Correlation Between the Midpalatal Suture Maturity and the Maxillary Third Molar Mineralization: a CBCT Study

NCT ID: NCT07181707

Last Updated: 2025-09-26

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Total Enrollment

200 participants

Study Classification

OBSERVATIONAL

Study Start Date

2025-10-01

Study Completion Date

2026-09-01

Brief Summary

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Assessing the maturation of the mid-palatal suture is an essential criterion for orthodontic decision-making. However, from a CBCT according to Angelieri's classification , it remains difficult for the practitioner's untrained eye.

As profile teleradiographs are almost routinely performed in orthodontic check-ups, numerous studies have looked for a correlation between the stage of maturation of the palatal suture and that of the cervical vertebrae. Some have also looked for a link with mineralization of mandibular third or second molars according to Demirjian's classification.

These techniques would provide a reliable and reproducible method without the use of CBCT.

In our study, the investigators will be looking for a correlation with mineralization of the maxillary third molar according to Nolla's classification. The latter has become common in practice and easy to apply on an orthopantomogram.

This would simplify decision-making without the need for a CBCT, but by using the orthopantomogram which is already routinely performed during the assessment.

Detailed Description

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The study is a non-interventional (observational) research involving the human person, research on existing data (retrospective study).

This study analyzes the maturation stage of the Midpalatal suture and the mineralization of the third left molar.

This is a comparative retrospective study of radiographs in three dimensions before any orthodontic treatment to study a potential correlation.

There is no control group but there are subgroups depending of the age of the patients.

Conditions

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Maturation of the Midpalatal Suture and Maxillary Third Molar Mineralization in Healthy Individuals

Study Design

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Observational Model Type

OTHER

Study Time Perspective

RETROSPECTIVE

Study Groups

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Patient aged under 14 years

Patients aged under 14 years.

No interventions assigned to this group

Patients aged between 14 and 18 years.

Patients aged between 14 and 18 years.

No interventions assigned to this group

Patients aged between 19 and 25 years.

Patients aged between 19 and 25 years.

No interventions assigned to this group

Patients aged over 25 years.

Patients aged over 25 years.

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* No previous orthodontic or orthopedic treatment
* At least the maxillary third left molar
* No skeletal disability

Exclusion Criteria

* Previous maxillofacial trauma
* Dentofacial deformities
* Endocrinological pathologies with implications for maxillofacial growth • - Syndromes
* History of maxillofacial or orthognathic surgery
* History of orthodontic treatment
* Incomplete data or incomplete CBCT
* Maxillary third left molar fracture/cavity/other deterioratedation
Minimum Eligible Age

9 Years

Maximum Eligible Age

40 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Central Hospital, Nancy, France

OTHER

Sponsor Role lead

Responsible Party

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VANDE VANNET Bart

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Bart VANDE VANNET, PhD

Role: STUDY_DIRECTOR

Central Hospital, Nancy, France

Locations

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Caroline Bertazzon

Nancy, France, France

Site Status

Countries

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France

Central Contacts

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Bart VANDE VANNET, PhD

Role: CONTACT

+32496284339

Caroline BERTAZZON

Role: CONTACT

+33638657700

Facility Contacts

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Caroline Bertazzon, Intern

Role: primary

+33638657700

Other Identifiers

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2025PI009

Identifier Type: -

Identifier Source: org_study_id

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