Impact of Ultraviolet Radiation and Environmental Factors on Human Ocular Biomechanics
NCT ID: NCT06993077
Last Updated: 2025-05-28
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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ACTIVE_NOT_RECRUITING
3000 participants
OBSERVATIONAL
2025-01-01
2025-10-01
Brief Summary
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The main questions it aims to answer are:
Is there a significant correlation between UV radiation levels and corneal biomechanical parameters?
Do environmental factors such as geographic region and seasonal variation affect corneal biomechanical behavior?
Researchers will compare ocular biomechanical parameters among populations from different geographic regions with varying levels of UV radiation to determine whether there are statistically significant correlations or differences.
Participants will:
Undergo standardized ophthalmic examinations, including visual acuity, intraocular pressure, slit-lamp evaluation, axial length, and corneal topography;
Receive corneal biomechanical assessments using the Corvis ST device;
Provide basic demographic information and medical history;
Have all data de-identified, with the study strictly following ethical approval and privacy protection protocols.
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Detailed Description
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Conditions
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Study Design
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ECOLOGIC_OR_COMMUNITY
CROSS_SECTIONAL
Interventions
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environment Exposure
No special intervention
Eligibility Criteria
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Inclusion Criteria
Spherical equivalent refraction (SER) ≤ 6.00 diopters;
No other ocular diseases;
No systemic diseases (e.g., diabetes, hypertension, cardiovascular diseases);
No severe psychiatric or psychological disorders;
No history of ocular surgery.
Exclusion Criteria
Individuals diagnosed with keratoconus, suspected keratoconus, or subclinical keratoconus (based on the Global Consensus on Keratoconus Diagnosis);
Presence of other ocular diseases (e.g., glaucoma, corneal opacity, uveitis);
History of intraocular or ocular surface surgeries;
Presence of nystagmus or inability to cooperate with examinations;
History of intraocular surgery;
Presence of systemic diseases (e.g., diabetes, hypertension, cardiovascular diseases).
* Severe psychiatric disorders;
Individuals diagnosed with keratoconus, suspected keratoconus, or subclinical keratoconus (based on the Global Consensus on Keratoconus Diagnosis);
Presence of other ocular diseases (e.g., glaucoma, corneal opacity, uveitis);
History of intraocular or ocular surface surgeries;
Presence of nystagmus or inability to cooperate with examinations;
History of intraocular surgery;
Presence of systemic diseases (e.g., diabetes, hypertension, cardiovascular diseases).
18 Years
44 Years
ALL
Yes
Sponsors
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Tianjin Eye Hospital
OTHER
Responsible Party
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Locations
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Tianjin Eye Hospital
China, Tianjin Municipality, China
Countries
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Other Identifiers
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KY-2025010
Identifier Type: -
Identifier Source: org_study_id
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