Clinical Trials

NCT07091422 | RECRUITING | NA
20 Participants

A Split-Mouth Clinical Trial Evaluating the Bond Failure Rate of a New Etch-Free Orthodontic Adhesive

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-11-05
Completion: 2026-08-11
Conditions
Bracket Bonding Orthodontic Treatment Dental Adhesives/Restorations Performance White Spot Lesion of Tooth
Interventions
DEVICE
No Results Yet
NCT07090226 | RECRUITING | NA
65 Participants

Diffuse Cutaneous Scleroderma (DSSc) SFDI Study

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-11-06
Completion: 2028-12-31
Conditions
Systemic Scleroderma Diffuse Cutaneous Scleroderma
Interventions
OTHER
No Results Yet
NCT07089576 | RECRUITING | NA
132 Participants

Clinical Study to Evaluate the Safety and Effectiveness of Arcevo LSA

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-11-04
Completion: 2028-04-30
Conditions
Aortic Arch Aneurysm Aortic Arch Dissection Chronic Aortic Dissection Acute Aortic Dissection
Interventions
DEVICE
No Results Yet
NCT07082725 | RECRUITING | PHASE3
72 Participants

A Study to Evaluate the Safety and Efficacy of Oral Nizubaglustat (AZ-3102) in Late-infantile and Juvenile Forms of Niemann-Pick Type C Disease (NPC)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-06-30
Completion: 2027-11-04
Conditions
Niemann-Pick Type C Disease
Interventions
DRUG
No Results Yet
NCT07082543 | RECRUITING | PHASE3
75 Participants

A Study to Evaluate the Safety and Efficacy of Oral Nizubaglustat (AZ-3102) in Late-infantile and Juvenile Forms of GM1 Gangliosidosis or GM2 Gangliosidosis

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-06-30
Completion: 2027-11-04
Conditions
Gangliosidoses, GM2 Gangliosidosis, GM1
Interventions
DRUG
No Results Yet
NCT07077746 | RECRUITING | PHASE2
46 Participants

HB-adMSCs for the Treatment of Crohn's Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2026-01-31
Completion: 2027-12-31
Conditions
Crohn Disease (CD)
Interventions
DRUG
No Results Yet
NCT07076186 | NOT_YET_RECRUITING | PHASE2
48 Participants

Phase II Decentralized Pragmatic Trial of Adjuvant Doxorubicin - Trabectedin Chemotherapy in uLMS

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-12-01
Completion: 2027-12-02
Conditions
Uterine Leiomyosarcoma
Interventions
DRUG
No Results Yet
NCT07076160 | COMPLETED | NA
74 Participants

Pilot Dispensing Study of Two Marketed Daily Disposable Multifocal Contact Lenses

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-07-24
Completion: 2025-09-20
Conditions
Visual Acuity Presbyopia
Interventions
DEVICE
No Results Yet
NCT07075588 | NOT_YET_RECRUITING | NA
100 Participants

Integrating Free-choice Marketplace, dieTitian coacHing, cultuRally Tailored messagIng to improVE Blood Pressure

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2026-01-01
Completion: 2026-11-30
Conditions
Hypertension Hypertension Complicated With Type 2 Diabetes
Interventions
BEHAVIORAL
No Results Yet
NCT07066722 | RECRUITING | PHASE1
124 Participants

A Study to Evaluate VH4524184 Tablet Absorption, Effects of Food, and Interactions With Other Drugs in Healthy Adults

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-07-07
Completion: 2025-12-15
Conditions
HIV Infections
Interventions
DRUG
No Results Yet
NCT07061652 | RECRUITING | NA
162 Participants

Expanding the Support of Family Caregivers of Diverse Patients With Cancer and Diabetes

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-07-03
Completion: 2026-06-30
Conditions
Cancer Diabetes
Interventions
BEHAVIORAL OTHER
No Results Yet
NCT07056699 | NOT_YET_RECRUITING | PHASE3
24 Participants

SGLT2i, Pioglitazone, and Ketone Production in T1D

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2026-01-30
Completion: 2027-06-01
Conditions
Type1diabetes
Interventions
DRUG OTHER
No Results Yet
NCT07056361 | RECRUITING | NA
60 Participants

Stimulating Specific Brain Areas (VOP/VIM) With Electricity to Improve Movement and Muscle Control

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2022-12-16
Completion: 2026-12-31
Conditions
Movement Disorders (Incl Parkinsonism) Stroke Traumatic Brain Injury Brain Diseases Parkinson Disease Essential Tremor, Movement Disorders
Interventions
DEVICE
No Results Yet
NCT07056348 | RECRUITING | NA
60 Participants

Long-term Brain Stimulation of the Motor Ventral Thalamus (VOP/VIM) to Improve Motor Function

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2022-05-10
Completion: 2030-12-31
Conditions
Traumatic Brain Injury Stroke Brain Disease Movement Disorders (Incl Parkinsonism) Central Nervous System Disease Essential Tremor, Movement Disorders Essential Tremor of Voice
Interventions
DEVICE
No Results Yet
NCT07056335 | COMPLETED | NA
108 Participants

Physical Activity and Percussive Massage Therapy for Reducing Pain in Older Women

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-01-15
Completion: 2025-10-14
Conditions
Pain, Chronic
Interventions
BEHAVIORAL DEVICE
No Results Yet
NCT07054515 | RECRUITING | PHASE3
147 Participants

A Study to Evaluate the Safety and Efficacy of Oral Nizubaglustat (AZ-3102) in Late-infantile and Juvenile Forms of Niemann-Pick Type C Disease, GM1 Gangliosidosis or GM2 Gangliosidosis

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-06-30
Completion: 2027-11-04
Conditions
Niemann-Pick Type C Disease GM1 Gangliosidosis GM2 Gangliosidosis
Interventions
DRUG
No Results Yet
NCT07054489 | RECRUITING | NA
10 Participants

UPBEAT: Using Polygenic Scores to Guide BB Therapy in HF With Mildly Reduced EF

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-11-30
Completion: 2026-11-30
Conditions
Heart Failure Polygenic Score
Interventions
OTHER
No Results Yet
NCT07053345 | RECRUITING | PHASE4
47 Participants

A Study of Esketamine Nasal Spray in Korean Participants With Treatment-resistant Depression

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-06-09
Completion: 2027-06-25
Conditions
Depressive Disorder, Treatment-Resistant
Interventions
DRUG
No Results Yet
NCT07049926 | RECRUITING | PHASE1/PHASE2
140 Participants

Substudy 03C: A Study of Combination Therapies in Participants With Renal Cell Carcinoma With Recurrent Disease During or After Anti-PD-(L)1 Therapy (MK-3475-03C/KEYMAKER-U03)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-07-20
Completion: 2031-10-26
Conditions
Renal Cell Carcinoma
Interventions
DRUG
No Results Yet
NCT07049575 | RECRUITING | PHASE1
24 Participants

Study to Evaluate the Maximal Use of Ruxolitinib Cream in Adult and Adolescent Participants With Hidradenitis Suppurativa

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-11-15
Completion: 2026-12-09
Conditions
Hidradenitis Suppurativa
Interventions
DRUG
No Results Yet
NCT07049055 | NOT_YET_RECRUITING | PHASE1/PHASE2
144 Participants

A Clinical Trial to Evaluate EDV Nanocell Therapy With Gemcitabine and Nab-paclitaxel in Pancreatic Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-12-31
Completion: 2028-09-30
Conditions
Pancreatic Cancer, Metastatic PDAC - Pancreatic Ductal Adenocarcinoma
Interventions
DRUG
No Results Yet
NCT07048262 | RECRUITING | PHASE2
450 Participants

Dose Range Finding, Efficacy, and Safety Study of Nebulized CSL787 in Adults With Non-cystic Fibrosis Bronchiectasis (NCFB)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-09-03
Completion: 2028-02-28
Conditions
Non-cystic Fibrosis Bronchiectasis
Interventions
BIOLOGICAL DRUG DEVICE
No Results Yet
NCT07047118 | RECRUITING | PHASE2
130 Participants

A Study of JSB462 (Luxdegalutamide) Plus Lutetium (177Lu) Vipivotide Tetraxetan in Patients With Metastatic Castration Resistant Prostate Cancer (mCRPC)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-07-03
Completion: 2028-01-07
Conditions
Prostatic Cancer, Castration-Resistant
Interventions
DRUG
No Results Yet
NCT07042217 | RECRUITING | NA
25 Participants

Transcranial Direct Current Stimulation for Depression

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-07-01
Completion: 2026-09-01
Conditions
Unipolar Depression
Interventions
DEVICE
No Results Yet
NCT07035431 | NOT_YET_RECRUITING | NA
66 Participants

Endo-SPONGE for Treatment of Anastomotic or Hartmann's Stump Leakages in Lower Pelvic Area

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-11-30
Completion: 2028-12-31
Conditions
Anastomotic Leaks Hartmanns Stump Leakage
Interventions
DEVICE
No Results Yet
NCT07023627 | RECRUITING | PHASE2
160 Participants

A Study of INCB123667 in Participants With Platinum-Resistant Ovarian Cancer With Cyclin E1 Overexpression

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-11-15
Completion: 2027-04-27
Conditions
Ovarian Cancer
Interventions
DRUG
No Results Yet
NCT07023614 | RECRUITING | PHASE2
165 Participants

A Trial to Evaluate the Efficacy and Safety of Ninerafaxstat in Patients With Symptomatic Non-obstructive Hypertrophic Cardiomyopathy

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-10-06
Completion: 2026-12-31
Conditions
Non-obstructive Hypertrophic Cardiomyopathy
Interventions
DRUG
No Results Yet
NCT07022418 | NOT_YET_RECRUITING | PHASE2
120 Participants

Formoterol in Diabetes

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2026-01-31
Completion: 2026-12-31
Conditions
Diabetic Nephropathies Diabetic Kidney Disease
Interventions
DRUG
No Results Yet
NCT07018323 | RECRUITING | PHASE2
210 Participants

A Study to Assess the Efficacy, Safety, and Tolerability of IMVT-1402 as Treatment for Adult Participants With Graves' Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-06-19
Completion: 2027-05-31
Conditions
Graves' Disease
Interventions
DRUG
No Results Yet
NCT07016321 | NOT_YET_RECRUITING | PHASE2/PHASE3
600 Participants

Emetine for Viral Outbreaks (a.k.a. EVOLVE Antiviral Initiative)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-12-01
Completion: 2029-03-01
Conditions
Dengue
Interventions
DRUG
No Results Yet
NCT07015905 | RECRUITING | PHASE3
2000 Participants

REGN7508 Versus Apixaban and Enoxaparin for Thromboprophylaxis After Total Knee Arthroplasty in Adults

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-06-25
Completion: 2027-02-20
Conditions
Venous Thromboembolism (VTE)
Interventions
DRUG
No Results Yet
NCT07011706 | RECRUITING | PHASE2
96 Participants

ATI-045 Versus Placebo in Patients With Moderate-to-Severe Atopic Dermatitis

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-05-30
Completion: 2026-08-31
Conditions
Atopic Dermatitis Atopic Dermatitis AD Eczema
Interventions
DRUG
No Results Yet
NCT07003919 | RECRUITING | PHASE3
480 Participants

Safety Study of Viaskinยฎ Peanut Patch in Peanut-Allergic Children 1 Through 3 Years of Age (COMFORT Toddlers)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-06-24
Completion: 2026-11-30
Conditions
Allergy Peanut Allergy
Interventions
COMBINATION_PRODUCT
No Results Yet
NCT06997497 | RECRUITING | PHASE3
477 Participants

A Clinical Study of MK-1084 With Targeted Therapy and Chemotherapy in People With Colorectal Cancer (MK-1084-012/KANDLELIT-012)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-07-16
Completion: 2029-08-27
Conditions
Colon Adenocarcinoma Rectal Adenocarcinoma
Interventions
DRUG BIOLOGICAL
No Results Yet
NCT06997029 | RECRUITING | PHASE1
234 Participants

A Phase 1 Study of BMS-986500 as Monotherapy or Combination Therapy in Advanced Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-08-01
Completion: 2028-12-14
Conditions
Advanced Solid Tumor Advanced Breast Cancer Advanced Ovarian Cancer
Interventions
DRUG
No Results Yet
NCT06995898 | RECRUITING | NA
24000 Participants

The Vanguard Study: Testing a New Way to Screen for Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-06-16
Completion: 2027-12-31
Conditions
Bladder Carcinoma Breast Carcinoma Colorectal Carcinoma Esophageal Carcinoma Gastric Carcinoma Liver Carcinoma Lung Carcinoma Malignant Solid Neoplasm Ovarian Carcinoma Pancreatic Carcinoma Prostate Carcinoma
Interventions
PROCEDURE DEVICE OTHER
No Results Yet
NCT06995053 | RECRUITING | NA
80 Participants

Computed Tomography-Guided Stereotactic Body Radiation Therapy With Intrafraction Motion Monitoring for the Treatment of Localized Prostate Cancer, ILLUSION Trial

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-06-27
Completion: 2035-09-01
Conditions
Localized Prostate Adenocarcinoma Stage I Prostate Cancer AJCC v8 Stage II Prostate Cancer AJCC v8 Stage III Prostate Cancer AJCC v8
Interventions
PROCEDURE RADIATION OTHER
No Results Yet
NCT06989112 | RECRUITING | PHASE3
600 Participants

DESTINY-Endometrial01: A Phase III Study of Trastuzumab Deruxtecan Plus Rilvegostomig or Pembrolizumab as First-Line Treatment of HER2-Expressing (IHC 3+/2+), Mismatch Repair Proficient (pMMR) Endometrial Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-03-27
Completion: 2029-01-19
Conditions
Endometrial Cancer
Interventions
DRUG
No Results Yet
NCT06988202 | NOT_YET_RECRUITING | NA
630 Participants

Comparative Effectiveness of Different Techniques for Repeat Ablation of Atrial Fibrillation

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-11-30
Completion: 2030-01-01
Conditions
Atrial Fibrillation (AF)
Interventions
PROCEDURE
No Results Yet
NCT06985784 | RECRUITING | NA
40 Participants

Virtual Reality Interventions for the Improvement of Depression, Anxiety and Pain in Patients With Head and Neck Cancer and Caregivers

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-06-25
Completion: 2027-11-09
Conditions
Head and Neck Carcinoma
Interventions
OTHER
No Results Yet
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