Daily Ultrasound-screening for CVC-related Thrombosis

NCT ID: NCT03327376

Last Updated: 2022-10-24

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

1262 participants

Study Classification

OBSERVATIONAL

Study Start Date

2017-12-01

Study Completion Date

2022-01-01

Brief Summary

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The central venous catheters (CVC) related thrombosis is an issue of importance to ICU clinicians.This study conducts the daily ultrasound-screening for CVC-related thrombosis (DUCT).Its aim is to evaluate the characteristic and regularity of the central venous catheters (CVC) related thrombosis in ICU patients, and optimize the screening program of CVC-related thrombosis.

Detailed Description

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Conditions

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Central Venous Catheter Thrombosis Critical Illness Ultrasonography

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Characteristic and regularity of CRT

The patients who have a central venous catheterization conduct the daily ultrasound-screening for CVC-related Thrombosis (DUCT).

ultrasound-screening

Intervention Type DEVICE

Daily ultrasound-screening for CVC-related thrombosis (DUCT) by compression ultrasound and color doppler ultrasound.

Interventions

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ultrasound-screening

Daily ultrasound-screening for CVC-related thrombosis (DUCT) by compression ultrasound and color doppler ultrasound.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Consecutive patients at least 18 years of age, expected to need a central venous catheterization for at least 48h in ICU.

Exclusion Criteria

* Patients with infection or inflammation or local trauma at the insertion site.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Second Affiliated Hospital, School of Medicine, Zhejiang University

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Mao Zhang, MD

Role: STUDY_DIRECTOR

2nd Affiliated Hospital, Zhejiang University School of Medicine Institute of Emergency Medicine, Zhejiang University

Weidong Tang, MD

Role: PRINCIPAL_INVESTIGATOR

The First People's Hospital of Fuyang District

Zhiping Huang, MD

Role: PRINCIPAL_INVESTIGATOR

Beilun District People's Hospital

Zhaohui Ji, MD

Role: PRINCIPAL_INVESTIGATOR

The First People's Hospital of Huzhou

Hong Liu, MD

Role: PRINCIPAL_INVESTIGATOR

Lishui Country People's Hospital

Lingcong Wang, MD

Role: PRINCIPAL_INVESTIGATOR

The First Affiliated Hospital of Zhejiang University of traditional Chinese Medicine

Mingwei Huang, MD

Role: PRINCIPAL_INVESTIGATOR

Jinhua Central Hospital

Xingwen Zhang, MD

Role: PRINCIPAL_INVESTIGATOR

Hunan People's Hospital

Yunchao Shi, MD

Role: PRINCIPAL_INVESTIGATOR

Affiliated Hospital of Jiaxing University

Renfei Shan, MD

Role: PRINCIPAL_INVESTIGATOR

Taizhou Hospital

Fuzheng Tao, MD

Role: PRINCIPAL_INVESTIGATOR

Taizhou Hospital of integrated traditional Chinese and Western Medicine

Yi Wang, MD

Role: PRINCIPAL_INVESTIGATOR

First People's Hospital of Hangzhou

Qijiang Chen, MD

Role: PRINCIPAL_INVESTIGATOR

Ninghai First Hospital

Ning Zhang, MD

Role: PRINCIPAL_INVESTIGATOR

Lishui Country People's Hospital

Jian Hu, MD

Role: PRINCIPAL_INVESTIGATOR

Pinghu first people's Hospital

Dengpan Lai, MD

Role: PRINCIPAL_INVESTIGATOR

Affiliated Hospital of Hangzhou Teacher's University

Yingru Lu, MD

Role: PRINCIPAL_INVESTIGATOR

First Affiliated Hospital of Wenzhou Medical University

Xudong Zheng, MD

Role: PRINCIPAL_INVESTIGATOR

The Third Affiliated Hospital of Wenzhou Medical University

Jianbo Gao, MD

Role: PRINCIPAL_INVESTIGATOR

The First People's Hospital of Fuyang District

Bei Tang, MD

Role: PRINCIPAL_INVESTIGATOR

Jiande First People's Hospital

Wansheng Li, MD

Role: PRINCIPAL_INVESTIGATOR

Taizhou Hospital

Xiaoyuan Shen, MD

Role: PRINCIPAL_INVESTIGATOR

Xiaoshan first people's Hospital

Yukang Song, MD

Role: PRINCIPAL_INVESTIGATOR

Affiliated Wenling Hospital of Wenzhou Medical University

Guojuan Ding, MD

Role: PRINCIPAL_INVESTIGATOR

Shaoxing People's Hospital

Feng Wu, MD

Role: PRINCIPAL_INVESTIGATOR

Zhejiang Quhua Hospital

Xin Tian, MD

Role: PRINCIPAL_INVESTIGATOR

The Central Hospital of Lishui City

Shaoyi Xu, MD

Role: PRINCIPAL_INVESTIGATOR

The Second Affiliated Hospital of Jiaxing University

Weijun Fang, MD

Role: PRINCIPAL_INVESTIGATOR

The Central Hospital of Lishui City

LIfeng Wu, MD

Role: PRINCIPAL_INVESTIGATOR

Yuyao People's Hospital

Locations

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2nd Affiliated Hospital, Zhejiang University School of Medicine Institute of Emergency Medicine, Zhejiang University

Hanzhou, Zhejiang, China

Site Status

Countries

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China

References

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Faustino EV, Spinella PC, Li S, Pinto MG, Stoltz P, Tala J, Card ME, Northrup V, Baker KE, Goodman TR, Chen L, Silva CT. Incidence and acute complications of asymptomatic central venous catheter-related deep venous thrombosis in critically ill children. J Pediatr. 2013 Feb;162(2):387-91. doi: 10.1016/j.jpeds.2012.06.059. Epub 2012 Aug 9.

Reference Type BACKGROUND
PMID: 22883418 (View on PubMed)

Lee AY, Kamphuisen PW. Epidemiology and prevention of catheter-related thrombosis in patients with cancer. J Thromb Haemost. 2012 Aug;10(8):1491-9. doi: 10.1111/j.1538-7836.2012.04817.x.

Reference Type BACKGROUND
PMID: 22703114 (View on PubMed)

Refaei M, Fernandes B, Brandwein J, Goodyear MD, Pokhrel A, Wu C. Incidence of catheter-related thrombosis in acute leukemia patients: a comparative, retrospective study of the safety of peripherally inserted vs. centrally inserted central venous catheters. Ann Hematol. 2016 Dec;95(12):2057-2064. doi: 10.1007/s00277-016-2798-4. Epub 2016 Aug 20.

Reference Type BACKGROUND
PMID: 27542955 (View on PubMed)

Parienti JJ, Mongardon N, Megarbane B, Mira JP, Kalfon P, Gros A, Marque S, Thuong M, Pottier V, Ramakers M, Savary B, Seguin A, Valette X, Terzi N, Sauneuf B, Cattoir V, Mermel LA, du Cheyron D; 3SITES Study Group. Intravascular Complications of Central Venous Catheterization by Insertion Site. N Engl J Med. 2015 Sep 24;373(13):1220-9. doi: 10.1056/NEJMoa1500964.

Reference Type RESULT
PMID: 26398070 (View on PubMed)

Gentile A, Petit L, Masson F, Cottenceau V, Bertrand-Barat J, Freyburger G, Pinaquy C, Leger A, Cochard JF, Sztark F. Subclavian central venous catheter-related thrombosis in trauma patients: incidence, risk factors and influence of polyurethane type. Crit Care. 2013 May 29;17(3):R103. doi: 10.1186/cc12748.

Reference Type RESULT
PMID: 23718723 (View on PubMed)

Other Identifiers

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z2jzk

Identifier Type: -

Identifier Source: org_study_id

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