Effect of Dexmedetomidine Infusion on Post Anesthesia Discharge Time

NCT ID: NCT07180810

Last Updated: 2025-09-23

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

82 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-09-05

Study Completion Date

2025-08-20

Brief Summary

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A randomised control trial evaluating the effect of low dose dexmedetomidine infusion on post anesthesia discharge time in patients of day case breast cancer surgery compared with placebo infusion. The primary outcome was to compare the frequency of early discharge in each group.

Detailed Description

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A prospective Randomised control trial evaluating the effect of low dose dexmedetomidine infusion on post anesthesia discharge time in patients of day case breast cancer surgery compared with placebo infusion. The primary outcome was to compare the frequency of early discharge in each group. Early discharge was defined as within two hours. The sample size was of 82 female patients with a specific inclusion and exclusion criteria. Randomisation was done through computer software and the trial was double blinded. SPSS version 22 will be used for data analysis.

Conditions

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Post Anesthesia Discharge Time in Patients of Breast Cancer Surgery

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Group A being administered low dose intravenous dexmedetomidine infusion vs Group B being admissions IV normal saline infusion at rate 0.6mcg/kg/hour rate
Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Caregivers
Double blinded study, all participants, and the care provider providing anesthesia to the participants were blinded

Study Groups

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Group A, receiving low dose dexmedetomidine infusion

Group A, receiving low dose dexmedetomidine infusion at 0.6mcg/kg/hour rate

Group Type EXPERIMENTAL

Dexmedetomidine infusion low dose

Intervention Type DRUG

low dose dexmedetomidine infusion at rate 0.6mcg/kg/hour rate .

Group B, receiving normal saline infusion as placebo

normal saline being used as placebo at rate 0.6mch/kg/hour rate

Group Type PLACEBO_COMPARATOR

Group B receiving normal saline

Intervention Type DRUG

Normal saline infusion at rate 0.6mcg/kr/hour rate

Interventions

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Dexmedetomidine infusion low dose

low dose dexmedetomidine infusion at rate 0.6mcg/kg/hour rate .

Intervention Type DRUG

Group B receiving normal saline

Normal saline infusion at rate 0.6mcg/kr/hour rate

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Age 18-60 yrs, ASA 1 and 2, elective breast cancer surgery

Exclusion Criteria

* BMI greater than 35, CKD stage 3 or greater, known drug allergy to study drug, bradycardia, history of PONV, patients on antiepileptics
Minimum Eligible Age

18 Years

Maximum Eligible Age

60 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Shaukat Khanum Memorial Cancer Hospital & Research Centre

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Almas nil Iqbal, FRCA

Role: STUDY_CHAIR

Shaukat Khanum Memorial Cancer Hospital and Research Centre, Lahore

Locations

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Shaukat Khanum Memorial Cancer Hospital and Research Centre

Lahore, Pubjab, Pakistan

Site Status

Countries

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Pakistan

Related Links

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Other Identifiers

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IRB-23-14

Identifier Type: -

Identifier Source: org_study_id

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