
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-17
Start Date:
2024-09-15
Completion:
2025-04-15
Conditions
Early Recovery in Elderly Patients
Cognitive Function
Interventions
DRUG
No Results Yet
38
Participants
"Clinical Evaluation of Self-Assembling Peptides Versus Tri-Calcium Phosphate Based Varnish in Treatment of White Spot Lesions; Split-Mouth Randomized Clinical Trial"
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-17
Start Date:
2024-02-20
Completion:
2024-11-20
Conditions
White Spot Lesions
Interventions
OTHER
No Results Yet
15
Participants
Exploring Sustainable Alternatives to Marine Oils With Echium and Ahiflower Oils
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-17
Start Date:
2025-05-26
Completion:
2026-03-05
Conditions
Cardiovascular (CV) Risk
Atheroscleroses
Inflamation
Omega 3 Fatty Acids
Supplement
Interventions
DIETARY_SUPPLEMENT
No Results Yet
40
Participants
Measurement of Mass Change in Serum Albumin Compared to Serum Lactic Acid as Predictive Tool for Sepsis Prognosis in Non Surgical ICU Patients
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-17
Start Date:
2025-09-28
Completion:
2026-09-28
Conditions
Prognosis Prediction of Sepsis in Icu Patients
Interventions
DIAGNOSTIC_TEST
No Results Yet
38
Participants
Investigation of the Effects of Kettlebell Training
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-17
Start Date:
2024-11-25
Completion:
2025-12-31
Conditions
Shoulder Pain
Rotator Cuff Injuries
Interventions
OTHER
No Results Yet
40
Participants
Nutritional Effects of Supplementing Nonagenarians With a Supplement Based on a Fruit From the Cerrado: Buriti
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-17
Start Date:
2024-05-01
Completion:
2024-08-26
Conditions
Malnutrition in the Elderly
Interventions
DIETARY_SUPPLEMENT
No Results Yet
108
Participants
Prediction of Lower Extremity Injuries Using Lower Limb-worn Inertial Measurement Units
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-17
Start Date:
2024-01-29
Completion:
2024-06-04
Conditions
Lower Extremity Injuries
Interventions
OTHER
No Results Yet
232
Participants
Construction and Application of an Intelligent Collaborative Cardiac Rehabilitation App for Middle-aged and Young Patients With Myocardial Infarction
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-17
Start Date:
2026-01-01
Completion:
2028-12-31
Conditions
Myocardial Infarction
Cardiac Rehabilitation
APP
Interventions
BEHAVIORAL
No Results Yet
300
Participants
Safety and Efficacy of the 3DMax™ MID Anatomical Mesh (BD, USA) in Laparoscopic-endoscopic Inguinal Hernia Repair - Multicenter, Prospective Observational Study
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-17
Start Date:
2026-01-01
Completion:
2026-04-01
Conditions
Hernia, Inguinal
Interventions
DEVICE
No Results Yet
22
Participants
Comparative Effects of Buteyko Versus Pilates Breathing Combined With McKenzie Neck Exercises on Lung Function and Chest Expansion in Asthmatic Patients With Forward Head Posture
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-17
Start Date:
2025-08-20
Completion:
2026-01-01
Conditions
Asthma
Interventions
PROCEDURE
No Results Yet
70
Participants
A First-in-human Trial of GRT7041 in Healthy Participants
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-17
Start Date:
2026-01-14
Completion:
2026-08-24
Conditions
Treatment of Pain
Interventions
DRUG
No Results Yet
75
Participants
Phase II Randomized, Open-label, Multicenter Clinical Study Evaluating the Safety, Efficacy, Pharmacokinetics, and Pharmacodynamics of SHR-2173 Injection in Patients With Primary Membranous Nephropathy
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-17
Start Date:
2026-01-31
Completion:
2027-08-31
Conditions
Primary Membranous Nephropathy
Interventions
DRUG
No Results Yet
80
Participants
The Effect of Alogliptin Combined With Actoplus Met on Glucose and Lipid Metabolism and Pancreatic Function in Patients With T2DM Complicated With MAFLD.
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-17
Start Date:
2026-02-01
Completion:
2027-08-31
Conditions
T2DM
MAFLD
Interventions
DRUG
No Results Yet
100
Participants
Clinical Study on the Therapeutic Efficacy of Biportal Endoscopic Decompression Spine Surgery and Lumbar Decompression Fusion Surgery in the Treatment of Degenerative Lumbar Spondylolisthesis
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-17
Start Date:
2025-12-10
Completion:
2030-06-30
Conditions
Lumbar Degenerative Spondylolisthesis
No Results Yet
192
Participants
Use a Wearable Devices to Observe Complications of Mobilization for Colorectal Cancer After Surgery
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-17
Start Date:
2022-08-08
Completion:
2024-01-05
Conditions
Colorectal Cancer
No Results Yet
54
Participants
Arthroscopic Repair of Partial Thickness Articular-Side Rotator Cuff Tears: Transtendon Versus Conversion Repair Techniques
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-17
Start Date:
2019-10-01
Completion:
2023-03-30
Conditions
Partial Thickness Articular-Side Rotator Cuff Tears
Interventions
PROCEDURE
No Results Yet
70
Participants
Evaluation of Postoperative Pain After Using Resin-Based and Bioceramic Sealers in Mandibular Molars With Asymptomatic Apical Periodontitis
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-17
Start Date:
2025-03-12
Completion:
2025-09-25
Conditions
Asymptomatic Apical Periodontitis
Interventions
OTHER
No Results Yet
120
Participants
Dexamethasone vs Dexmedetomidine vs Combination as Adjuvants to Popliteal Sciatic Nerve Block in Children
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-17
Start Date:
2026-01-01
Completion:
2027-01-01
Conditions
Ankle Disease
Foot Diseases
Interventions
DRUG
No Results Yet
50
Participants
Impact of Psychosocial Support Web-Based Toolkit
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-17
Start Date:
2025-08-01
Completion:
2026-01-20
Conditions
Mental Health
Self Care
Performance Enhancement
Interventions
BEHAVIORAL
No Results Yet
50
Participants
Effect of Treatment With Butyric Acid in Anorexia Nervosa
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-17
Start Date:
2025-11-12
Completion:
2026-11-12
Conditions
Anorexia Nervosa
Gut Microbiota
Weight Trajectory
Interventions
DIETARY_SUPPLEMENT
No Results Yet
140
Participants
Surgical Outcomes in Splenic Flexure Cancers: A Multicenter Comparison of Segmental vs. Extended Hemicolectomy (SPARROW Study)
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-17
Start Date:
2025-10-05
Completion:
2028-10-31
Conditions
Colon Cancer
Splenic Flexure Mobilization
Right Hemicolectomy
Left Hemicolectomy
Segmental Colectomy
Extended Hemicolectomy
Interventions
PROCEDURE
No Results Yet
40
Participants
Tailored Stapled SADI-S: Initial Report and Preliminary Results
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-17
Start Date:
2024-06-01
Completion:
2025-12-31
Conditions
Morbid Obesity
Bariatric Surgery
Malnutrition
Comorbidities
Interventions
PROCEDURE
No Results Yet
420
Participants
Phase II Clinical Trial of Lyophilized Respiratory Syncytial Virus mRNA Vaccine in Adults Aged 50 Years or Above
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-17
Start Date:
2025-09-15
Completion:
2026-01-07
Conditions
Respiratory Syncytial Virus
Interventions
BIOLOGICAL
DRUG
No Results Yet
60
Participants
COMPASS 65+ - Community-based Physical Activity Snacks for Healthy Aging in Overweight and Obese Aged Adults
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-17
Start Date:
2026-03-31
Completion:
2026-03-31
Conditions
Obesity & Overweight
Aged 65 Years or Older
Interventions
BEHAVIORAL
No Results Yet
62
Participants
Effect Of Lıstenıng to Musıc on Women Gıvıng Bırth By Cesarean Sectıon: Paın, Comfort And Attachment
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-17
Start Date:
2023-03-15
Completion:
2023-11-23
Conditions
Cesarean Delivery
Music Listening
Interventions
BEHAVIORAL
No Results Yet
96
Participants
Phase I Clinical Trial of Lyophilized Respiratory Syncytial Virus mRNA Vaccine in Adults Aged 18 Years or Above
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-17
Start Date:
2025-05-27
Completion:
2025-09-04
Conditions
Respiratory Syncytial Virus
Interventions
BIOLOGICAL
DRUG
No Results Yet
2200
Participants
Bilateral vs Unilateral Inguinal Hernia Repairs With an Asymptomatic Inguinal Hernia in Bilateral Hernias
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-17
Start Date:
2026-08-18
Completion:
2031-12-31
Conditions
Inguinal Hernia Bilateral
Interventions
PROCEDURE
No Results Yet
9
Participants
A Phase I/III Clinical Study to Evaluate NouvNeu001 Injection for Multiple System Atrophy
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-17
Start Date:
2025-12-31
Completion:
2027-07-31
Conditions
Multiple System Atrophy - Parkinsonian Subtype (MSA-P)
Interventions
BIOLOGICAL
No Results Yet
100
Participants
TLR 9 (rs352140) Gene Polymorphism in Helicobacter Pylori Infection
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-17
Start Date:
2023-01-01
Completion:
2025-05-01
Conditions
H. Pylori Infection
Interventions
DIAGNOSTIC_TEST
No Results Yet
250
Participants
The Relationship Between Enneagram Personality Types and Eating Behaviors, Emotional Eating, Psychological Well-Being, and Spirituality in Obese Individuals: A Holistic Approach
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-17
Start Date:
2025-12-31
Completion:
2026-03-01
Conditions
Obesity
Eating Behavior
Emotional Eating
No Results Yet
300
Participants
Evaluation of Survival and Clinical Outcomes of Patients Treated With Isolated All-inside Meniscal Sutures or With Meniscal Sutures Associated With Ligament Reconstruction
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-17
Start Date:
2026-01-31
Completion:
2027-12-31
Conditions
Suture, Complication
Ligament Laceration
No Results Yet
40
Participants
Is There a Benefit From Addition of Treadmill Walking to Diet Restriction in Psoriasis Women With PCOS?
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-17
Start Date:
2025-10-10
Completion:
2026-05-15
Conditions
Psoriasis
Polycystic Ovary Syndrome
Interventions
BEHAVIORAL
No Results Yet
30
Participants
Effect of IASTM in Children With Diplegia
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-17
Start Date:
2024-03-01
Completion:
2024-12-01
Conditions
Cerebral Palsy (CP)
Interventions
PROCEDURE
No Results Yet
30
Participants
Moderate Versus High-intensity Interval Training in Children With Diplegia.
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-17
Start Date:
2024-11-23
Completion:
2025-03-10
Conditions
Cerebral Palsy
Interventions
PROCEDURE
No Results Yet
30
Participants
EFFECT OF A LIGHT STIMULATED FOOTSTEPS PATHWAY ON GAIT IN SPASTIC CHILDREN
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-17
Start Date:
2025-09-20
Completion:
2025-12-20
Conditions
Spastic Diplegia
Interventions
OTHER
No Results Yet
60
Participants
Tenotomy Versus no Tenotomy LHB in Rotator Cuff Repair
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-17
Start Date:
2015-01-01
Completion:
2017-06-30
Conditions
Long Head of Biceps Brachii Lesions
Rotator Cuff Tears
Interventions
PROCEDURE
No Results Yet
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