Pilot Dispensing Study of Two Marketed Daily Disposable Multifocal Contact Lenses

NCT ID: NCT07076160

Last Updated: 2025-11-10

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

74 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-07-24

Study Completion Date

2025-09-20

Brief Summary

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This is a 6-visit, single-masked, multi-site, 2×3 crossover, randomized-controlled, dispensing clinical trial to evaluate visual acuity.

Detailed Description

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Conditions

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Visual Acuity Presbyopia

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Participants

Study Groups

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Test/Control/Control

Eligible subjects will be randomized into the Test/Control/Control sequence.

Group Type EXPERIMENTAL

INFUSE® One Day Multifocal

Intervention Type DEVICE

Test Lens

ACUVUE® OASYS MAX 1-Day Multifocal Contact Lens

Intervention Type DEVICE

Control Lens

Control/Test/Test

Eligible subjects will be randomized into the Control/Test/Test sequence.

Group Type EXPERIMENTAL

INFUSE® One Day Multifocal

Intervention Type DEVICE

Test Lens

ACUVUE® OASYS MAX 1-Day Multifocal Contact Lens

Intervention Type DEVICE

Control Lens

Interventions

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INFUSE® One Day Multifocal

Test Lens

Intervention Type DEVICE

ACUVUE® OASYS MAX 1-Day Multifocal Contact Lens

Control Lens

Intervention Type DEVICE

Eligibility Criteria

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Exclusion Criteria

1. Be currently pregnant or lactating.
2. Have any active or ongoing ocular or systemic allergies that may interfere with contact lens wear.
3. Have been diagnosed with diabetes.
4. Have any active or ongoing systemic disease, autoimmune disease, or use of medication, which may interfere with contact lens wear. This includes, but not be limited to, hyperthyroidism, Sjögren's syndrome, xerophthalmia, acne rosacea, Stevens-Johnson syndrome, and immunosuppressive diseases or any infectious diseases (e.g. hepatitis, tuberculosis).
5. Have any previous, or planned, ocular or intraocular surgery (e.g. radial keratotomy, PRK, LASIK, lid procedures, dacryocystorhinostomy, peripheral iridotomy/iridectomy, cataract surgery, retinal surgery, etc.).
6. Have a history of amblyopia, strabismus or binocular vision abnormality.
7. Use of any of the following medications within 1 week prior to enrollment: oral retinoid, oral tetracyclines, anticholinergics, oral phenothiazines, oral/inhaled corticosteroids. See section 9.1 for further examples.
8. Be currently using any ocular medications with the exception of rewetting drops.
9. Have a history of herpetic keratitis.
10. Have a history of irregular cornea.
11. Have a history of pathological dry eye.
12. Have participated in any contact lens or lens care product clinical trial within 7 days prior to study enrollment.
13. Be an employee (e.g., Investigator, Coordinator, Technician) or immediate family member of an employee (including partner, child, parent, grandparent, grandchild, sibling of the employee or their spouse) of the clinical site.
14. Have any known hypersensitivity or allergic reaction to non-preserved rewetting drop solutions or sodium fluorescein.
15. Have clinically significant (grade 3 or higher on the FDA grading scale) slit lamp findings (e.g., corneal edema, neovascularization or staining, tarsal abnormalities or bulbar injection) or other corneal or ocular disease or abnormalities that contraindicate contact lens wear or may otherwise compromise study endpoints (including entropion, ectropion, chalazia, recurrent styes, glaucoma, history of recurrent corneal erosions, aphakia, moderate or above corneal distortion, herpetic keratitis).
16. Have any current ocular infection or inflammation.
Minimum Eligible Age

40 Years

Maximum Eligible Age

70 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Johnson & Johnson Vision Care, Inc.

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Johnson & Johnson Vision Care, Inc. Clinical Trial

Role: STUDY_DIRECTOR

Johnson & Johnson Vision Care, Inc.

Locations

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Dr. James Weber & Associates, PA - City Square Blvd

Jacksonville, Florida, United States

Site Status

VRC

Jacksonville, Florida, United States

Site Status

Pearson Research Center, PA

Longwood, Florida, United States

Site Status

Maitland Vision Center - North Orlando Ave

Maitland, Florida, United States

Site Status

Sacco Eye Group

Vestal, New York, United States

Site Status

Luxe Vision and Optical

Powell, Ohio, United States

Site Status

Dr. David W. Ferris & Associates

Warwick, Rhode Island, United States

Site Status

Countries

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United States

Other Identifiers

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CR-6612

Identifier Type: -

Identifier Source: org_study_id