Relationship Between Serum Apolipoprotein Levels and Weight Loss in Patients Undergoing Sleeve Gastrectomy for Morbid Obesity

NCT ID: NCT07325916

Last Updated: 2026-01-08

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

ACTIVE_NOT_RECRUITING

Total Enrollment

110 participants

Study Classification

OBSERVATIONAL

Study Start Date

2025-05-01

Study Completion Date

2026-06-30

Brief Summary

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The study looks at whether a specific protein in the blood, called apolipoprotein, can predict how much weight a person might lose after sleeve gastrectomy, a surgery for people with severe obesity. We want to find a specific level of this protein that shows which patients are most likely to lose weight successfully after surgery. By identifying this level, we hope to guide doctors in deciding who should have the surgery and who might do better with non-surgical weight loss methods.

Detailed Description

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The subject of our research is whether serum apolipoprotein levels can be a predictive value for weight loss in patients who will undergo sleeve gastrectomy due to morbid obesity. Our aim is to determine a cut-off value for patients who benefit most from bariatric surgery based on preoperative serum apolipoprotein levels. By including this value among the surgical indications, we plan to direct patients less likely to benefit from surgery to conservative approaches.

Conditions

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Morbid Obesity Requiring Bariatric Surgery

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Sleeve Gastrectomy Patients

Patients who meet inclusion criteria for the study undergoing sleeve gastrectomy

Laparoscopic Sleeve Gastrectomy

Intervention Type PROCEDURE

Laparoscopic Sleeve Gastrectomy

Interventions

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Laparoscopic Sleeve Gastrectomy

Laparoscopic Sleeve Gastrectomy

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Patients aged 18 to 75
* International Classification of Diseases (ICD) code E66 diagnosis (obesity)
* Patients who have given consent for sleeve gastrectomy
* Patients who are suitable for general anesthesia

Exclusion Criteria

* Patients who did not give consent to be included in the study
* Patients who are scheduled for surgery other than sleeve gastrectomy
Minimum Eligible Age

18 Years

Maximum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Yigit DUZKOYLU

OTHER_GOV

Sponsor Role lead

Responsible Party

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Yigit DUZKOYLU

Associate Professor

Responsibility Role SPONSOR_INVESTIGATOR

Locations

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Basaksehir Cam and Sakura City Hospital

Istanbul, Basaksehir, Turkey (Türkiye)

Site Status

Countries

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Turkey (Türkiye)

Other Identifiers

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2024-KAEK-11 134

Identifier Type: -

Identifier Source: org_study_id

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