Analyzing the Changes in Eye Axis Length and Corneal Curvature in Central China

NCT ID: NCT06126302

Last Updated: 2023-11-13

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Total Enrollment

60000 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-11-05

Study Completion Date

2023-11-20

Brief Summary

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The Chinese lifestyle has undergone dramatic changes over the past century. In recent years, limited studies reported the changing trend in crucial eye parameters of people born in different decades. This multicenter study analyzed the axial length and average corneal curvature data from patients of four hospital. The trends in the axial length and corneal curvature will be observed.

Detailed Description

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The Chinese lifestyle has undergone dramatic changes over the past century. In recent years, limited studies reported the changing trend in crucial eye parameters of people born in different decades. This multicenter study analyzed the axial length and average corneal curvature data between 2012 and 2023. There were four clinical centers involved in this study. The study was approved by the Medical Ethics Committee of Zhongnan Hospital, Wuhan University, Yichang center hospital, Jingzhou center hospital , Yichang center hospital and Xiaogan center hospital, and conformed to the tenets of the Declaration of Helsinki. We divided the participants into ten groups of 10 years each based on their year of birth (called birth decade) and observed the trends in the axial length and corneal curvature in different groups.

Conditions

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Birth Year-dependent Eye Parameters Change

Study Design

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Observational Model Type

OTHER

Study Time Perspective

RETROSPECTIVE

Study Groups

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Before 1930

the patients were divided into ten groups according to the decade of their birth: before 1930

Birth year

Intervention Type OTHER

we divided the patients according to patients' birth year

1930-1939

the patients were divided into ten groups according to the decade of their birth: 1930-1939

Birth year

Intervention Type OTHER

we divided the patients according to patients' birth year

1940-1949

the patients were divided into ten groups according to the decade of their birth: 1940-1949

Birth year

Intervention Type OTHER

we divided the patients according to patients' birth year

1950-1959

the patients were divided into ten groups according to the decade of their birth: 1950-1959

Birth year

Intervention Type OTHER

we divided the patients according to patients' birth year

1960-1969

the patients were divided into ten groups according to the decade of their birth: 1960-1969

Birth year

Intervention Type OTHER

we divided the patients according to patients' birth year

1970-1979

the patients were divided into ten groups according to the decade of their birth: 1970-1979

Birth year

Intervention Type OTHER

we divided the patients according to patients' birth year

1980-1989

the patients were divided into ten groups according to the decade of their birth: 1980-1989

Birth year

Intervention Type OTHER

we divided the patients according to patients' birth year

1990-1999

the patients were divided into ten groups according to the decade of their birth: 1990-1999

Birth year

Intervention Type OTHER

we divided the patients according to patients' birth year

2000-2009

the patients were divided into ten groups according to the decade of their birth: 2000-2009

Birth year

Intervention Type OTHER

we divided the patients according to patients' birth year

after 2009

the patients were divided into ten groups according to the decade of their birth: after 2009

Birth year

Intervention Type OTHER

we divided the patients according to patients' birth year

Interventions

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Birth year

we divided the patients according to patients' birth year

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

\- Eligible patients were those aged ≥7 years and who underwent intraocular lens (IOL) Master (version 5.5) biometry for routine examination of cataract or refractive examination (ametropia and presbyopia) between April 2012 and November October 2023. Only patients who would cooperate with examinations to ensure stable and repeatable data (AL was measured 5 times or more, CC was measured 3 times or more, and the coefficient of variation of the measured results were≤15%a coefficient of variation ≤15% was considered low variation) were selected.
Minimum Eligible Age

7 Years

Maximum Eligible Age

130 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Min Ke

OTHER

Sponsor Role lead

Responsible Party

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Min Ke

Department of ophthalmology, Zhongnan Hospital

Responsibility Role SPONSOR_INVESTIGATOR

Other Identifiers

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20231105

Identifier Type: -

Identifier Source: org_study_id

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