Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
129 participants
OBSERVATIONAL
2021-06-03
2022-09-04
Brief Summary
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The main questions it aims to answer is:
* Can biomarkers indicating neurodegeneration and neuroinflammation be correlated with preoperative frailty and cognitive functions?
* Can these biomarkers be used as potential tools for early identification in vulnarable populations?
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Detailed Description
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Conditions
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Study Design
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OTHER
CROSS_SECTIONAL
Study Groups
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age 65-74
assessment Mini mental state examination
pre operatively four weeks postoperatively
assessment FRAIL scale
pre operatively four weeks postoperatively
collecting cerebrospinal fluid during regional anesthesia
In the operating room regional anesthesia was administered according to the surgical plan
Interventions
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assessment Mini mental state examination
pre operatively four weeks postoperatively
assessment FRAIL scale
pre operatively four weeks postoperatively
collecting cerebrospinal fluid during regional anesthesia
In the operating room regional anesthesia was administered according to the surgical plan
Eligibility Criteria
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Inclusion Criteria
* \>65 age patients
Exclusion Criteria
* uncontrolled hypertension
* alchohol dependence
* renal failure
* active liver disease
* cancer-related or emergency surgery
* unwillingness to participate
65 Years
ALL
No
Sponsors
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Baskent University
OTHER
Responsible Party
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ELVIN KESIMCI
prof. dr
Locations
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Baskent University Ankara Hospital
Ankara, , Turkey (Türkiye)
Countries
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References
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Fang J, Liang H, Chen M, Zhao Y, Wei L. Association of preoperative cognitive frailty with postoperative complications in older patients under general anesthesia: a prospective cohort study. BMC Geriatr. 2024 Oct 19;24(1):851. doi: 10.1186/s12877-024-05431-1.
Other Identifiers
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KA21/124
Identifier Type: -
Identifier Source: org_study_id
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