Edge of Laminar Block Versus Erector Spinae Plane Block for Postoperative Analgesia in Video-Assisted Thoracoscopic Surgery

NCT ID: NCT07201285

Last Updated: 2025-10-02

Basic Information

• Recruitment Status: RECRUITING
• Clinical Phase: NA
• Total Enrollment: 70 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2025-10-01
• Study Completion Date: 2026-04-01

Brief Summary

This study aims to compare the ultrasound-guided edge of laminar block (ELB) and erector spinae plane block (ESPB) for postoperative analgesia in patients undergoing video-assisted thoracic surgery (VATS).

Detailed Description

Postoperative pain after thoracic surgery, which is attributed to muscle incisions, rib retractions, and intercostal nerve damage, may be severe enough to cause pulmonary complications, such as atelectasis, pneumonia, and increased oxygen consumption.

The erector spinae plane block (ESPB) is used for managing post-thoracotomy pain and has numerous advantages that make it an attractive alternative technique. The ESPB injects a local anaesthetic around the erector spinae muscle at approximately the level of the T5. It may be able to block the dorsal and ventral rami of the thoracic spinal nerves.

A novel technique of retrolaminar block (RLB) called the edge of laminar block (ELB) to provide sensory analgesia during rib fracture surgery.

Conditions

Edge of Laminar Block; Erector Spinae Plane Block; Postoperative Analgesia; Video-Assisted Thoracoscopic Surgery

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: TREATMENT
• Blinding Strategy: DOUBLE

Study Groups

ELB group

Patients will receive edge of laminar block using 20ml of bupivacaine 0.25%.

Group Type: EXPERIMENTAL

Edge of laminar block

Intervention Type: OTHER

Patients will receive edge of laminar block using 20ml of bupivacaine 0.25%.

ESPB group

Patients will receive an erector spinae plane block using 20ml of bupivacaine 0.25%.

Group Type: EXPERIMENTAL

Erector spinae plane block

Intervention Type: OTHER

Patients will receive an erector spinae plane block using 20ml of bupivacaine 0.25%.

Interventions

Edge of laminar block

Patients will receive edge of laminar block using 20ml of bupivacaine 0.25%.

Intervention Type: OTHER

Erector spinae plane block

Patients will receive an erector spinae plane block using 20ml of bupivacaine 0.25%.

Intervention Type: OTHER

Eligibility Criteria

Inclusion Criteria

• Age from 18 to 65 years.
• Both sexes.
• American Society of Anesthesiology (ASA) physical status I-II.
• Undergoing video-assisted thoracic surgery (VATS) under general anesthesia.

Exclusion Criteria

• History of allergies to local anesthetics.
• Opioid dependency.
• Bleeding or coagulation disorders.
• Psychiatric and neurological disorder.
• Local infection at the site of injection.
• Severe heart, lung, liver, and renal dysfunction.
• Pregnant or lactating women.

• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 65 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Tanta University

OTHER

Sponsor Role: lead

Responsible Party

Mohammed Said ElSharkawy

Lecturer of Anesthesiology, Surgical Intensive Care and Pain Medicine, Faculty of Medicine, Tanta University, Tanta, Egypt

Responsibility Role: PRINCIPAL_INVESTIGATOR

Locations

Tanta University

Tanta, El-Gharbia, Egypt

Site Status: RECRUITING

Countries

Egypt

Central Contacts

Mohammed S Elsharkawy, MD

Role: CONTACT

mselsharkawy@med.tanta.edu.eg

00201148207870

Facility Contacts

Mohammed S Elsharkawy, MD

Role: primary

mselsharkawy@med.tanta.edu.eg

00201148207870

Other Identifiers

36264PR1336/8/25

Identifier Type: -

Identifier Source: org_study_id