AI-driven Clinical Decision Support for Perioperative Blood Orders

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

50 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-10-28

Study Completion Date

2027-01-01

Brief Summary

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20 million patients have surgery in the United States every year, with approximately 1 million of those patients requiring life-saving blood transfusion. Presurgical preparation for transfusion is important to allow for safe and timely transfusion during surgery; however, excessive preparation is unfortunately common, costly, and contributes to blood waste. This study aims to evaluate an intelligent clinical decision support system that helps clinicians prepare blood for patients who are likely to need it, while avoiding excessive preparation for patients who don't, potentially improving patient safety while reducing blood waste and healthcare costs.

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Detailed Description

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Conditions

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Surgery

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Stepped-wedge cluster randomized trial

Primary Study Purpose

SCREENING

Blinding Strategy

NONE

Study Groups

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Usual care

Usual care for determining presurgical blood orders, including use of the institutional Maximum Surgical Blood Ordering Schedule (MSBOS)

Group Type ACTIVE_COMPARATOR

Usual care

Intervention Type OTHER

Including use of the conventional Maximum Surgical Blood Ordering Schedule (MSBOS)

S-PATH

Access to the S-PATH clinical decision support system

Group Type EXPERIMENTAL

S-PATH clinical decision support system

Intervention Type OTHER

Access to the S-PATH electronic health record (EHR)-integrated clinical decision support system

Interventions

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S-PATH clinical decision support system

Access to the S-PATH electronic health record (EHR)-integrated clinical decision support system

Intervention Type OTHER

Usual care

Including use of the conventional Maximum Surgical Blood Ordering Schedule (MSBOS)

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Scheduled for surgery in one of the main operating room areas (non-remote) at Barnes Jewish Hospital
* Evaluated in-person at one of the preoperative assessment clinics affiliated with BJC Healthcare
* Have a valid S-PATH model prediction prior to their preoperative assessment clinic visit

Exclusion Criteria

* Clinician (resident physician or advanced practice provider) who works at a preoperative assessment clinic

* None

* Pregnant
* Presence or history of red cell alloantibodies

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No