Clinical Trials Updated in 2025

NCT07226648 | RECRUITING | NA

180 Participants

Ultrasonic Neuromodulation of Cingulate Cortex for Fibromyalgia

Study Type: INTERVENTIONAL

Last Updated: 2025-11-13

Start Date: 2025-11-30

Completion: 2026-11-30

Conditions

Fibromyalgia

Interventions

DEVICE

No Results Yet

NCT07226583 | NOT_YET_RECRUITING | NA

10 Participants

Using a Personalized Decision Support Tool to Help People With Type 1 Diabetes Manage Exercise

Study Type: INTERVENTIONAL

Last Updated: 2025-11-13

Start Date: 2025-12-31

Completion: 2026-06-30

Conditions

Type 1 Diabetes Mellitis Type 1 Diabetes (T1D) Type 1 Diabetes Mellitus (T1DM)

Interventions

BEHAVIORAL DEVICE

No Results Yet

NCT07226180 | ENROLLING_BY_INVITATION

40 Participants

Development and Application of Patient-Derived Models of Cancer

Study Type: OBSERVATIONAL

Last Updated: 2025-11-13

Start Date: 2025-11-10

Completion: 2028-09-30

Conditions

Cancer

No Results Yet

NCT07225816 | NOT_YET_RECRUITING | PHASE1

75 Participants

Examination of How the Duration of Fasting and Temporary Stopping of GLP-1 Medications Affect the Amount of Food Left in the Stomach in People Using Liraglutide (Injected), Semaglutide (Taken by Mouth) or Semaglutide (Injected)

Study Type: INTERVENTIONAL

Last Updated: 2025-11-13

Start Date: 2025-11-07

Completion: 2026-06-19

Conditions

Obesity

Interventions

DRUG

No Results Yet

NCT07225790 | ACTIVE_NOT_RECRUITING

3883 Participants

Emulation of the MONARCH-3 Trial Using Specialty Oncology Electronic Health Records Databases

Study Type: OBSERVATIONAL

Last Updated: 2025-11-13

Start Date: 2025-11-03

Completion: 2026-01-31

Conditions

Advanced Breast Cancer

Interventions

DRUG

No Results Yet

NCT07225517 | NOT_YET_RECRUITING | PHASE1

104 Participants

A Study to Learn More About the Safety of BIIB145 and How it is Processed in the Body of Healthy Adult Participants

Study Type: INTERVENTIONAL

Last Updated: 2025-11-13

Start Date: 2025-12-01

Completion: 2027-02-02

Conditions

Healthy Volunteer

Interventions

DRUG

No Results Yet

NCT07224932 | NOT_YET_RECRUITING | PHASE2

60 Participants

Tolerability and Efficacy of CBD Extract for RLS Treatment

Study Type: INTERVENTIONAL

Last Updated: 2025-11-13

Start Date: 2025-12-19

Completion: 2026-01-01

Conditions

Restless Leg Syndrome

Interventions

DRUG

No Results Yet

NCT07224334 | NOT_YET_RECRUITING | PHASE1

30 Participants

Role of Alpha-to-beta Cell Communication to Adapt Insulin Secretion to Insulin Resistance.

Study Type: INTERVENTIONAL

Last Updated: 2025-11-13

Start Date: 2025-11-30

Completion: 2026-12-31

Conditions

Diabetes (DM)

Interventions

DRUG

No Results Yet

NCT07223827 | NOT_YET_RECRUITING | NA

30 Participants

Handheld Point of Care Electro-Diagnostic Device

Study Type: INTERVENTIONAL

Last Updated: 2025-11-13

Start Date: 2025-12-31

Completion: 2026-12-31

Conditions

Neurologic Findings

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT07219589 | RECRUITING | PHASE1

40 Participants

A SAD Study of HM17321 in Healthy Adult Participants

Study Type: INTERVENTIONAL

Last Updated: 2025-11-13

Start Date: 2025-11-06

Completion: 2026-04-30

Conditions

Obesity Obese

Interventions

DRUG

No Results Yet

NCT07216690 | NOT_YET_RECRUITING | PHASE2

40 Participants

Pregnenolone as a Treatment for Cannabis Intoxication

Study Type: INTERVENTIONAL

Last Updated: 2025-11-13

Start Date: 2026-01-05

Completion: 2028-01-01

Conditions

Cannabis Intoxication

Interventions

DRUG

No Results Yet

NCT07216105 | RECRUITING | PHASE1

113 Participants

FT836 With or Without Chemotherapy and/or Monoclonal Antibodies, in Participants With Advanced Solid Tumors

Study Type: INTERVENTIONAL

Last Updated: 2025-11-13

Start Date: 2025-11-04

Completion: 2028-01-31

Conditions

Non-Small Cell Lung Cancer Colorectal Cancer Breast Cancer Ovarian Cancer Endometrial Carcinoma Head and Neck Squamous Cell Carcinoma

Interventions

DRUG

No Results Yet

NCT07214935 | COMPLETED | PHASE1

36 Participants

A TQT Study of Effect of M2951 on Cardiac Repolarization

Study Type: INTERVENTIONAL

Last Updated: 2025-11-13

Start Date: 2022-11-08

Completion: 2023-08-25

Conditions

Healthy

Interventions

DRUG

Results Available

NCT07214727 | RECRUITING | PHASE1

50 Participants

A Study to Evaluate ALN-5288 in Patients With Alzheimer's Disease

Study Type: INTERVENTIONAL

Last Updated: 2025-11-13

Start Date: 2025-10-15

Completion: 2030-03-31

Conditions

Alzheimer's Disease

Interventions

DRUG

No Results Yet

NCT07213661 | RECRUITING | NA

480 Participants

LT Comparative Effectiveness of 2 Caries Treatments

Study Type: INTERVENTIONAL

Last Updated: 2025-11-13

Start Date: 2025-10-08

Completion: 2030-01-31

Conditions

Dental Caries

Interventions

DEVICE

No Results Yet

NCT07209436 | NOT_YET_RECRUITING | NA

212 Participants

Impact of Pectoral Versus Paravertebral Blocks on Pain and Physical Well-Being in Implant-Based Breast Reconstruction

Study Type: INTERVENTIONAL

Last Updated: 2025-11-13

Start Date: 2025-12-01

Completion: 2027-06-30

Conditions

Breast Reconstruction

Interventions

PROCEDURE

No Results Yet

NCT07195695 | NOT_YET_RECRUITING | PHASE3

400 Participants

Beamion LUNG-3: A Study to Test Whether Zongertinib Helps People With Surgically Removed, Non-small Cell Lung Cancer With HER2 Mutations Compared With Standard Treatment

Study Type: INTERVENTIONAL

Last Updated: 2025-11-13

Start Date: 2025-12-05

Completion: 2032-02-26

Conditions

Non-small Cell Lung Cancer

Interventions

DRUG

No Results Yet

NCT07184996 | RECRUITING | PHASE3

980 Participants

An Induction Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Ulcerative Colitis

Study Type: INTERVENTIONAL

Last Updated: 2025-11-13

Start Date: 2025-10-08

Completion: 2028-05-09

Conditions

Ulcerative Colitis

Interventions

DRUG

No Results Yet

NCT07184983 | RECRUITING | NA

46 Participants

RS-tDCS for Cannabis Use Disorder: The C.A.R.E.S. Initiative

Study Type: INTERVENTIONAL

Last Updated: 2025-11-13

Start Date: 2025-11-12

Completion: 2026-10-01

Conditions

Cannabis Use Disorder

Interventions

DEVICE BEHAVIORAL

No Results Yet

NCT07181837 | RECRUITING | PHASE1/PHASE2

12 Participants

A Phase 1/2 Study of the Safety and Efficacy of MVX-220 in Angelman Syndrome

Study Type: INTERVENTIONAL

Last Updated: 2025-11-13

Start Date: 2025-10-29

Completion: 2028-03-31

Conditions

Angelman Syndrome

Interventions

GENETIC

No Results Yet

NCT07178509 | RECRUITING

50 Participants

A Study of SCAD Using Stress Contrast Echocardiography

Study Type: OBSERVATIONAL

Last Updated: 2025-11-13

Start Date: 2025-12-31

Completion: 2027-09-30

Conditions

Spontaneous Coronary Artery Dissection

Interventions

PROCEDURE

No Results Yet

NCT07174349 | RECRUITING | PHASE4

20 Participants

Uroselective Alpha-1-Antagonist to Reduce the Incidence and Duration of Postoperative Urinary Retention Following Spine Surgery

Study Type: INTERVENTIONAL

Last Updated: 2025-11-13

Start Date: 2025-12-01

Completion: 2027-12-31

Conditions

Urinary Retention Postoperative

Interventions

DRUG OTHER

No Results Yet

NCT07168902 | RECRUITING | PHASE2

228 Participants

Phase 2 Study of BL1107 Eye Drops vs. Timolol in Adults With Primary Open Angle Glaucoma or Ocular Hypertension

Study Type: INTERVENTIONAL

Last Updated: 2025-11-13

Start Date: 2025-10-24

Completion: 2026-05-31

Conditions

Glaucoma

Interventions

DRUG

No Results Yet

NCT07162272 | COMPLETED | PHASE4

52 Participants

The Efficacy of Melatonin Patches on Dental Anxiety in Children

Study Type: INTERVENTIONAL

Last Updated: 2025-11-13

Start Date: 2025-06-25

Completion: 2025-08-28

Conditions

Dental Anxiety Children

Interventions

DRUG OTHER

No Results Yet

NCT07161583 | RECRUITING

1000 Participants

Advanta VXT and Flixene PMCF Registry

Study Type: OBSERVATIONAL

Last Updated: 2025-11-13

Start Date: 2025-09-25

Completion: 2026-07-31

Conditions

Peripheral Arterial Disease

Interventions

DEVICE

No Results Yet

NCT07160244 | RECRUITING | PHASE3

6000 Participants

BEATRIX: A Study to Learn About a Group B Streptococcus Vaccine in Healthy Pregnant Women and Their Babies

Study Type: INTERVENTIONAL

Last Updated: 2025-11-13

Start Date: 2025-08-25

Completion: 2028-11-06

Conditions

Healthy

Interventions

BIOLOGICAL

No Results Yet

NCT07159828 | RECRUITING | PHASE1

52 Participants

A Study to Assess AXN-2510 Treatment in Adult Patients With Advanced Solid Tumors

Study Type: INTERVENTIONAL

Last Updated: 2025-11-13

Start Date: 2025-09-15

Completion: 2026-07-31

Conditions

Solid Tumor, Adult

Interventions

BIOLOGICAL

No Results Yet

NCT07158164 | RECRUITING | PHASE4

100 Participants

DPYD Pharmacogenomics and Fluoropyrimidine (FP) Dose-Adjustment

Study Type: INTERVENTIONAL

Last Updated: 2025-11-13

Start Date: 2025-08-27

Completion: 2027-07-07

Conditions

Colorectal Neoplasms Breast Neoplasms Head and Neck Neoplasms Gastro-Intestinal Intraepithelial Neoplasia

Interventions

DRUG

No Results Yet

NCT07156578 | ENROLLING_BY_INVITATION | PHASE2

25 Participants

A Long-Term Study of Bivamelagon in Participants With Hypothalamic Obesity (HO)

Study Type: INTERVENTIONAL

Last Updated: 2025-11-13

Start Date: 2025-11-10

Completion: 2028-04-15

Conditions

Hypothalamic Obesity

Interventions

DRUG

No Results Yet

NCT07154745 | NOT_YET_RECRUITING | PHASE3

35 Participants

A Study to Evaluate How Pozelimab + Cemdisiran Combination Therapy Works in Adult Patients With Paroxysmal Nocturnal Hemoglobinuria (PNH) Whose Current Treatment is Not Working Efficiently

Study Type: INTERVENTIONAL

Last Updated: 2025-11-13

Start Date: 2025-12-19

Completion: 2029-07-27

Conditions

Paroxysmal Nocturnal Hemoglobinuria

Interventions

DRUG

No Results Yet

NCT07150221 | ENROLLING_BY_INVITATION

52 Participants

MDR Vivacit-E Elevated Study

Study Type: OBSERVATIONAL

Last Updated: 2025-11-13

Start Date: 2025-10-10

Completion: 2027-12-31

Conditions

Osteoarthritis (OA) of the Hip Avascular Necrosis of Bone of Hip Protrusio Acetabuli Traumatic Arthropathy-Hip Slipped Capital Femoral Epiphyses Fused Hip Fracture of Pelvis Diastrophic Variant

Interventions

DEVICE

No Results Yet

NCT07148843 | NOT_YET_RECRUITING | PHASE2/PHASE3

105 Participants

Cannabidiol as an Adjunct Treatment for Alcohol Withdrawal and Craving

Study Type: INTERVENTIONAL

Last Updated: 2025-11-13

Start Date: 2026-01-15

Completion: 2030-10-31

Conditions

Alcohol Use Disorder (AUD) Withdrawal From Addictive Substance; Detoxification Craving

Interventions

DRUG

No Results Yet

NCT07147192 | NOT_YET_RECRUITING | NA

85 Participants

Feasibility Study of an Accommodating IOL Design

Study Type: INTERVENTIONAL

Last Updated: 2025-11-13

Start Date: 2025-12-31

Completion: 2027-01-31

Conditions

Aphakia

Interventions

DEVICE PROCEDURE

No Results Yet

NCT07146763 | NOT_YET_RECRUITING | NA

200 Participants

A Trial to Reduce Inappropriate Prescribing to Older Adults Visiting the Emergency Department

Study Type: INTERVENTIONAL

Last Updated: 2025-11-13

Start Date: 2025-11-18

Completion: 2027-03-31

Conditions

Inappropriate Prescribing

Interventions

BEHAVIORAL

No Results Yet

NCT07146750 | RECRUITING | PHASE1

212 Participants

A Bioequivalence Study of Amlitelimab Delivered by 2 Different Devices in Healthy Adult Participants

Study Type: INTERVENTIONAL

Last Updated: 2025-11-13

Start Date: 2025-08-25

Completion: 2026-03-25

Conditions

Healthy Volunteers

Interventions

COMBINATION_PRODUCT

No Results Yet

NCT07136467 | RECRUITING

2795 Participants

A Real World Study to Globally Assess Disease Burden in Adolescent and Adult Participants With Alopecia Areata, Vitiligo, or Hidradenitis Suppurativa

Study Type: OBSERVATIONAL

Last Updated: 2025-11-13

Start Date: 2025-09-02

Completion: 2027-04-30

Conditions

Non-Segmental Vitiligo (NSV) Alopecia Areata Hidradenitis Suppurativa

No Results Yet

NCT07136012 | RECRUITING | PHASE3

11000 Participants

OCEAN(a)-PreEvent - Olpasiran Trials of Cardiovascular Events And LipoproteiN(a) Reduction to Prevent First Major Cardiovascular Events

Study Type: INTERVENTIONAL

Last Updated: 2025-11-13

Start Date: 2025-08-22

Completion: 2031-10-20

Conditions

Cardiovascular Disease

Interventions

DRUG

No Results Yet

NCT07124702 | RECRUITING | NA

45 Participants

Cessation of Dual Use of Cigarettes and E-cigarettes During Pregnancy

Study Type: INTERVENTIONAL

Last Updated: 2025-11-13

Start Date: 2025-10-01

Completion: 2026-09-30

Conditions

Dual Use of Cigarettes and E-cigarettes Gestational Weight Gain Birth-weight-for-gestational-age z Score

Interventions

BEHAVIORAL

No Results Yet

NCT07123961 | RECRUITING | PHASE2

160 Participants

Pediatric Acute Respiratory Distress Syndrome (ARDS) Management Trial

Study Type: INTERVENTIONAL

Last Updated: 2025-11-13

Start Date: 2025-11-07

Completion: 2029-12-31

Conditions

Acute Respiratory Distress Syndrome (ARDS) Ventilator Management Lung-protective Ventilation Pediatric Acute Respiratory Distress Syndrome (PARDS)

Interventions

OTHER

No Results Yet

NCT07115563 | RECRUITING | NA

30 Participants

Daily Amino Acid Supplementation for People With Parkinson's Disease

Study Type: INTERVENTIONAL

Last Updated: 2025-11-13

Start Date: 2025-10-31

Completion: 2027-09-30

Conditions

Parkinson Disease (PD)

Interventions

DIETARY_SUPPLEMENT

No Results Yet