Effects of Egoscue Exercises in Patients With Knee Osteoarthritis

NCT ID: NCT07063953

Last Updated: 2025-07-14

Basic Information

• Recruitment Status: NOT_YET_RECRUITING
• Clinical Phase: NA
• Total Enrollment: 42 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2025-07-31
• Study Completion Date: 2025-10-31

Brief Summary

Knee osteoarthritis (KOA) is a chronic, debilitating illness with multiple etiologies that affects the entire knee joint. It is a leading cause of disability among the elderly population and necessitates effective interventions beyond pharmacotherapy due to the associated risks.

This study will address the existing literature gap by focusing on a novel therapeutic approach known as 'Egoscue Exercises', for managing knee osteoarthritis in the affected population.

Detailed Description

This Randomized Controlled Trial will be conducted at Riphah Rehab Training and Research Center, Lahore and District Health Quarter Hospital (DHQ), Sahiwal in a time span of 8 months. A sample of 42 participants aged 45-65 years, diagnosed with Grade 02 and 03 Knee Osteoarthritis, will undergo a comprehensive physiotherapy protocol, which includes standard physiotherapy knee OA treatment, either alone or in combination with Egoscue exercises. Participants will receive a minimum of 3 sessions per week, across four weeks.

Randomization, conducted by computer-generated stratified randomization, will ensure unbiased allocation to the two groups. Data collection will be carried out at baseline, 2 weeks, and 4 weeks, and includes outcomes in the form of pain measured by Numeric Pain Rating Scale (NPRS), range of motion measured by Goniometer, and physical function evaluated by Western Ontario and McMaster Universities Arthritis (WOMAC) index. The single-blind study will incorporate rigorous statistical analysis, using IBM SPSS software, version 25 for descriptive statistics, normality, and intergroup differences via t-tests and U tests.

Conditions

Knee Osteoarthritis

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: TREATMENT
• Blinding Strategy: SINGLE

Study Groups

Egoscue Exercises

Warm Up Exercises (5 min) which includes Stretching ,Walking (Forward, Backward, Sideways), Arm Circles, Side bends, March on the spot, Knee lifts, Standing Gluteal Contractions , Sitting heel raises, Isolated hip flexor lifts on a towel, Supine groin stretch on towels, Static back, Sitting Knee Pillow Squeezes, Sitting floor, Progressive supine groin, Supine calf-hamstring stretch with a strap,Foot circles and point flexes, Cool Down and Breathing Exercises

Group Type: EXPERIMENTAL

Egoscue Exercises

Intervention Type: OTHER

Warm Up Exercises (5 min) which includes Stretching ,Walking (Forward, Backward, Sideways), Arm Circles, Side bends, March on the spot, Knee lifts, Standing Gluteal Contractions , Sitting heel raises, Isolated hip flexor lifts on a towel, Supine groin stretch on towels, Static back, Sitting Knee Pillow Squeezes, Sitting floor, Progressive supine groin, Supine calf-hamstring stretch with a strap,Foot circles and point flexes, Cool Down and Breathing Exercises

Standard Physical Therapy

Hot pack \& Transcutaneous Electric Nerve Stimulation (TENS) Myofascial Release Mulligan Mobilization with Movement Exercises

Group Type: ACTIVE_COMPARATOR

Standard Physical Therapy

Intervention Type: OTHER

Hot pack \& Transcutaneous Electric Nerve Stimulation (TENS) Myofascial Release Mulligan Mobilization with Movement Exercises

Interventions

Standard Physical Therapy

Hot pack \& Transcutaneous Electric Nerve Stimulation (TENS) Myofascial Release Mulligan Mobilization with Movement Exercises

Intervention Type: OTHER

Egoscue Exercises

Warm Up Exercises (5 min) which includes Stretching ,Walking (Forward, Backward, Sideways), Arm Circles, Side bends, March on the spot, Knee lifts, Standing Gluteal Contractions , Sitting heel raises, Isolated hip flexor lifts on a towel, Supine groin stretch on towels, Static back, Sitting Knee Pillow Squeezes, Sitting floor, Progressive supine groin, Supine calf-hamstring stretch with a strap,Foot circles and point flexes, Cool Down and Breathing Exercises

Intervention Type: OTHER

Eligibility Criteria

Inclusion Criteria

• Age group between 45 and 65 years ,
• Both genders male and female ,
• BMI ˃ 25 , and Knee OA clinically or radiologically diagnosed by Kellgren-Lawrence Method, Grade II and III

Exclusion Criteria

• Age less than 45 years or older than 65 years,
• BMI < 25, Knee OA in grade I and IV, and
• Patients on steroid therapy and intra articular injection

• Minimum Eligible Age: 45 Years
• Maximum Eligible Age: 65 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Riphah International University

OTHER

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Principal Investigators

Samrood Akram, PhD*

Role: PRINCIPAL_INVESTIGATOR

Riphah International University

Locations

Basharat Hospital, Sahiwal

Sahiwal, Punjab Province, Pakistan

Countries

Pakistan

Central Contacts

Samrood Akram, PhD Scholar

Role: CONTACT

samrood.akram@riphah.edu.pk.com

03324806143

Facility Contacts

Fouzia Basharat, MSPT

Role: primary

hananbasharat1@gmail.com

923368701931

References

Sharma L. Osteoarthritis of the Knee. N Engl J Med. 2021 Jan 7;384(1):51-59. doi: 10.1056/NEJMcp1903768. No abstract available.

Reference Type: BACKGROUND

PMID: 33406330 (View on PubMed)

Cui A, Li H, Wang D, Zhong J, Chen Y, Lu H. Global, regional prevalence, incidence and risk factors of knee osteoarthritis in population-based studies. EClinicalMedicine. 2020 Nov 26;29-30:100587. doi: 10.1016/j.eclinm.2020.100587. eCollection 2020 Dec.

Reference Type: BACKGROUND

PMID: 34505846 (View on PubMed)

Giorgino R, Albano D, Fusco S, Peretti GM, Mangiavini L, Messina C. Knee Osteoarthritis: Epidemiology, Pathogenesis, and Mesenchymal Stem Cells: What Else Is New? An Update. Int J Mol Sci. 2023 Mar 29;24(7):6405. doi: 10.3390/ijms24076405.

Reference Type: BACKGROUND

PMID: 37047377 (View on PubMed)

Kondal S, Kulkarni V, Gaikwad A, Kharat A, Pant A. Automatic Grading of Knee Osteoarthritis on the Kellgren-Lawrence Scale from Radiographs Using Convolutional Neural Networks [Internet]. arXiv.org. 2020 [cited 2024 Jun 25].

Reference Type: BACKGROUND

Yunus MHM, Nordin A, Kamal H. Pathophysiological Perspective of Osteoarthritis. Medicina (Kaunas). 2020 Nov 16;56(11):614. doi: 10.3390/medicina56110614.

Reference Type: BACKGROUND

PMID: 33207632 (View on PubMed)

Siddiq MAB, Clegg D, Jansen TL, Rasker JJ. Emerging and New Treatment Options for Knee Osteoarthritis. Curr Rheumatol Rev. 2022;18(1):20-32. doi: 10.2174/1573397117666211116111738.

Reference Type: BACKGROUND

PMID: 34784876 (View on PubMed)

Other Identifiers

REC/RCR &AHS/24/0146 Momina

Identifier Type: -

Identifier Source: org_study_id