Immediate Effects of Open and Closed Kinetic Chain Exercises on Upper Extremity in Stroke Patients.

NCT ID: NCT06272175

Last Updated: 2025-04-16

Basic Information

• Recruitment Status: RECRUITING
• Clinical Phase: NA
• Total Enrollment: 50 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2024-03-04
• Study Completion Date: 2025-12-30

Brief Summary

Stroke is a sudden disruption of blood flow to the brain, resulting in physical and mental disabilities. It's a global health issue affecting millions each year, often leading to paralysis, altered muscle tone, and loss of motor control and balance. This study aims to examine the immediate effects of open and closed kinetic chain activites on upper extremity spasticity and motor dexterity in hemiplegic patients. This study will be conducted simultaneously at İstinye University Hospital Medical Park Gaziosmanpaşa and İstinye University Physiotherapy and Rehabilitation Application and Research Center (İSÜFİZYOTEM). 50 stroke patients will be included in the study, and all participants will be asked to sign an informed consent form. At the beginning of the session, all participants will be evaluated for their socio-demographic characteristics by a questionnaire created by the researchers, muscle viscoelastic properties by MyotonPRO, upper extremity muscle tone by Modified Ashworth Scale, upper extremity motor dexterity by Box and Block Test, and upper extremity joint range of motion by goniometer and by a phone application named as PhysioMaster. After the assessment, participants will be randomly assigned to two groups: open kinetic chain activity group and closed kinetic chain activity group. After performing the exercises, all evaluations will be conducted again. Thus, the aim is to understand the immediate effects of two different group exercises on the evaluated parameters.

Conditions

Stroke

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: TREATMENT
• Blinding Strategy: DOUBLE

Study Groups

Open Kinetic Chain Activity Group

Open kinetic chain activity will involve Flexion-Abduction-External Rotation and Flexion-Adduction-External Rotation patterns from the Proprioceptive Neuromuscular Facilitation (PNF). During the application, participants will lie on their back, and the pattern will be initiated from the opposite direction of the targeted movement. Participants will be encouraged to perform the movement as actively as possible. Assistance will be provided if the participant cannot complete the pattern. No other PNF techniques will be applied. Both patterns will be practiced for 10 repetitions. Resting periods will be provided as needed to prevent fatigue. The entire application is planned to last approximately 5 minutes.

Group Type: EXPERIMENTAL

Open Kinetic Chain Activity

Intervention Type: OTHER

PNF Flexion-Abduction-External Rotation and Flexion-Adduction-External Rotation patterns will be actively performed on the hemiplegic upper extremity.

Closed Kinetic Chain Activity Group

For closed kinetic chain activity of the upper extremity, an activity involving weight shifting onto the hands on a table while standing with the elbows in extension will be used. Participants will be asked to shift weight onto the hemiplegic upper extremity for 30 seconds. After a 30-second rest period, the weight shifting will be repeated for a second time.

Group Type: EXPERIMENTAL

Closed Kinetic Chain Activity

Intervention Type: OTHER

Weight-bearing on the hemiplegic hand with extended elbow in standing position

Interventions

Open Kinetic Chain Activity

PNF Flexion-Abduction-External Rotation and Flexion-Adduction-External Rotation patterns will be actively performed on the hemiplegic upper extremity.

Intervention Type: OTHER

Closed Kinetic Chain Activity

Weight-bearing on the hemiplegic hand with extended elbow in standing position

Intervention Type: OTHER

Eligibility Criteria

Inclusion Criteria

• Stroke diagnosis;
• Hemiplegia;
• Subacute&chronic phase (more than 3 months);
• Brunnstrom 3-4-5;
• Unsupported sitting ability;
• Being volunteer.

Exclusion Criteria

• Having Botox within the last 6 months;
• 4 according to Modified Ashworth Scale;
• Other neurological diagnosis other than stroke.

• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 70 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Istinye University

OTHER

Sponsor Role: lead

Responsible Party

Çiçek Günday

Principal Investigator

Responsibility Role: PRINCIPAL_INVESTIGATOR

Principal Investigators

Merve Can

Role: STUDY_CHAIR

Istinye University

Seyhan Söyüncü

Role: STUDY_CHAIR

Istinye University

Locations

Istinye University Hospital Medical Park Gaziosmanpasa

Istanbul, , Turkey (Türkiye)

Site Status: RECRUITING

Countries

Turkey (Türkiye)

Central Contacts

Çiçek GÜNDAY, PhD(c)

Role: CONTACT

cckdmn@gmail.com

+90 507 188 8848

Facility Contacts

Mehmet Salih Baran, Assist. Prof.

Role: primary

Other Identifiers

10102023

Identifier Type: -

Identifier Source: org_study_id