Age and Refraction in Predicting Myopia Progression in COVID-19

NCT ID: NCT05305274

Last Updated: 2022-03-31

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

34400 participants

Study Classification

OBSERVATIONAL

Study Start Date

2019-10-01

Study Completion Date

2021-12-01

Brief Summary

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To determine the longitudinal changes of age and refraction in predicting myopia progression with risk under the coronavirus disease 2019 (COVID-19) pandemic in a 3-year follow-up of a Chinese cohort.

Detailed Description

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This was part of the large-scale Tianjin Eye Study, a population-based cohort study that longitudinally investigates the relationship between the age, refraction, and development of childhood RE in Tianjin, China.

Conditions

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Refraction Error Myopia

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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2019 screening

34,400 schoolchildren with a 36-month follow-up from 2019 to 2021.

screening

Intervention Type OTHER

This study included 34,400 students, as part of the Tianjin Eye Study who performed a 3-year follow-up from 2019 to 2021. All participants underwent yearly noncycloplegic refraction and ocular examinations. Time-related changes in sphere, cylinder, and spherical equivalent (SE) measurements in both sexes were analyzed.

2020 screening

34,400 schoolchildren with a 36-month follow-up from 2019 to 2021.

screening

Intervention Type OTHER

This study included 34,400 students, as part of the Tianjin Eye Study who performed a 3-year follow-up from 2019 to 2021. All participants underwent yearly noncycloplegic refraction and ocular examinations. Time-related changes in sphere, cylinder, and spherical equivalent (SE) measurements in both sexes were analyzed.

2021 screening

34,400 schoolchildren with a 36-month follow-up from 2019 to 2021.

screening

Intervention Type OTHER

This study included 34,400 students, as part of the Tianjin Eye Study who performed a 3-year follow-up from 2019 to 2021. All participants underwent yearly noncycloplegic refraction and ocular examinations. Time-related changes in sphere, cylinder, and spherical equivalent (SE) measurements in both sexes were analyzed.

Interventions

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screening

This study included 34,400 students, as part of the Tianjin Eye Study who performed a 3-year follow-up from 2019 to 2021. All participants underwent yearly noncycloplegic refraction and ocular examinations. Time-related changes in sphere, cylinder, and spherical equivalent (SE) measurements in both sexes were analyzed.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* no concurrent eye disease;
* age 6-15 years.

Exclusion Criteria

* significant systemic illnesses
* ocular conditions that could affect the corneal curvature, including congenital corneal diseases,
* pterygium, keratoconus, other corneal degeneration or dystrophy conditions,
* media opacity, uveitis, glaucoma
* a history of intraocular surgery, refractive surgery,
* neurologic or retinal diseases, current corneal refractive therapy (ortho-K),
* low-dose atropine therapy for myopia control
Minimum Eligible Age

6 Years

Maximum Eligible Age

15 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Tianjin Eye Hospital

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Yan Wang, director

Role: STUDY_CHAIR

Tianjin Eye Hospital

Locations

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Tianjin Eye Hospital

Tianjin, , China

Site Status

Countries

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China

References

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Hu Y, Zhao F, Ding X, Zhang S, Li Z, Guo Y, Feng Z, Tang X, Li Q, Guo L, Lu C, Yang X, He M. Rates of Myopia Development in Young Chinese Schoolchildren During the Outbreak of COVID-19. JAMA Ophthalmol. 2021 Oct 1;139(10):1115-1121. doi: 10.1001/jamaophthalmol.2021.3563.

Reference Type BACKGROUND
PMID: 34529002 (View on PubMed)

Ma D, Wei S, Li SM, Yang X, Cao K, Hu J, Fan S, Zhang L, Wang N. Progression of myopia in a natural cohort of Chinese children during COVID-19 pandemic. Graefes Arch Clin Exp Ophthalmol. 2021 Sep;259(9):2813-2820. doi: 10.1007/s00417-021-05305-x. Epub 2021 Jul 21.

Reference Type BACKGROUND
PMID: 34287693 (View on PubMed)

Other Identifiers

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2022018

Identifier Type: -

Identifier Source: org_study_id