Analyses of Cerebrospinalfluid in Patients With Delirium

NCT ID: NCT05060614

Last Updated: 2024-03-12

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

700 participants

Study Classification

OBSERVATIONAL

Study Start Date

2016-09-01

Study Completion Date

2027-12-30

Brief Summary

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The current project aims to measure biomarkers in the cerebrospinalfluid (CSF) and serum samples from patients with delirium. We hope to uncover new insights into the pathophysiology of delirium and explore its link to dementia.

Detailed Description

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Delirium is a common and serious complication to acute illness, and is characterized by acute disturbances in attention, awareness, and cognition. Dementia is a major risk factor of delirium, and delirium increases the risk of dementia progression and development. As the conditions share both clinical and epidemiological features, some researchers suggest that also pathophysiological links are shared. Understanding delirium pathophysiology, which is poorly understood, may thus help elucidate early molecular mechanisms in dementia.

This study aims to to increase our understanding of the pathophysiology of delirium and molecular links between delirium and dementia, by exploring cerebrospinal fluid (CSF) biomarkers.

Conditions

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Delirium

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Interventions

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Hip fracture surgery

Hip fracture surgery

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Patients with acute hip fracture

Exclusion Criteria

* Moribund patients.
* Lack of consent
Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Oslo University Hospital

OTHER

Sponsor Role lead

Responsible Party

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Leiv Otto Watne

Postdoctoral Research Fellow

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Leiv O Watne, PhD

Role: PRINCIPAL_INVESTIGATOR

Oslo University Hospital

Locations

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Leiv Otto Watne

Oslo, Other, Norway

Site Status RECRUITING

Countries

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Norway

Central Contacts

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Leiv O Watne, PhD

Role: CONTACT

Facility Contacts

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Leiv O Watne, PhD

Role: primary

Other Identifiers

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2016/1368

Identifier Type: -

Identifier Source: org_study_id

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