Clinical Evaluation of Investigational Multifocal Toric Contact Lenses

NCT ID: NCT03519282

Last Updated: 2020-05-04

Study Results

Results available

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

13 participants

Study Classification

INTERVENTIONAL

Study Start Date

2018-04-25

Study Completion Date

2018-07-24

Brief Summary

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This non-dispensing study is to evaluate the clinical performance of a test multifocal toric silicone hydrogel contact lens compared to a marketed multifocal toric contact lens (control).

Detailed Description

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This non-dispensing study is to evaluate the clinical performance of a test multifocal toric silicone hydrogel contact lens compared to a marketed multifocal toric contact lens (control).

Conditions

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Presbyopia Astigmatism

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Participants

Study Groups

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Test Multifocal Toric Lens

comfilcon A multifocal toric lens

Group Type EXPERIMENTAL

comfilcon A multifocal toric lens

Intervention Type DEVICE

contact lens

omafilcon A Multifocal Toric Lens

Intervention Type DEVICE

contact lens

omafilcon A Multifocal Toric Lens

Control multifocal toric lens

Group Type ACTIVE_COMPARATOR

comfilcon A multifocal toric lens

Intervention Type DEVICE

contact lens

omafilcon A Multifocal Toric Lens

Intervention Type DEVICE

contact lens

Interventions

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comfilcon A multifocal toric lens

contact lens

Intervention Type DEVICE

omafilcon A Multifocal Toric Lens

contact lens

Intervention Type DEVICE

Other Intervention Names

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Test Multifocal Toric Lens Biofinity multifocal toric lens Proclear multifocal toric lens Control multifocal toric lens

Eligibility Criteria

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Inclusion Criteria

* Has had a self-reported oculo-visual examination in the last two years.
* Is aged 40-75 years, inclusive and has full legal capacity to volunteer.
* Has read and understood the participant information sheet.
* Is willing and able to follow instructions and maintain the appointment schedule.
* Is able to participate in Parts A and B related to this work.
* Has a contact lens spherical prescription between +10.00 to -10.00D (inclusive).
* Has an Add component to their spectacle refraction (between +0.75 and +2.50DS).
* Has astigmatism between -0.75 and -5.75DC (based on the vertexed ocular refraction in each eye.
* Can be satisfactorily fitted with the study lenses.
* Is correctable to a visual acuity of 20/40 (0.30 logMAR) or better (in each eye) with their habitual vision correction or 20/25 (0.10 logMAR) best-corrected.
* They have successfully worn soft contact lenses in the last six months
* Has clear corneas and no active ocular disease.
* Has not worn lenses for at least 12 hours before the examination.
* Has an up-to-date pair of spectacles.

Exclusion Criteria

* Has never worn contact lenses before.
* Has any systemic disease affecting ocular health.
* Is using any systemic or topical medications that will affect ocular health.
* Has any ocular pathology or severe insufficiency of lacrimal secretion (moderate to severe dry eyes) that would, in the opinion of the investigator, affect the wearing of contact lenses.
* Has persistent, clinically significant corneal or conjunctival staining using sodium fluorescein dye that would, in the opinion of the investigator, be problematic for their participation in the study.
* Has any clinically significant lid or conjunctival abnormalities, active neovascularization or any central corneal scars.
* Is aphakic.
* Has undergone corneal refractive surgery.
* Has a history of anaphylaxis or severe allergic reaction.
* Has diabetes or an infectious or immunosuppressive disease which could contraindicate contact lens wear or pose a risk to the investigator.
* They are pregnant or breast-feeding.
* Is participating in any other type of eye-related clinical or research study.
Minimum Eligible Age

40 Years

Maximum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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CooperVision, Inc.

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Philip Morgan, BSc, PhD, MCOptom

Role: PRINCIPAL_INVESTIGATOR

Eurolens Research

Locations

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Eurolens Research

Manchester, , United Kingdom

Site Status

Countries

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United Kingdom

Provided Documents

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Document Type: Study Protocol and Statistical Analysis Plan

View Document

Other Identifiers

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CV-18-11

Identifier Type: -

Identifier Source: org_study_id

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