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Clinical Trials

Showing trials with last updates posted in 2025.

NCT07214961 | RECRUITING | PHASE1
80 Participants

Study of Alpha Radioligand Therapy AB001 in Patients With Metastatic Castration Resistant Prostate Cancer (mCRPC)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-11-03
Completion: 2027-11-03
Conditions
Prostate Cancer (CRPC) Metastatic Castrate Resistant Prostate Cancer (mCRPC)
Interventions
DRUG
No Results Yet
NCT07213947 | NOT_YET_RECRUITING | NA
4000 Participants

Comparison of Demand and Substitution for Nicotine Pouches as a Function of Nicotine Dosage

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-11-30
Completion: 2025-12-31
Conditions
Tobacco Use Nicotine Pouch Self-Administration
Interventions
OTHER
No Results Yet
NCT07213804 | RECRUITING | PHASE3
1080 Participants

A Two-Part Phase 3 Study of LY4170156 in Participants With Platinum-Resistant (Part A) and Platinum-Sensitive (Part B) Ovarian Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-10-22
Completion: 2028-04-30
Conditions
Ovarian Neoplasms Fallopian Tube Neoplasms Peritoneal Neoplasms Neoplasm Metastasis
Interventions
DRUG
No Results Yet
NCT07212868 | NOT_YET_RECRUITING | PHASE1
150 Participants

The Role of Glucagon in Glucose Metabolism in Humans With and Without Bariatric Surgery

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-12-01
Completion: 2030-05-01
Conditions
Non-Diabetic
Interventions
DRUG OTHER
No Results Yet
NCT07210086 | NOT_YET_RECRUITING | PHASE2
50 Participants

Phase II Non-Randomized Study Evaluating POSLUMA-PSMA PET Response After Oligo- Metastatic/Progressive-directed Treatment With Radiotherapy (PROMPT-R)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-12-11
Completion: 2027-07-07
Conditions
Prostate Cancer
Interventions
DRUG OTHER
No Results Yet
NCT07206550 | NOT_YET_RECRUITING | NA
3000 Participants

The Role of Framing and Choice Architecture in Patients' Reactions and EHR Error Discovery and Reporting

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-11-30
Completion: 2025-11-30
Conditions
Electronic Health Records
Interventions
BEHAVIORAL
No Results Yet
NCT07205120 | RECRUITING | NA
50 Participants

Fluid Guided Heart Failure Treatment at the Cleveland Clinic

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-10-08
Completion: 2026-03-31
Conditions
Heart Failure
Interventions
DEVICE
No Results Yet
NCT07204444 | COMPLETED | NA
671 Participants

The BE WITH Project: A Partially Nested Randomized Control Trial (PN-RCT)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2021-06-01
Completion: 2024-10-25
Conditions
Older Adults Mental Health Depression Loneliness Social Isolation Suicide Ideations Social Functioning Quality of Life Thwarted Belongingness Perceived Burdensomeness Help-Seeking Behavior Suicide Risk
Interventions
BEHAVIORAL
Results Available
NCT07204080 | NOT_YET_RECRUITING | PHASE2
5 Participants

(TNX-1500) in Kidney Transplant Recipients

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2026-01-01
Completion: 2028-03-01
Conditions
Kidney Transplant Kidney Transplant Failure and Rejection Immunosuppression Immunosuppression After Kidney Transplantation
Interventions
DRUG PROCEDURE
No Results Yet
NCT07202988 | NOT_YET_RECRUITING | NA
80 Participants

Tasting Plant Forward Meals

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2026-01-31
Completion: 2026-12-31
Conditions
Dietary Exposure
Interventions
OTHER
No Results Yet
NCT07201922 | NOT_YET_RECRUITING | PHASE3
80 Participants

A Study to Test Whether Nerandomilast Can Help Slow Down Changes in the Lung in People With a Family History of Pulmonary Fibrosis

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2026-01-23
Completion: 2029-05-14
Conditions
Familial Pulmonary Fibrosis Interstitial Lung Abnormalities Interstitial Lung Diseases
Interventions
DRUG
No Results Yet
NCT07197723 | RECRUITING
150 Participants

Study of How People Make Decisions About Prostate Cancer Risk

Study Type: OBSERVATIONAL
Last Updated: 2025-11-12
Start Date: 2025-09-25
Completion: 2027-09-30
Conditions
High Risk Prostate Cancer
Interventions
GENETIC OTHER
No Results Yet
NCT07197216 | ENROLLING_BY_INVITATION | NA
100 Participants

Evaluation of the Tap Trust Intervention on Water Security Experiences and Beverage Intake

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-11-07
Completion: 2027-07-31
Conditions
Beverage Intake Child Health and Nutrition
Interventions
BEHAVIORAL
No Results Yet
NCT07193511 | RECRUITING | PHASE1/PHASE2
355 Participants

Study of AVZO-103 as a Single Agent and in Combination Therapy in Patients With Locally Advanced or Metastatic Urothelial Cancer or Other Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-10-02
Completion: 2030-03-31
Conditions
Solid Tumor Cancer Locally Advanced Metastatic Solid Tumors Urothelial Cancer
Interventions
DRUG
No Results Yet
NCT07192055 | RECRUITING | NA
572 Participants

Self-sampling to Optimize Anal Lesion Outcomes

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-11-30
Completion: 2028-03-31
Conditions
Anal Cancer
Interventions
BEHAVIORAL OTHER
No Results Yet
NCT07190807 | RECRUITING | NA
70 Participants

Managing Pain Using Optimized Sequences by Adjusting Parameters With Independent Current Control

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-11-07
Completion: 2027-11-30
Conditions
Chronic Pain Intractable Pain Low Back Pain Chronic Low-back Pain Chronic Leg Pain Leg Pain
Interventions
DEVICE
No Results Yet
NCT07190196 | RECRUITING | PHASE3
124 Participants

A 52-week Study of Rilzabrutinib Efficacy and Safety Compared to Placebo in Adults Diagnosed With IgG4-related Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-09-26
Completion: 2028-06-28
Conditions
Immunoglobulin G4 Related Disease
Interventions
DRUG
No Results Yet
NCT07186101 | NOT_YET_RECRUITING | PHASE2
252 Participants

LY4268989 (MORF-057) Co-Administered With Mirikizumab in Adults With Moderately to Severely Active Ulcerative Colitis:

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-11-30
Completion: 2027-05-31
Conditions
Ulcerative Colitis
Interventions
DRUG
No Results Yet
NCT07179614 | NOT_YET_RECRUITING | NA
300 Participants

Kentucky Women's Justice Community Overdose Innovation Network - Phase II

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2026-02-28
Completion: 2030-10-31
Conditions
Overdose Risk Opioid Use Disorder Stimulant Use Disorders
Interventions
BEHAVIORAL
No Results Yet
NCT07178704 | RECRUITING
110 Participants

The Metabolic and Genetic Drivers of Body Composition Changes Following Weight Loss Surgery

Study Type: OBSERVATIONAL
Last Updated: 2025-11-12
Start Date: 2025-11-04
Completion: 2027-02-28
Conditions
Bariatric Surgery Patients
No Results Yet
NCT07166094 | NOT_YET_RECRUITING | PHASE3
544 Participants

Study to Assess the Efficacy and Safety of Rina-S Compared to Treatment of Investigator's Choice in Participants With Endometrial Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-11-21
Completion: 2028-11-30
Conditions
Endometrial Cancer Recurrent or Progressive Endometrial Cancer
Interventions
DRUG
No Results Yet
NCT07164313 | RECRUITING | PHASE1
100 Participants

A Study of ZW251 in Participants With Advanced Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-10-21
Completion: 2027-09-30
Conditions
Hepatocellular Carcinoma
Interventions
DRUG
No Results Yet
NCT07158333 | COMPLETED
15 Participants

Mobile Cardiac Telemetry (MCT) Study

Study Type: OBSERVATIONAL
Last Updated: 2025-11-12
Start Date: 2025-08-05
Completion: 2025-09-12
Conditions
Healthy
Interventions
DEVICE
No Results Yet
NCT07158021 | RECRUITING | PHASE2
75 Participants

Leuprolide and Goserelin for Ovarian Function Suppression in Pre- or Peri-menopausal Women With Breast Cancer, OFS Trial

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-12-01
Completion: 2027-12-01
Conditions
Anatomic Stage I Breast Cancer AJCC v8 Anatomic Stage II Breast Cancer AJCC v8 Anatomic Stage III Breast Cancer AJCC v8 Anatomic Stage IV Breast Cancer AJCC v8 Metastatic Breast Carcinoma
Interventions
PROCEDURE OTHER DRUG
No Results Yet
NCT07157787 | RECRUITING | PHASE2
30 Participants

Study of ALXN1920 in Adult Participants With Primary Membranous Nephropathy (PMN)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-09-19
Completion: 2027-02-12
Conditions
Primary Membranous Nephropathy
Interventions
DRUG
No Results Yet
NCT07157254 | RECRUITING | PHASE2
60 Participants

A Safety and Efficacy Study of GTX-102 in Subjects With Deletion- or Nondeletion-type Angelman Syndrome (AS)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-10-13
Completion: 2030-01-31
Conditions
Angelman Syndrome
Interventions
OTHER DRUG
No Results Yet
NCT07156175 | RECRUITING | PHASE2
54 Participants

A Study to Investigate the Efficacy and Safety of SAR444336 in Adults With Microscopic Colitis in Clinical Remission

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-10-14
Completion: 2027-04-08
Conditions
Microscopic Colitis
Interventions
DRUG
No Results Yet
NCT07155317 | RECRUITING | PHASE2
99 Participants

Time-of-Day Specified Immunotherapy for Advanced Melanoma, The TIME Trial

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-10-29
Completion: 2026-12-31
Conditions
Advanced Acral Melanoma Advanced Cutaneous Melanoma Advanced Mucosal Melanoma Clinical Stage IV Cutaneous Melanoma AJCC v8 Metastatic Acral Melanoma Metastatic Cutaneous Melanoma Metastatic Mucosal Melanoma Unresectable Acral Melanoma Unresectable Cutaneous Melanoma Unresectable Mucosal Melanoma
Interventions
PROCEDURE BIOLOGICAL OTHER
No Results Yet
NCT07155174 | NOT_YET_RECRUITING | PHASE2/PHASE3
180 Participants

A Study to Evaluate the Optimal Dose, Adverse Events and Change in Disease Activity of Intravenous ABBV-706 in Combination With Atezolizumab Versus Standard of Care as First-Line Treatment in Adult Participants With Previously Untreated Extensive Stage Small Cell Lung Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-12-06
Completion: 2029-05-31
Conditions
Small Cell Lung Cancer
Interventions
DRUG
No Results Yet
NCT07154511 | RECRUITING | PHASE1/PHASE2
45 Participants

Phase 2 Trial of Tributyrin in People With Parkinson's Disease and Cognitive Impairments

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-11-07
Completion: 2027-05-31
Conditions
Parkinson Disease Parkinson Disease Dementia
Interventions
DRUG
No Results Yet
NCT07153003 | NOT_YET_RECRUITING | PHASE4
560 Participants

Efficacy And Safety Of Tramadol And Oxycodone Versus Oxycodone Monotherapy For Pain Control After Primary Total Knee And Total Hip Arthroplasty

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-12-01
Completion: 2030-09-01
Conditions
Post Operative Pain
Interventions
DRUG
No Results Yet
NCT07152249 | RECRUITING | NA
13120 Participants

Advancing Strategies to Optimize the PerIopeRativE Management of PostOperative Nausea and Vomiting (ASPIRE-PONV) Trial

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-09-03
Completion: 2026-09-30
Conditions
Postoperative Nausea Postoperative Vomiting
Interventions
OTHER
No Results Yet
NCT07148713 | RECRUITING | NA
60 Participants

Pilot of Continuous Glucose Monitor-Augmented Food Is Medicine

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-09-19
Completion: 2026-06-30
Conditions
Nutrition Type 2 Diabetes T2DM T2DM (Type 2 Diabetes Mellitus) Diabetes Education Diabetes Type 2 Diabetes Mellitis
Interventions
BEHAVIORAL
No Results Yet
NCT07146646 | RECRUITING | PHASE2
27 Participants

Trifluridine/Tipiracil + Oxaliplatin in Participants With Advanced or Metastatic Biliary Tract Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-12-31
Completion: 2027-02-28
Conditions
Biliary Tract Cancer Biliary Tract Neoplasms Cholangiocarcinoma Gallbladder Cancer Gallbladder Carcinoma
Interventions
DRUG
No Results Yet
NCT07145918 | RECRUITING | PHASE2
258 Participants

A Study to Assess Adverse Events, Change in Disease Activity, and How Oral Emraclidine Moves Through the Body in Adult Participants With Schizophrenia

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-08-04
Completion: 2028-02-29
Conditions
Schizophrenia
Interventions
DRUG
No Results Yet
NCT07144826 | NOT_YET_RECRUITING | EARLY_PHASE1
161 Participants

Effects of a Probiotic Intervention on the Gut and Vaginal Microbiome in Patients With Advanced or Recurrent Ovarian Cancer Undergoing Treatment With Platinum Chemotherapy

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2026-01-09
Completion: 2027-07-09
Conditions
Advanced Ovarian Carcinoma Recurrent Ovarian Carcinoma Stage II Ovarian Cancer AJCC v8 Stage III Ovarian Cancer AJCC v8 Stage IV Ovarian Cancer AJCC v8
Interventions
PROCEDURE DRUG DIETARY_SUPPLEMENT OTHER
No Results Yet
NCT07144631 | RECRUITING | NA
15 Participants

Peroneal Electrical Nerve Stimulation in Pregnancy for Restless Legs Syndrome

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-10-15
Completion: 2026-09-30
Conditions
Restless Leg Disorder Restless Leg Syndrome (RLS) Pregnancy Sleep Disorder (Disorder)
Interventions
DEVICE
No Results Yet
NCT07142811 | RECRUITING | PHASE2
100 Participants

A Study to Evaluate Tobevibart+Elebsiran Versus Bulevirtide in Chronic HDV Infection

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-08-05
Completion: 2026-11-30
Conditions
Viral Hepatitis
Interventions
DRUG
No Results Yet
NCT07142343 | RECRUITING | PHASE4
5 Participants

A Study to Test the Safety of Pozelimab in Pediatric Participants 1 to 5 Years of Age With a Rare Disease Called CHAPLE (Complement Hyperactivation, Angiopathic Thrombosis, Protein-losing Enteropathy) Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-12-23
Completion: 2029-08-24
Conditions
CHAPLE Disease
Interventions
DRUG
No Results Yet
NCT07128901 | NOT_YET_RECRUITING | NA
6 Participants

Lower-Limb Exoskeleton Technology for Non-Ambulatory Individuals With Spinal Cord Injury

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2026-01-01
Completion: 2026-12-01
Conditions
Spinal Cord Injuries
Interventions
DEVICE
No Results Yet
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