Multicentre Longitudinal Study of Bone Mineralisation Characteristics in Marfan Syndrome and Ehlers-Danlos Syndrome
NCT ID: NCT07169669
Last Updated: 2025-09-12
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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NOT_YET_RECRUITING
150 participants
OBSERVATIONAL
2025-10-31
2026-05-31
Brief Summary
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In particular we intend to obtain data regarding the characteristics of bone mineralisation, as well as their variation over time and the relationships existing with other clinical-anamnestic parameters, in patients with Marfan syndrome or Ehlers-Danlos syndrome by retrospectively analysing (data already collected for normal clinical practice and already available at the hospital) the case history of the Cardiovascular genetic center at IRCCS Policlinico San Donato and the related Computerized Bone Mineralometry (MOC) examinations performed at the Radiology Service of the same hospital between 1 September 2019 and 31 December 2022.
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Detailed Description
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Conditions
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Study Design
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COHORT
RETROSPECTIVE
Study Groups
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Marfan group
Adult and paediatric subjects with Marfan syndrome referred to the Centre for Cardiovascular Genetic of IRCCS Policlinico San Donato
No interventions assigned to this group
Ehlers Danlos group
Adult and paediatric subjects with Ehlers Danlos Syndrome referred to the Centre for CardioVascular Genetics of IRCCS Policlinico San Donato and the Reference Centre for Ehlers-Danlos Syndromes Fondazione IRCCS Ca' Granda - Ospedale Maggiore Policlinico
No interventions assigned to this group
Eligibility Criteria
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Inclusion Criteria
* Adult and paediatric subjects who have performed at least one Bone Mineral Densitometry within the observation period of the study.
Exclusion Criteria
* Presence of prostheses in the coxofemoral joint;
* Oncological bone diseases reported in history.
ALL
No
Sponsors
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Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
OTHER
IRCCS Policlinico S. Donato
OTHER
Responsible Party
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Central Contacts
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Alessandro Pini Alessandro Giorgio Pini,MD, Medical degree
Role: CONTACT
Other Identifiers
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BONE
Identifier Type: -
Identifier Source: org_study_id
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