A Dispensing Clinical Trial of Comfilcon A Extended Range Multifocal Lenses

NCT ID: NCT02719353

Last Updated: 2020-07-30

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

14 participants

Study Classification

INTERVENTIONAL

Study Start Date

2016-03-31

Study Completion Date

2016-08-31

Brief Summary

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The aim of this study is to validate the clinical of comfilcon A extended range high add center near (CN) multifocal lenses in existing contact lens wearers against the current comfilcon A high add multifocal lenses.

Detailed Description

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This study is a 13-subject, randomized, prospective, single site, daily wear, single-masked (to the subject), bilateral, 4-day cross-over, dispensing study comparing the comfilcon A extended range multifocal test lens against the comfilcon A multifocal control lens.

Conditions

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Presbyopia

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Participants

Study Groups

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comfilcon A Extended Range test lens

Subjects will be randomized to wear either the test or control pair of lens, then cross over to the alternate pair.

Group Type EXPERIMENTAL

comfilcon A Extended Range test lens

Intervention Type DEVICE

contact lens

comfilcon A control lens

Intervention Type DEVICE

contact lens

comfilcon A control lens

Subjects will be randomized to wear either the test or control pair of lens, then cross over to the alternate pair.

Group Type ACTIVE_COMPARATOR

comfilcon A Extended Range test lens

Intervention Type DEVICE

contact lens

comfilcon A control lens

Intervention Type DEVICE

contact lens

Interventions

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comfilcon A Extended Range test lens

contact lens

Intervention Type DEVICE

comfilcon A control lens

contact lens

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

A person is eligible for inclusion in the study if he/she:

* Has had a self-reported oculo-visual examination in the last two years
* Is 50 years of age or greater and has full legal capacity to volunteer
* Is able to read and understand the informed consent
* Is willing and able to follow instructions and maintain the appointment schedule
* Has a spherical distance contact lens prescription between -1.00 and -5.00D (Diopters) (inclusive)
* Near Add Power requirement of +2.25D or greater
* Has spectacle cylinder 0.75 D in both eyes
* Has normal binocularity (no amblyopia, no strabismus, no habitually uncorrected anisometropia ≥ 2.00D)
* Has monocular best-corrected distance visual acuity of 20/30 or better in each eye
* Has clear corneas and no active ocular disease
* Has not worn gas permeable contact lenses for 1 month prior to the study

Exclusion Criteria

A person will be excluded from the study if he/she:

* Has never worn contact lenses before
* Has any systemic disease affecting ocular health
* Is using any systemic or topical medications that will affect ocular health
* Has any ocular pathology or abnormality that would affect the wearing of contact lenses
* Is aphakic (i.e. missing their natural lens inside their eye)
* Has uncorrected anisometropia (i.e. difference in the prescription between the eyes) of ≥2.00 D
* Has undergone corneal refractive surgery
* Is participating in any other type of eye related clinical or research study.
Minimum Eligible Age

50 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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CooperVision, Inc.

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Pete S Kollbaum, O.D.

Role: PRINCIPAL_INVESTIGATOR

Indiana University

Locations

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CORL, Indiana University

Bloomington, Indiana, United States

Site Status

Countries

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United States

Other Identifiers

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CV-16-02

Identifier Type: -

Identifier Source: org_study_id

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