Evaluation of C-arm PCD-CBCT for Image-Guided Interventions

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

NOT_YET_RECRUITING

Total Enrollment

20 participants

Study Classification

OBSERVATIONAL

Study Start Date

2026-02-28

Study Completion Date

2027-11-30

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The overarching objective of the project is to develop a new C-arm interventional x-ray imaging platform that integrates both a photon counting detector and a flat panel detector to provide high image quality and quantitative spectral computed tomography (CT) image guidance will be developed to enable more accurate and safe interventional procedures for patients.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Benefit of Tin Filter in Regards to Image Quality and Radiation Dose in CT Scan Study of Pulmonary Parenchyma

NCT04119141

Tin X Ray Pulmonary Parenchyma

UNKNOWN NA

Clinical Evaluation of CARESTREAM Cone Beam Computed Tomography (CBCT)

NCT02445287

Healthy

COMPLETED NA

Photon Counting Detector CT Image Quality

NCT06281808

Diagnostic Imaging Tomography, X Ray Computed

ACTIVE_NOT_RECRUITING NA

Optimized Camera-based Patient Positioning in CT

NCT05135208

Radiation Dosage

COMPLETED

Use of Electrical Impedence to Measure Lean Body Weight as a Determinant of the Dose of Contrast Media for Abdominal CT

NCT02170688

IV Contrast Dosing

COMPLETED PHASE4

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

The objective of this pilot study is to assess the feasibility of acquiring high-quality images using new imaging concepts and methods. All imaging will be performed in addition to standard-of-care procedures and will not influence clinical decisions or patient management.

The endpoint of this project includes: 1) PCD-CBCT data will be processed to generate virtual non-iodine images for evaluating contrast extravasation, as well as virtual monoenergetic (VME) images. 2) Images will be analyzed retrospectively to evaluate image quality and explore potential clinical benefits of PCD-CBCT compared to flat panel detector cone beam CT (FPD-CBCT) and multidetector computed tomography (MDCT).

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Imaging

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Patients with SOC image-guided intervention

Patients undergoing a standard of care (SOC) image-guided intervention of the head or body

C-arm PCD-CBCT

Intervention Type DEVICE

A single research PCD-CBCT scan will be performed directly after the participant's SOC scan.

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

C-arm PCD-CBCT

A single research PCD-CBCT scan will be performed directly after the participant's SOC scan.

Intervention Type DEVICE

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Not pregnant or breastfeeding
* Scheduled to receive image-guided intervention (IGI) of the head or the body
* Pre-treatment multidetector computed tomography (MDCT) images available