Effectiveness of Isokinetic Exercises in Proprioception for Post-stroke Patients

NCT ID: NCT07106619

Last Updated: 2025-08-06

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

34 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-07-24

Study Completion Date

2026-03-31

Brief Summary

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Somatosensory dysfunction including the sense of movement and position, i.e. proprioception, is observed in approximately 65% of patients after stroke. Loss of muscle strength, especially in the lower extremities, and impaired proprioception lead to significant loss of function in stroke patients. In addition, recent studies have emphasised that sensory information obtained by target-oriented exercises plays an important role in neuroplasticity and proprioception is an important element. The aim of this study was to evaluate the effect of knee isokinetic muscle strengthening exercises on proprioception and balance in stroke patients.

Detailed Description

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Conditions

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Stroke

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Conventional Rehabilitation

Patients will receive 15 sessions of conventional rehabilitation

Group Type ACTIVE_COMPARATOR

Conventional rehabilitation program

Intervention Type OTHER

Ambulation and balance exercises

isokinetic Exercise

Patients will receive 15 sessions of conventional rehabilitation and 10 sessions of knee isokinetic strengthening exercise therapy for the paretic lower extremity for 3 weeks. Isokinetic strengthening exercises will be performed using Cybex 770, Humac Norm dynamometer (CSMI, Stoughton, MA, USA).

Group Type EXPERIMENTAL

Isokinetic Exercises

Intervention Type DEVICE

Exercises will be performed at three different angular speeds (90 ̊/sec, 5 repetitions, 5 sets; 120 ̊/sec, 8 repetitions, 5 sets; 150 ̊/sec, 10 repetitions, 5 sets).

Conventional rehabilitation program

Intervention Type OTHER

Ambulation and balance exercises

Interventions

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Isokinetic Exercises

Exercises will be performed at three different angular speeds (90 ̊/sec, 5 repetitions, 5 sets; 120 ̊/sec, 8 repetitions, 5 sets; 150 ̊/sec, 10 repetitions, 5 sets).

Intervention Type DEVICE

Conventional rehabilitation program

Ambulation and balance exercises

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* At least 3 months and no more than 1 year must have passed since the date of the incident
* Be between 35 and 75 years of age
* Manual muscle testing of the affected lower extremity shows at least 3 in ankle dorsiflexion and knee extension
* No limitation in passive joint range of motion in the lower extremity
* Mini mental test score \> 23

Exclusion Criteria

* Presence of spasticity according to the modified Ashworth scale \> 1+
* Presence of neurological disease other than stroke
* Presence of other medical conditions that may cause sensorimotor dysfunction in the lower extremities (e.g., diabetic polyneuropathy)
* Presence of orthopaedic problems affecting lower extremity function
* Previous history of stroke or ischaemic attack
* Poor general health status (e.g. severe heart failure, COPD)
Minimum Eligible Age

35 Years

Maximum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Ankara Etlik City Hospital

OTHER_GOV

Sponsor Role lead

Responsible Party

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Ayse Naz Kalem

specialist

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Ankara Etlik City Hospital

Ankara, Yenimahalle, Turkey (Türkiye)

Site Status RECRUITING

Countries

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Turkey (Türkiye)

Central Contacts

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Ayşe Naz Kalem Özgen, specialist

Role: CONTACT

+90 0312 797 00 00

Facility Contacts

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Ayşe Naz Kalem Özgen

Role: primary

+90 0312 797 00 00

Other Identifiers

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AEŞH-EK-2025-012

Identifier Type: -

Identifier Source: org_study_id

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