Fluid Guided Heart Failure Treatment at the Cleveland Clinic

NCT ID: NCT07205120

Last Updated: 2025-11-12

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

50 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-10-08

Study Completion Date

2026-03-31

Brief Summary

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FIGHT-HF is an exploratory non-randomized open-label study evaluating a heart failure management intervention.

The goal of this pilot is to assess the performance of a fluid-guided heart failure management program and Alert Response Guide (ARG) using the Bodyport Cardiac Scale and Congestion Index in 50 adult participants with acute and chronic heart failure, who are followed by a Cleveland Clinic cardiologist.

Detailed Description

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This study will assess the clinical integration of the Cardiac Scale and a composite biomarker algorithm, the Congestion Index and Alert, into existing health system workflows for HF management. The data collected in this study will be used to test and refine existing Congestion Index-guided HF management protocols contained within an Alert Response Guide (ARG). The final Alert Response Guide may be further validated in future randomized control trials.

Conditions

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Heart Failure

Keywords

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scale

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Interventional arm

Participants will begin receiving fluid-guided care when they begin using the device in the outpatient (home) setting.

Participants will be monitored per routine clinical care and receive study follow-up visits at 45- and 90-days to assess clinical status, events, and medication changes.

Group Type EXPERIMENTAL

Heart Failure Management Intervention

Intervention Type DEVICE

Participants will receive access to their weight and fluid levels on the Cardiac Scale and through the Bodyport Patient Portal. The provider will receive access to the Congestion Index, alerts, and Clinical Dashboard to support the remote management of the participant. The provider will receive a notice when an alert is generated and twice weekly reminders until the Congestion Index returns below an alert threshold. When an alert is generated, providers will attempt to contact the participant and will be encouraged to follow the recommendations contained within the ARG. Providers will also be encouraged to provide feedback and suggest improvements to the ARG throughout the study. Any changes to medical therapy resulting from an alert will be documented in the Bodyport Clinical Dashboard.

Interventions

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Heart Failure Management Intervention

Participants will receive access to their weight and fluid levels on the Cardiac Scale and through the Bodyport Patient Portal. The provider will receive access to the Congestion Index, alerts, and Clinical Dashboard to support the remote management of the participant. The provider will receive a notice when an alert is generated and twice weekly reminders until the Congestion Index returns below an alert threshold. When an alert is generated, providers will attempt to contact the participant and will be encouraged to follow the recommendations contained within the ARG. Providers will also be encouraged to provide feedback and suggest improvements to the ARG throughout the study. Any changes to medical therapy resulting from an alert will be documented in the Bodyport Clinical Dashboard.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Hospitalized for acute decompensated heart failure
* Age 21 years or older
* Able to speak and read English

Exclusion Criteria

* New York Heart Association functional class IV symptoms
* Received or are scheduled to receive a heart transplant or ventricular assist - device in the next 12 months
* Have a glomerular filtration rate of less than 25 mL/min while nonresponsive to diuretic therapy or on chronic renal dialysis
* Have a history of regularly scheduled intravenous HF therapy (e.g., inotropes or diuretics)
* Have a life expectancy of less than 12 months
* Are pregnant or plan to become pregnant during the next 12 months
* Weigh greater than 375 lbs
* Unable to stand on two bare feet without assistance
Minimum Eligible Age

21 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Bodyport Inc.

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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The Cleveland Clinic

Cleveland, Ohio, United States

Site Status RECRUITING

Countries

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United States

Facility Contacts

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Elaine Franko

Role: primary

Other Identifiers

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25-529

Identifier Type: -

Identifier Source: org_study_id