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Clinical Trials

Showing trials with last updates posted in 2025.

NCT06254326 | ACTIVE_NOT_RECRUITING | PHASE1
12 Participants

ADAGiO: Adoptive Cellular Therapy for the TreAtment of Recurrent OliGodendrogliOma (OG) Adult Patients

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-09-19
Completion: 2027-12-31
Conditions
Recurrent Oligodendroglioma Progressive Oligodendroglioma
Interventions
BIOLOGICAL DRUG
No Results Yet
NCT06246110 | RECRUITING | PHASE2
70 Participants

A Phase 2 Study of EIK1001 in Combo With Pembrolizumab and Chemotherapy in Patients With Stage 4 NSCLC

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-02-06
Completion: 2026-12-31
Conditions
NSCLC
Interventions
DRUG
No Results Yet
NCT06227026 | RECRUITING | PHASE1
10 Participants

Pilot Study of Anti-CD19 Chimeric Antigen Receptor T Cells (CAR-T Cells) for the Treatment of Relapsed/Refractory CD19+ Malignancies

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-02-20
Completion: 2026-01-15
Conditions
Acute Lymphoblastic Leukemia Diffuse Large B Cell Lymphoma
Interventions
BIOLOGICAL
No Results Yet
NCT06226805 | RECRUITING | PHASE2
156 Participants

Study of BB-031 in Acute Ischemic Stroke Patients (RAISE)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-07-31
Completion: 2027-06-30
Conditions
Acute Ischemic Stroke
Interventions
DRUG
No Results Yet
NCT06223555 | RECRUITING | NA
79 Participants

Variability In Mixed Meal Tests: Fixed Versus Adjusted to Energy Needs Caloric Dose

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-08-23
Completion: 2026-06-30
Conditions
Obesity Healthy Volunteer
Interventions
OTHER
No Results Yet
NCT06215118 | RECRUITING | PHASE1
87 Participants

A Study to Learn About the Effects of the Combination of Elranatamab (PF-06863135) and Iberdomide in Patients With Relapsed or Refractory Multiple Myeloma (MagnetisMM-30)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-02-20
Completion: 2027-04-10
Conditions
Multiple Myeloma
Interventions
DRUG
No Results Yet
NCT06214741 | ACTIVE_NOT_RECRUITING | PHASE3
307 Participants

A Study to Test Whether Survodutide (BI 456906) Helps Chinese People Living With Overweight or Obesity to Lose Weight

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-02-06
Completion: 2025-07-29
Conditions
Obesity Overweight
Interventions
DRUG
No Results Yet
NCT06212752 | ACTIVE_NOT_RECRUITING | PHASE3
39 Participants

A Study of Subcutaneous (SC) Pembrolizumab Coformulated With Berahyaluronidase Alfa (MK-3475A) vs Intravenous Pembrolizumab in Adult Participants With Metastatic Non-small Cell Lung Cancer (NSCLC) (MK-3475A-D77)-Japan Extension

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2023-06-13
Completion: 2024-11-06
Conditions
Metastatic Non-small Cell Lung Cancer
Interventions
BIOLOGICAL DRUG
Results Available
NCT06206746 | RECRUITING | NA
195 Participants

The REBALANCE Study - a Prospective, Multicenter, Randomized, Pivotal Study of the May Health System

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-03-25
Completion: 2026-06-30
Conditions
Polycystic Ovary Syndrome Infertility, Female
Interventions
DEVICE
No Results Yet
NCT06195306 | RECRUITING | PHASE2
66 Participants

Low Dose Tamoxifen With or Without Omega-3 Fatty Acids for Breast Cancer Risk Reduction

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-04-01
Completion: 2027-10-01
Conditions
Breast Atypical Hyperplasia Breast Carcinoma Breast Ductal Carcinoma In Situ Breast Lobular Carcinoma In Situ
Interventions
PROCEDURE DRUG OTHER
No Results Yet
NCT06192160 | RECRUITING | PHASE2
315 Participants

Trial of Novel Regimens for the Treatment of Pulmonary Tuberculosis

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-03-11
Completion: 2026-11-11
Conditions
Pulmonary Tuberculosis
Interventions
DRUG
No Results Yet
NCT06191484 | RECRUITING | NA
169 Participants

Risk and Resilience to Suicide Following Late-Life Spousal Bereavement

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2023-11-20
Completion: 2028-12-31
Conditions
Suicide Bereavement
Interventions
BEHAVIORAL
No Results Yet
NCT06189807 | ACTIVE_NOT_RECRUITING | NA
70 Participants

Pregnancy and Contraception Education in Chronic Kidney Disease (PACE-CKD)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-02-14
Completion: 2025-09-24
Conditions
CKD Chronic Kidney Diseases
Interventions
BEHAVIORAL OTHER
No Results Yet
NCT06176365 | ACTIVE_NOT_RECRUITING | PHASE3
274 Participants

A Study to Test Whether Survodutide Helps Japanese People Living With Obesity Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-01-16
Completion: 2025-12-03
Conditions
Obesity
Interventions
DRUG
No Results Yet
NCT06173804 | ACTIVE_NOT_RECRUITING | NA
20 Participants

Multilevel Lifestyle Intervention to Improve Physical Function in Older Adults With Type 2 Diabetes

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-07-22
Completion: 2025-05-23
Conditions
Type 2 Diabetes
Interventions
OTHER
No Results Yet
NCT06164951 | ACTIVE_NOT_RECRUITING | PHASE3
110 Participants

A Study to Evaluate the Efficacy and Safety of Infigratinib in Children and Adolescents With Achondroplasia

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2023-11-10
Completion: 2025-12-31
Conditions
Achondroplasia
Interventions
DRUG
No Results Yet
NCT06152575 | RECRUITING | PHASE3
492 Participants

MagnetisMM-32: A Study to Learn About the Study Medicine Called Elranatamab in People With Multiple Myeloma (MM) That Has Come Back After Taking Other Treatments (Including Prior Treatment With an Anti-CD38 Antibody and Lenalidomide)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-02-08
Completion: 2026-08-30
Conditions
Multiple Myeloma
Interventions
DRUG
No Results Yet
NCT06150417 | RECRUITING | PHASE2
200 Participants

MDRT in Prostate Cancer Treated With Long-term Androgen Deprivation Therapy in the STAMPEDE Trial (METANOVA)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-07-01
Completion: 2028-04-01
Conditions
Prostate Cancer Malignant Neoplasm of Prostate Secondary Malignant Neoplasm of Prostate
Interventions
DRUG OTHER RADIATION
No Results Yet
NCT06139328 | ACTIVE_NOT_RECRUITING | PHASE2
160 Participants

IRI-EXPLORE: A Study to Test Whether BI 765845 Helps People Who Have Had a Heart Attack

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2023-12-05
Completion: 2025-09-02
Conditions
Myocardial Infarction
Interventions
DRUG
No Results Yet
NCT06136624 | RECRUITING | PHASE3
1310 Participants

Study of Opevesostat (MK-5684) Versus Alternative NHA in mCRPC (MK-5684-003)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2023-12-31
Completion: 2028-08-02
Conditions
Prostate Cancer Metastatic
Interventions
DRUG
No Results Yet
NCT06133634 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2
70 Participants

Fisetin to Improve Vascular Function in Older Adults

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2023-09-25
Completion: 2026-03-31
Conditions
Aging Endothelial Dysfunction Arterial Stiffness
Interventions
DIETARY_SUPPLEMENT OTHER
No Results Yet
NCT06132113 | RECRUITING | PHASE1
55 Participants

DAREONโ„ข-7: A Study to Test How Well Different Doses of BI 764532 in Addition to Chemotherapy Are Tolerated by People With Advanced Neuroendocrine Cancers

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-01-22
Completion: 2027-02-09
Conditions
Neuroendocrine Neoplasms
Interventions
DRUG
No Results Yet
NCT06128928 | RECRUITING | NA
900 Participants

Connecting Friends and Health Workers to Boost COVID-19 Vaccination in Latino Communities

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2023-07-08
Completion: 2026-12-31
Conditions
COVID-19 Vaccine
Interventions
BEHAVIORAL
No Results Yet
NCT06127407 | RECRUITING | PHASE3
136 Participants

Ivosidenib in Participants With Locally Advanced or Metastatic Conventional Chondrosarcoma Untreated or Previously Treated With 1 Systemic Treatment Regimen

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-07-09
Completion: 2028-02-01
Conditions
Locally Advanced or Metastatic Conventional Chondrosarcoma With an IDH1 Mutation, Untreated or Previously Treated With 1 Systemic Treatment Regimen
Interventions
DRUG
No Results Yet
NCT06126276 | RECRUITING | PHASE2
70 Participants

Testing the Use of Neratinib or the Combination of Neratinib and Palbociclib Targeted Treatment for HER2+ Solid Tumors (A ComboMATCH Treatment Trial)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-05-07
Completion: 2027-02-20
Conditions
Malignant Female Reproductive System Neoplasm Malignant Solid Neoplasm Recurrent Malignant Female Reproductive System Neoplasm Recurrent Malignant Solid Neoplasm
Interventions
PROCEDURE DRUG
No Results Yet
NCT06123195 | RECRUITING | NA
40 Participants

Effects of Constipation Treatment in Chronic Kidney Disease: A Pilot Feasibility Trial

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-02-01
Completion: 2025-11-17
Conditions
Chronic Kidney Disease Constipation
Interventions
OTHER
No Results Yet
NCT06122935 | COMPLETED | NA
6735 Participants

Evaluation of the Aurora Xi New Nomogram Software 2.0

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2023-11-27
Completion: 2024-04-19
Conditions
Apheresis Related Hypotension
Interventions
DEVICE
Results Available
NCT06121297 | RECRUITING | PHASE1/PHASE2
12 Participants

RESET-SLE: A Phase 1/2 Open-Label Study to Evaluate the Safety and Efficacy of CABA-201 in Subjects With Active Systemic Lupus Erythematosus

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-02-16
Completion: 2027-12-31
Conditions
Systemic Lupus Erythematosus Lupus Nephritis
Interventions
BIOLOGICAL
No Results Yet
NCT06117891 | RECRUITING
300 Participants

An Observational Study to Learn More About How Well a Treatment Works When Given After Treatment With Atezolizumab and Bevacizumab or Another Similar Combination of Drugs in Adults With Liver Cancer That Cannot be Treated With Surgery

Study Type: OBSERVATIONAL
Last Updated: 2025-11-12
Start Date: 2023-11-27
Completion: 2026-11-27
Conditions
Unresectable Hepatocellular Carcinoma
Interventions
DRUG
No Results Yet
NCT06112418 | RECRUITING | NA
7500 Participants

A Randomized Comparison of Stage-Based Care Versus Risk Factor-Based Care for Prevention of Cardiovascular Events

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-03-06
Completion: 2029-03-05
Conditions
Diabetes Mellitus, Type 2 PreDiabetes Metabolic Syndrome
Interventions
DEVICE
No Results Yet
NCT06109181 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2
10 Participants

Gene Therapy for ACM Due to a PKP2 Pathogenic Variant

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-02-29
Completion: 2026-12-31
Conditions
Arrhythmogenic Cardiomyopathy PKP2-ACM PKP2-ARVC
Interventions
GENETIC
No Results Yet
NCT06098079 | RECRUITING | PHASE4
8600 Participants

Effect of Naltrexone Hydrochloride ER and Bupropion Hydrochloride ER Combination (Contraveยฎ/Mysimbaยฎ) on Major Adverse Cardiovascular Events (MACE)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-01-03
Completion: 2029-01-31
Conditions
Obesity
Interventions
DRUG
No Results Yet
NCT06095505 | RECRUITING | PHASE2
80 Participants

A Study of Alisertib in Patients With Extensive Stage Small Cell Lung Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-02-08
Completion: 2027-04-30
Conditions
Small Cell Lung Cancer
Interventions
DRUG
No Results Yet
NCT06087640 | RECRUITING | PHASE3
35800 Participants

A Clinical Study to Evaluate the Efficacy, Safety and Immunogenicity of an Adjuvanted Influenza Vaccine Compared to a Non-adjuvanted Influenza Vaccine in Adults โ‰ฅ65 Years of Age

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2023-10-23
Completion: 2026-11-30
Conditions
Influenza, Human
Interventions
BIOLOGICAL
No Results Yet
NCT06077500 | ACTIVE_NOT_RECRUITING | PHASE1
46 Participants

DAREONแต€แดน-8: A Study to Test How Well Different Doses of BI 764532 in Addition to Standard of Care Are Tolerated by People With Advanced Small Cell Lung Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-02-14
Completion: 2025-12-01
Conditions
Small Cell Lung Carcinoma (SCLC)
Interventions
DRUG
No Results Yet
NCT06074588 | RECRUITING | PHASE3
556 Participants

Sacituzumab Tirumotecan (MK-2870) Versus Chemotherapy in Previously Treated Advanced or Metastatic Nonsquamous Non-small Cell Lung Cancer (NSCLC) With EGFR Mutations or Other Genomic Alterations (MK-2870-004)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2023-11-12
Completion: 2027-05-10
Conditions
Non-small Cell Lung Cancer (NSCLC)
Interventions
BIOLOGICAL DRUG
No Results Yet
NCT06073821 | ACTIVE_NOT_RECRUITING | PHASE3
652 Participants

Study of Sonrotoclax (BGB-11417) Plus Zanubrutinib (BGB-3111) Compared With Venetoclax Plus Obinutuzumab in Participants With Chronic Lymphocytic Leukemia (CLL)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2023-11-11
Completion: 2032-02-29
Conditions
CLL
Interventions
DRUG
No Results Yet
NCT06067347 | RECRUITING
1200 Participants

A Global Study of the PETAL Consortium

Study Type: OBSERVATIONAL
Last Updated: 2025-11-12
Start Date: 2024-01-05
Completion: 2028-01-31
Conditions
T-Cell and NK-Cell Neoplasm
No Results Yet
NCT06064097 | RECRUITING | PHASE2
50 Participants

A Study Using Nivolumab, in Combination With Chemotherapy Drugs to Treat Nasopharyngeal Carcinoma (NPC)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-06-25
Completion: 2026-12-31
Conditions
Stage II Nasopharyngeal Carcinoma AJCC v8 Stage III Nasopharyngeal Carcinoma AJCC v8 Stage IV Nasopharyngeal Carcinoma AJCC v8
Interventions
PROCEDURE DRUG OTHER BIOLOGICAL RADIATION
No Results Yet
NCT06062368 | RECRUITING | NA
100 Participants

Reducing Vertigo Associated With MRI Machines

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-01-15
Completion: 2027-01-01
Conditions
Vertigo Dizziness
Interventions
BEHAVIORAL
No Results Yet
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