A Comparative Study of Portable Patch-type Carotid Ultrasound CADFlow and Desktop Ultrasound Machines

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

NOT_YET_RECRUITING

Total Enrollment

140 participants

Study Classification

OBSERVATIONAL

Study Start Date

2025-10-01

Study Completion Date

2025-12-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

observational study The purpose of this observational study is to clarify the consistency, accuracy, and reproducibility of portable patch carotid ultrasound (CADFlow) compared to desktop ultrasound machines in detecting cardiac output (CO), peak velocity (Vmax), and minimum velocity (Vmin) in healthy volunteers.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Head-mounted Display for Central Venous Catheterization

NCT06469034

Central Venous Catheterization

COMPLETED NA

The Relation Between Common Carotid Artery Diameter and Central Venous Pressure for Assessment of Intravascular Fluid Status After Major Surgeries: An Observational Study

NCT04018443

Fluid Resuscitation Monitoring Non-invasively

UNKNOWN

Central Venous Catheter-Related Thrombosis in Critically Ill Patients

NCT06573112

Catheter Related Complication

COMPLETED

Daily Ultrasound-screening for CVC-related Thrombosis

NCT03327376

Central Venous Catheter Thrombosis Critical Illness Ultrasonography

COMPLETED

Supraclavicular Fossa US View for Catheter Positioning in Right Subclavian Central Venous Catheterization

NCT03812757

Central Venous Catheter Placement

COMPLETED

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Parameters including cardiac output (CO), peak carotid artery velocity (Vmax), and minimum velocity (Vmin) were monitored in healthy subjects using a portable patch-type carotid ultrasound device (CADFlow). The subjects were placed in a supine position with the head rotated 30° to the contralateral side and the neck slightly extended. The dual-patch probe was then attached to the sites of the most prominent bilateral carotid artery pulsations. The automatic measurement mode was initiated to record blood flow waveforms for 60 seconds. After 30 minutes, the same subjects underwent reassessment of the aforementioned parameters using a conventional ultrasound system. The distal internal diameters of the bilateral common carotid arteries were measured in two-dimensional mode (mean of three measurements). Using pulsed-wave Doppler with an insonation angle ≤60°, Vmax and Vmin were recorded over three consecutive cardiac cycles. The probe was subsequently switched to a transthoracic cardiac probe for CO measurement at the left ventricular outflow tract (LVOT) (mean of three consecutive measurements). The order in which the subjects were monitored with the two devices was randomized.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Device Replacement

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

cohort of healthy adults

Monitoring hemodynamic parameters in healthy subjects using two distinct devices

Evaluating the Consistency and Accuracy of Two Devices in Monitoring Hemodynamic Parameters

Intervention Type DIAGNOSTIC_TEST

This portable patch-type carotid ultrasound has not yet been used in clinical settings.

Hemodynamic monitoring

Intervention Type DEVICE

Whether the parameters monitored by portable patch-based ultrasound devices agree with the gold standard has not yet been thoroughly validated

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Evaluating the Consistency and Accuracy of Two Devices in Monitoring Hemodynamic Parameters

This portable patch-type carotid ultrasound has not yet been used in clinical settings.

Intervention Type DIAGNOSTIC_TEST

Hemodynamic monitoring

Whether the parameters monitored by portable patch-based ultrasound devices agree with the gold standard has not yet been thoroughly validated

Intervention Type DEVICE

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Age between 18 and 79 years; No abnormalities found in physical examination; Signed informed consent form.

Exclusion Criteria

* Previous or current cardiovascular or cerebrovascular diseases; Carotid intima-media thickness (IMT) ≥ 1.0 mm or plaque; Arrhythmia; ④ BMI \> 35 kg/m²; Pregnancy.

Minimum Eligible Age

18 Years

Maximum Eligible Age

79 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes