Clinical Evaluation of Injectable Platelet Rich Fibrin With Connective Tissue Graft for the Treatment of Deep Gingival Recession Defects.

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

72 participants

Study Classification

INTERVENTIONAL

Study Start Date

2017-11-01

Study Completion Date

2019-03-30

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

Aim: The aim of this study was to determine whether the combined connective tissue graft (CTG) with injectable platelet rich fibrin (i-prf) with coronally advanced flap (CAF) improved root coverage of deep Miller Class I or II gingival recessions compared to CTG alone with CAF.

Methods: Seventy-two patients with Miller class I and II gingival recessions were enrolled. Thirty-six patients were randomly assigned to the test group (CAF+CTG+i-prf) or control group (CAF+CTG). Clinical evaluations were made at 6 months

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Platelet-rich Fibrin and Connective Tissue Graft in Recession Treatment

NCT02397122

Gingival Recession

COMPLETED NA

Effect of Connective Tissue Graft Position

NCT04181892

Gingival Recession

COMPLETED NA

Effect of Dose-dependent Platelet Rich Fibrin(PRF)

NCT02882464

Gingival Recession

COMPLETED NA

Platelet Rich Fibrin in the Treatment of Multiple Gingival Recessions

NCT02018120

Gingival Recession

COMPLETED NA

Platelet-Rich Fibrin in the Treatment of Multiple Gingival Recessions

NCT02335866

Gingival Recessions

COMPLETED EARLY_PHASE1

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Gingival Recession

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

TRIPLE

Participants Investigators Outcome Assessors

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

CAF+CTG

the combined connective tissue graft (CTG) with coronally advanced flap (CAF)

Group Type ACTIVE_COMPARATOR

CAF+CTG+i-prf

Intervention Type PROCEDURE

combined connective tissue graft (CTG) and injectable platelet rich fibrin (i-prf) with coronally advanced flap (CAF)

CAF+CTG+i-prf

the combined connective tissue graft (CTG) and injectable platelet rich fibrin (i-prf) with coronally advanced flap (CAF)

Group Type EXPERIMENTAL

CAF+CTG+i-prf

Intervention Type PROCEDURE

combined connective tissue graft (CTG) and injectable platelet rich fibrin (i-prf) with coronally advanced flap (CAF)

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

CAF+CTG+i-prf

combined connective tissue graft (CTG) and injectable platelet rich fibrin (i-prf) with coronally advanced flap (CAF)

Intervention Type PROCEDURE

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* ≥19 years of age,
* Periodontally and systemically healthy,
* FMPS and FMBS \<15%,
* Presence of deep Miller class I and II gingival recession defect (≥3 mm in depth) at the buccal aspect of incisors,