Fitting Evaluation of Hydrogel and Silicone Hydrogel Spherical Contact Lenses

NCT ID: NCT03235115

Last Updated: 2019-09-12

Study Results

Results available

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

40 participants

Study Classification

INTERVENTIONAL

Study Start Date

2017-06-23

Study Completion Date

2017-09-22

Brief Summary

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This study aims to compare the short-term clinical performance of the three contact lenses (Methafilcon A IV, Ocufilcon B 1-day and Omafilcon A 1-day daily disposable).

Detailed Description

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This will be a randomized, double-masked, crossover, bilateral non-dispensing study, controlled by cross-comparison. Forty subjects will wear each lens brand for approximately one hour, on three separate study days in random order. Lenses will only be worn during study visits.

Conditions

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Myopia

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Investigators

Study Groups

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Methafilcon A IV

Subjects are randomized to wear Methafilcon A IV for 1 hour during the cross over study.

Group Type ACTIVE_COMPARATOR

Ocufilcon B

Intervention Type DEVICE

Contact Lens

Omafilcon A

Intervention Type DEVICE

Contact Lens

Ocufilcon B

Subjects are randomized to wear Ocufilcon B for 1 hour during the cross over study.

Group Type ACTIVE_COMPARATOR

Methafilcon A IV

Intervention Type DEVICE

Contact Lens

Omafilcon A

Intervention Type DEVICE

Contact Lens

Omafilcon A

Subjects are randomized to wear Omafilcon A for 1 hour during the cross over study.

Group Type ACTIVE_COMPARATOR

Methafilcon A IV

Intervention Type DEVICE

Contact Lens

Ocufilcon B

Intervention Type DEVICE

Contact Lens

Interventions

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Methafilcon A IV

Contact Lens

Intervention Type DEVICE

Ocufilcon B

Contact Lens

Intervention Type DEVICE

Omafilcon A

Contact Lens

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* They are of aged 18-40 and have capacity to volunteer.
* They understand their rights as a research subject and are willing and able to sign a Statement of Informed Consent.
* They are willing and able to follow the protocol.
* They agree not to participate in other clinical research for the duration of this study.
* They have a contact lens spherical prescription between -1.00 to - 6.00D (inclusive)
* They have a spectacle cylindrical correction of -0.75D or less in each eye (based on the ocular refraction).
* They can attain at least 0.10 logMAR distance high contrast visual acuity in each eye with the study lenses within the available power range.
* They currently use soft contact lenses or have done so in the previous six months.

Exclusion Criteria

* They have an ocular disorder which would normally contra-indicate contact lens wear.
* They have a systemic disorder which would normally contra-indicate contact lens wear.
* They are using any topical medication such as eye drops or ointment.
* They have had cataract surgery.
* They have had corneal refractive surgery.
* They have any corneal distortion resulting from previous hard or rigid lens wear or have keratoconus.
* They are pregnant or lactating.
* They have any ocular abnormality which would, in the opinion of the investigator, normally contraindicate contact lens wear.
* They have any infectious disease which would, in the opinion of the investigator, contraindicate contact lens wear or pose a risk to study personnel; or they have any immunosuppressive disease (e.g. HIV), or a history of anaphylaxis or severe allergic reaction.
* They have taken part in any other contact lens or care solution clinical trial or research, within two weeks prior to starting this study.
Minimum Eligible Age

18 Years

Maximum Eligible Age

40 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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CooperVision, Inc.

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Eurolens Research - The University of Manchester

Manchester, , United Kingdom

Site Status

Countries

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United Kingdom

Provided Documents

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Document Type: Study Protocol and Statistical Analysis Plan

View Document

Other Identifiers

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EX-MKTG-85

Identifier Type: -

Identifier Source: org_study_id

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