The Comparison of the Efficacy of Gingival Unit Graft With Connective Tissue Graft in Root Coverage

NCT ID: NCT04637451

Last Updated: 2020-11-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

16 participants

Study Classification

INTERVENTIONAL

Study Start Date

2015-07-01

Study Completion Date

2016-07-30

Brief Summary

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The purpose of the study is to compare the clinical effectiveness of gingival unit graft (GUG) and connective tissues graft (CTG) in Miller's class I and II gingival recession.

Detailed Description

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Patients who accept the study have provided information about the study and required a written informed consent form. The clinical effectiveness of two different periodontal surgical techniques (gingival unit graft and connective tissue graft) in gingival recessions will be evaluated. Periodontal measurements (gingival recession, keratinized gingiva height) and patient-reported outcomes (intra and post-operative pain, patient satisfaction and hypersensitivity) are defined.

Conditions

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Gingival Recession Periodontal Diseases

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Gingival Unit Graft

For test group, gingival recessions were treated with gingival unit graft.

Group Type EXPERIMENTAL

Root coverage treatment

Intervention Type PROCEDURE

Gingival unit graft Connective tissue graft

Connective Tissue Graft

For Control group, gingival recessions were treated with connective tissue graft.

Group Type OTHER

Root coverage treatment

Intervention Type PROCEDURE

Gingival unit graft Connective tissue graft

Interventions

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Root coverage treatment

Gingival unit graft Connective tissue graft

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Systemic healthy individuals
* Presence Miller's class I and II gingival recession in the anterior and premolar teeth

Exclusion Criteria

* Age \<18 years
* Pregnancy
* Lactation
* Any cardiovascular, renal or hepatic conditions
* History of periodontal surgery
* Tooth mobility
* Presence of probing depth \>3 mm and caries or restorations in the teeth undergoing treatment
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Okan University

OTHER

Sponsor Role lead

Responsible Party

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Sibel Kayaalti-Yuksek

Assistant Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Sibel Kayaaltı Yüksek

Istanbul, Tuzla, Turkey (Türkiye)

Site Status

Countries

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Turkey (Türkiye)

References

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Zucchelli G, Mounssif I. Periodontal plastic surgery. Periodontol 2000. 2015 Jun;68(1):333-68. doi: 10.1111/prd.12059.

Reference Type BACKGROUND
PMID: 25867992 (View on PubMed)

Cairo F, Pagliaro U, Buti J, Baccini M, Graziani F, Tonelli P, Pagavino G, Tonetti MS. Root coverage procedures improve patient aesthetics. A systematic review and Bayesian network meta-analysis. J Clin Periodontol. 2016 Nov;43(11):965-975. doi: 10.1111/jcpe.12603. Epub 2016 Sep 16.

Reference Type BACKGROUND
PMID: 27454460 (View on PubMed)

Allen AL. Use of the gingival unit transfer in soft tissue grafting: report of three cases. Int J Periodontics Restorative Dent. 2004 Apr;24(2):165-75.

Reference Type BACKGROUND
PMID: 15119887 (View on PubMed)

Kuru B, Yildirim S. Treatment of localized gingival recessions using gingival unit grafts: a randomized controlled clinical trial. J Periodontol. 2013 Jan;84(1):41-50. doi: 10.1902/jop.2012.110685. Epub 2012 Mar 5.

Reference Type BACKGROUND
PMID: 22390550 (View on PubMed)

Yildirim S, Kuru B. Gingival unit transfer using in the Miller III recession defect treatment. World J Clin Cases. 2015 Feb 16;3(2):199-203. doi: 10.12998/wjcc.v3.i2.199.

Reference Type BACKGROUND
PMID: 25685769 (View on PubMed)

Del Pizzo M, Modica F, Bethaz N, Priotto P, Romagnoli R. The connective tissue graft: a comparative clinical evaluation of wound healing at the palatal donor site. A preliminary study. J Clin Periodontol. 2002 Sep;29(9):848-54. doi: 10.1034/j.1600-051x.2002.290910.x.

Reference Type BACKGROUND
PMID: 12423299 (View on PubMed)

Douglas de Oliveira DW, Oliveira-Ferreira F, Flecha OD, Goncalves PF. Is surgical root coverage effective for the treatment of cervical dentin hypersensitivity? A systematic review. J Periodontol. 2013 Mar;84(3):295-306. doi: 10.1902/jop.2012.120143. Epub 2012 May 1.

Reference Type BACKGROUND
PMID: 22548583 (View on PubMed)

Camargo PM, Melnick PR, Kenney EB. The use of free gingival grafts for aesthetic purposes. Periodontol 2000. 2001;27:72-96. doi: 10.1034/j.1600-0757.2001.027001072.x. No abstract available.

Reference Type BACKGROUND
PMID: 11551301 (View on PubMed)

Kayaalti-Yuksek S, Yaprak E. The comparison of the efficacy of gingival unit graft with connective tissue graft in recession defect coverage: a randomized split-mouth clinical trial. Clin Oral Investig. 2022 Mar;26(3):2761-2770. doi: 10.1007/s00784-021-04252-5. Epub 2021 Nov 17.

Reference Type DERIVED
PMID: 34787718 (View on PubMed)

Other Identifiers

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2015/174

Identifier Type: -

Identifier Source: org_study_id