Clinical Evaluation of Two Different Surgical Techniques With PRF in the Treatment of Multiple Gingival Recessions

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Clinical Phase

NA

Total Enrollment

10 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-08-15

Study Completion Date

2026-03-15

Brief Summary

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This prospective clinical study aims to evaluate and compare the effectiveness of coronally advanced flap (CAF) and tunnel techniques, both combined with platelet-rich fibrin (PRF), in the treatment of multiple Miller Class I-II gingival recessions. Eleven participants with bilateral defects will be treated using a split-mouth design. Periodontal parameters will be assessed at baseline, 3 months, and 6 months.

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Detailed Description

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The objective of this prospective clinical trial is to compare two mucogingival surgical techniques-coronally advanced flap (CAF) and tunnel technique-used in combination with platelet-rich fibrin (PRF) for treating multiple Miller Class I-II gingival recessions. Eleven systemically healthy participants with bilateral gingival recessions will be enrolled. CAF+PRF will be applied on one side, and Tunnel+PRF on the contralateral side. Clinical parameters including plaque index, gingival index, bleeding on probing, probing depth, clinical attachment level, recession height and width, and keratinized tissue height will be recorded at baseline, 3 months, and 6 months. Root coverage outcomes and clinical attachment gain will be analyzed.

Conditions

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Gingival Recession

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Split-mouth randomized design. Each participant receives both interventions, one per side of the mouth.

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

The clinical examiner who recorded the outcome measures was blinded to the type of surgical technique applied on each side.

Study Groups

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CAF + PRF

This group will receive coronally advanced flap (CAF) surgery combined with platelet-rich fibrin (PRF) for the treatment of multiple gingival recessions.

Group Type EXPERIMENTAL

CAF with PRF

Intervention Type PROCEDURE

Coronally advanced flap technique will be performed to reposition the gingival margin coronally. Platelet-rich fibrin (PRF) membranes will be placed over the exposed root surfaces and stabilized with sutures.

Tunnel + PRF

This group will receive tunnel surgical technique combined with platelet-rich fibrin (PRF) for the treatment of multiple gingival recessions.

Group Type EXPERIMENTAL

Tunnel with PRF

Intervention Type PROCEDURE

A tunnel or subgingival pouch will be created using microsurgical instruments without vertical incisions. Platelet-rich fibrin (PRF) membranes will be inserted into the tunnel and the gingival tissue will be advanced coronally and sutured to cover the recession.

Interventions

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CAF with PRF

Coronally advanced flap technique will be performed to reposition the gingival margin coronally. Platelet-rich fibrin (PRF) membranes will be placed over the exposed root surfaces and stabilized with sutures.

Intervention Type PROCEDURE

Tunnel with PRF

A tunnel or subgingival pouch will be created using microsurgical instruments without vertical incisions. Platelet-rich fibrin (PRF) membranes will be inserted into the tunnel and the gingival tissue will be advanced coronally and sutured to cover the recession.

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Age 18 years or older
* Systemically healthy individuals
* Presence of bilateral Miller Class I-II multiple gingival recessions
* Good oral hygiene and willingness to follow instructions
* Signed informed consent

Exclusion Criteria

* Use of tobacco or smoking
* Pregnancy or lactation
* Presence of systemic diseases affecting periodontal health
* Use of medications that may affect healing (e.g., corticosteroids)
* Periodontal surgery in the same area within the last 6 months

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes