Comparison of Fractionated Versus Bolus Administration of Different Doses of Hyperbaric Bupivacaine Combined With Opioids in Spinal Anesthesia for Caesarean Section
NCT ID: NCT07249814
Last Updated: 2025-11-25
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.
COMPLETED
NA
99 participants
INTERVENTIONAL
2024-06-30
2025-06-15
Brief Summary
Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.
Related Clinical Trials
Explore similar clinical trials based on study characteristics and research focus.
Comparison of Intrathecal Bupivacaine With and Without Morphine for Post-operative Analgesia in Parturients Undergoing Elective Cesarean Section: A Randomized Controlled Trial
NCT07094802
Comparison of Meperidine and Sufentanil Added to 0.5% Hyperbaric Bupivacaine for Spinal Anesthesia in Cesarean Section
NCT04446715
Sequential and Mixture Injection of Opioids and Hyperbaric Bupivacaine
NCT04403724
Comparison Between Hyperbaric Bupivacaine With Fentanyl vs. Hyperbaric Bupivacaine With Dexmedetomidine in Reducing Visceral Pain During Cesarean Delivery Under Spinal Anaesthesia
NCT06367660
Intrathecal Injection of Hyperbaric Bupivacaine Versus a Mixture of Hyperbaric and Isobaric Bupivacaine in Patients Undergoing Lower Abdominal Surgery
NCT06050044
Detailed Description
Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.
Conditions
See the medical conditions and disease areas that this research is targeting or investigating.
Study Design
Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.
RANDOMIZED
PARALLEL
OTHER
SINGLE
Study Groups
Review each arm or cohort in the study, along with the interventions and objectives associated with them.
Bolus bupivacaine (0.07 mg/cm)
Bolus anesthesia
• Group B: received a bolus administration of the total dose of 0.5% hyperbaric bupivacaine (0.07 mg/cm height)
Fractionated bupivacaine (0.07 mg/cm)
Fractionated anesthesia
* Group F7: received a fractionated administration of bupivacaine (0.07 mg/cm);
* Group F6: received a fractionated administration of the reduced dose of bupivacaine (0.06 mg/cm).
Fractionated bupivacaine (0.06 mg/cm)
Fractionated anesthesia
* Group F7: received a fractionated administration of bupivacaine (0.07 mg/cm);
* Group F6: received a fractionated administration of the reduced dose of bupivacaine (0.06 mg/cm).
Interventions
Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.
Fractionated anesthesia
* Group F7: received a fractionated administration of bupivacaine (0.07 mg/cm);
* Group F6: received a fractionated administration of the reduced dose of bupivacaine (0.06 mg/cm).
Bolus anesthesia
• Group B: received a bolus administration of the total dose of 0.5% hyperbaric bupivacaine (0.07 mg/cm height)
Eligibility Criteria
Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.
Inclusion Criteria
* ASA physical status II-III
* age 18-50 years
* height from 140 to 180 cm
* body weight from 40 to 130 kg
Exclusion Criteria
* contraindications to spinal anesthesia
* allergy to amide-type local anesthetics
18 Years
50 Years
FEMALE
No
Sponsors
Meet the organizations funding or collaborating on the study and learn about their roles.
Bogomolets National Medical University
OTHER
Responsible Party
Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.
Kateryna Bielka
Prof.
Locations
Explore where the study is taking place and check the recruitment status at each participating site.
Kyiv Perinatal Center
Kyiv, , Ukraine
Countries
Review the countries where the study has at least one active or historical site.
Other Identifiers
Review additional registry numbers or institutional identifiers associated with this trial.
196
Identifier Type: -
Identifier Source: org_study_id
More Related Trials
Additional clinical trials that may be relevant based on similarity analysis.