Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
1000 participants
OBSERVATIONAL
2025-07-01
2028-12-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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COHORT
PROSPECTIVE
Study Groups
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Genetic and myopia onset
Identify genetic variants (GWAS/WES) associated with:
* Myopia onset risk (high-risk SNPs ).
* Myopia progression rate (e.g., axial elongation/year).
Oral swab DNA analyzed for myopia-related gene variants
Beyond detecting links between gene variants and myopia development, the testing analyzes how these variants influence treatment effectiveness. The aim is to enable early risk prediction and personalized treatment guidance for children through oral DNA testing.
Genetic and myopia intervention
Evaluate gene-intervention interactions for:
* Low-dose atropine (0.01%, 0.05%).
* Orthokeratology.
* Defocus-incorporated spectacles.
* Outdoor/sunlight exposure (≥2 hours/day).
Oral swab DNA analyzed for myopia-related gene variants
Beyond detecting links between gene variants and myopia development, the testing analyzes how these variants influence treatment effectiveness. The aim is to enable early risk prediction and personalized treatment guidance for children through oral DNA testing.
Interventions
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Oral swab DNA analyzed for myopia-related gene variants
Beyond detecting links between gene variants and myopia development, the testing analyzes how these variants influence treatment effectiveness. The aim is to enable early risk prediction and personalized treatment guidance for children through oral DNA testing.
Eligibility Criteria
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Inclusion Criteria
* Any Spherical equivalent refraction (SER)
* Parental consent for genetic testing.
Exclusion Criteria
* Other eye diseases (e.g., glaucoma, cataracts, retinal abnormalities, strabismus).
* Prior refractive surgery
6 Years
18 Years
ALL
Yes
Sponsors
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Beijing New Vision Eye Hospital
UNKNOWN
High Myopia Control Alliance (HIMALAYA)
UNKNOWN
Beijing Visionly Plus Eye Hospital
OTHER
Responsible Party
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Locations
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Beijing New Vision Eye Hospital
Beijing, , China
Beijing Visionly Plus Eye Hospital
Beijing, , China
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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Precvision202501
Identifier Type: -
Identifier Source: org_study_id
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